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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)

Phase 3
Terminated
Conditions
Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions
Drug: Standard of Care Chemotherapy
Drug: Blinatumomab
First Posted Date
2013-12-17
Last Posted Date
2024-03-05
Lead Sponsor
Amgen
Target Recruit Count
405
Registration Number
NCT02013167
Locations
🇬🇧

Research Site, Sutton, United Kingdom

Retrospective Analysis of Survival in Adult MRD Positive Acute Lymphoblastic Leukemia Patients

Completed
Conditions
Acute Lymphoblastic Leukemia
First Posted Date
2013-12-13
Last Posted Date
2022-09-15
Lead Sponsor
Amgen
Target Recruit Count
310
Registration Number
NCT02010931
Locations
🇬🇧

Research Site, London, United Kingdom

Historical Data Analysis of Hematological Remission and Survival in Adults With R/R Acute Lymphoblastic Leukemia

Completed
Conditions
Acute Lymphoblastic Leukemia
Interventions
Other: Not applicable - observational study
First Posted Date
2013-12-06
Last Posted Date
2022-11-07
Lead Sponsor
Amgen
Target Recruit Count
2373
Registration Number
NCT02003612
Locations
🇬🇧

Research Site, London, United Kingdom

Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia

Phase 2
Completed
Conditions
Relapsed/Refractory Philadelphia Positive B-precursor ALL
Interventions
First Posted Date
2013-12-04
Last Posted Date
2024-05-28
Lead Sponsor
Amgen
Target Recruit Count
45
Registration Number
NCT02000427
Locations
🇬🇧

Research Site, Sutton, United Kingdom

Efficacy, Safety and Tolerability of Romosozumab in the Treatment of Japanese Women With Postmenopausal Osteoporosis

Phase 2
Completed
Conditions
Postmenopausal Osteoporosis (PMO)
Interventions
Drug: Placebo
Drug: Romosozumab
First Posted Date
2013-11-25
Last Posted Date
2019-03-25
Lead Sponsor
Amgen
Target Recruit Count
252
Registration Number
NCT01992159
Locations
🇯🇵

Research Site, Toshima-ku, Tokyo, Japan

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3

Phase 3
Completed
Conditions
Hyperlipidemia
Interventions
Drug: Ezetimibe
Other: Placebo to Ezetimibe
Drug: Evolocumab
Drug: Atorvastatin
Drug: Placebo to Atorvastatin
Other: Placebo to Evolocumab
First Posted Date
2013-11-14
Last Posted Date
2018-11-29
Lead Sponsor
Amgen
Target Recruit Count
511
Registration Number
NCT01984424
Locations
🇬🇧

Research Site, Newcastle upon Tyne, United Kingdom

Osteonecrosis of the Jaw (ONJ) and Infection Among Nordic Cancer Patients Treated With XGEVA™ or Zoledronic Acid

Completed
Conditions
Osteonecrosis of the Jaw
Infection Leading to Hospitalization
First Posted Date
2013-10-22
Last Posted Date
2023-06-22
Lead Sponsor
Amgen
Target Recruit Count
2560
Registration Number
NCT01967160

Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide

Phase 3
Completed
Conditions
Hyperparathyroidism, Secondary
Interventions
First Posted Date
2013-08-30
Last Posted Date
2018-10-17
Lead Sponsor
Amgen
Target Recruit Count
158
Registration Number
NCT01932970
Locations
🇺🇸

Research Site, Hampton, Virginia, United States

Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab

Phase 4
Terminated
Conditions
Moderate to Severe Rheumatoid Arthritis
Interventions
Biological: Etanercept
Drug: Methotrexate
First Posted Date
2013-08-23
Last Posted Date
2018-01-30
Lead Sponsor
Amgen
Target Recruit Count
90
Registration Number
NCT01927757
Locations
🇵🇷

Research Site, Caguas, Puerto Rico

A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: AMG 282
Drug: AMG 282 Matching Placebo
First Posted Date
2013-08-23
Last Posted Date
2016-12-14
Lead Sponsor
Amgen
Target Recruit Count
70
Registration Number
NCT01928368
Locations
🇺🇸

Research Site, Seattle, Washington, United States

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