Amgen, Inc.

- Country
- 🇺🇸United States
- Ownership
- Public
- Established
- 1980-01-01
- Employees
- 26.7K
- Market Cap
- $175.6B
- Website
- http://www.amgen.com
Clinical Trials
1.1k
Trial Phases
6 Phases
Drug Approvals
3
Clinical Trials
Distribution across different clinical trial phases (1008 trials with phase data)• Click on a phase to view related trials
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Conditions
- Heart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection FractionObesity
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-06-25
- Last Posted Date
- 2025-06-25
- Lead Sponsor
- Amgen
- Target Recruit Count
- 5056
- Registration Number
- NCT07037459
A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)
- Conditions
- Extensive Stage Small Cell Lung Cancer
- Interventions
- First Posted Date
- 2025-06-25
- Last Posted Date
- 2025-06-25
- Lead Sponsor
- Amgen
- Target Recruit Count
- 380
- Registration Number
- NCT07037758
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
- Conditions
- Atherosclerotic Cardiovascular DiseaseOverweightObesity
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-06-25
- Last Posted Date
- 2025-06-25
- Lead Sponsor
- Amgen
- Target Recruit Count
- 12800
- Registration Number
- NCT07037433
A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)
- Conditions
- Small-cell Lung CancerExtensive Stage Small-cell Lung Cancer
- Interventions
- First Posted Date
- 2025-06-05
- Last Posted Date
- 2025-06-05
- Lead Sponsor
- Amgen
- Target Recruit Count
- 330
- Registration Number
- NCT07005128
Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease
- First Posted Date
- 2025-05-23
- Last Posted Date
- 2025-06-27
- Lead Sponsor
- Amgen
- Target Recruit Count
- 272
- Registration Number
- NCT06987695
- Locations
- 🇯🇵
MIH Clinic Yoyogi, Shibuya-ku, Tokyo, Japan
🇯🇵Shinjuku Southern Clinic, Shinjuku-ku, Tokyo, Japan
🇯🇵Ikebukuro Metropolitan Clinic, Toshima-ku, Tokyo, Japan
- Prev
- 1
- 2
- 3
- 4
- 5
- 180
- Next
News
Crescent Biopharma Appoints Jan Pinkas as Chief Scientific Officer to Advance Oncology Pipeline
Crescent Biopharma has appointed Jan Pinkas, Ph.D., as chief scientific officer, bringing over two decades of oncology drug development experience including expertise in antibody-drug conjugates.
Oxford BioTherapeutics and Boehringer Ingelheim Advance Third Oncology Drug Candidate to IND-Enabling Studies
Oxford BioTherapeutics announced that Boehringer Ingelheim has selected a third drug candidate targeting OB33 to advance into IND-enabling studies under their ongoing collaboration.
EPO and UPC Reach Opposite Conclusions on Amgen's PCSK9 Antibody Patent Validity
The European Patent Office (EPO) Opposition Division upheld Amgen's PCSK9 antibody patent EP 3666797, finding it inventive, while the Unified Patent Court (UPC) Central Division revoked the same patent for lacking inventive step.
bluebird bio Strengthens Leadership Team with Three Key Executive Appointments
bluebird bio, a pioneer in gene therapies for severe genetic diseases, has appointed three new executives to strengthen its leadership team as the company focuses on commercial execution.
Sandoz Invests $1.1 Billion in European Biosimilar Manufacturing Hub to Capture $222 Billion Market Opportunity
Sandoz has broken ground on a $440 million biosimilar manufacturing facility in Brnik, Slovenia, bringing total planned investment in the country to over $1.1 billion by 2029.
Avacta Strengthens Leadership Team with Appointment of Chief Medical Officer and Business Development Advisor
Avacta Group plc has appointed David Liebowitz, M.D., Ph.D. as Chief Medical Officer to lead clinical strategy and execution for its targeted cancer therapy pipeline.
Amgen's Bemarituzumab Shows Significant Survival Benefit in Phase 3 Gastric Cancer Trial
Amgen's Phase 3 FORTITUDE-101 trial met its primary endpoint, demonstrating that bemarituzumab plus chemotherapy significantly improved overall survival compared to chemotherapy alone in patients with FGFR2b-positive gastric cancer.
Amgen Escalates Patent Defense with Three New Biosimilar Lawsuits Targeting Denosumab Competitors
Amgen filed three separate BPCIA patent infringement lawsuits in late June 2025 against companies developing denosumab biosimilars, including Hikma/Gedeon Richter, Shanghai Henlius/Organon, and Biocon.
KIF18A Emerges as Promising Cancer Target with Multiple Therapies Advancing Through Clinical Trials
KIF18A, a mitotic motor protein overexpressed in chromosomally unstable tumors, has emerged as a compelling therapeutic target for cancer treatment due to its selective expression in cancer cells versus normal tissue.
Galapagos Appoints Former Horizon CFO Aaron Cox to Lead Strategic Transformation
Galapagos NV has appointed Aaron Cox as Chief Financial Officer effective July 7, 2025, bringing over two decades of biotechnology and M&A expertise to the Belgian biotech company.