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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

A Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity

Phase 1
Completed
Conditions
Obesity
Overweight
Interventions
First Posted Date
2025-05-16
Last Posted Date
2025-05-16
Lead Sponsor
Amgen
Target Recruit Count
120
Registration Number
NCT06976372
Locations
🇺🇸

CenExel, Anaheim, California, United States

🇺🇸

CenExel Collaborative Neuroscience Research, LLC Los Alamitos, Los Alamitos, California, United States

🇺🇸

Fortrea Clinical Research Unit - Dallas, Dallas, Texas, United States

Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
Drug: AMG 378
Drug: Placebo
First Posted Date
2025-04-04
Last Posted Date
2025-04-17
Lead Sponsor
Amgen
Target Recruit Count
92
Registration Number
NCT06910709
Locations
🇺🇸

Orange County Research Center, Lake Forest, California, United States

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC)

Phase 1
Recruiting
Conditions
Small Cell Lung Cancer
Interventions
First Posted Date
2025-03-27
Last Posted Date
2025-05-14
Lead Sponsor
Amgen
Target Recruit Count
200
Registration Number
NCT06898957
Locations
🇺🇸

Washington University, Saint Louis, Missouri, United States

🇨🇳

Shandong Cancer Hospital, Jinan, Shandong, China

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Phase 3
Recruiting
Conditions
Obesity
Interventions
First Posted Date
2025-03-05
Last Posted Date
2025-05-14
Lead Sponsor
Amgen
Target Recruit Count
3501
Registration Number
NCT06858839
Locations
🇺🇸

Indago Research and Health Center, Hialeah, Florida, United States

🇺🇸

Yale School of Medicine, New Haven, Connecticut, United States

🇺🇸

Pinnacle Research Group LLC, Anniston, Alabama, United States

and more 99 locations

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Phase 3
Recruiting
Conditions
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Interventions
First Posted Date
2025-03-05
Last Posted Date
2025-05-14
Lead Sponsor
Amgen
Target Recruit Count
999
Registration Number
NCT06858878
Locations
🇺🇸

Alliance for Multispecialty Research Mobile, Mobile, Alabama, United States

🇺🇸

Gilbert Center for Family Medicine, Gilbert, Arizona, United States

🇺🇸

Desert Clinical Research, Mesa, Arizona, United States

and more 69 locations

A Study to Determine the Feasibility of Online Recruitment of People Using an Anti-Obesity Medication for Weight Loss

Completed
Conditions
Obesity
First Posted Date
2025-01-07
Last Posted Date
2025-01-14
Lead Sponsor
Amgen
Target Recruit Count
200
Registration Number
NCT06761703
Locations
🇺🇸

YourBio Health/CRT, Medford, Massachusetts, United States

A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)

Phase 3
Recruiting
Conditions
Sjögren's Syndrome
Interventions
First Posted Date
2024-12-24
Last Posted Date
2025-05-15
Lead Sponsor
Amgen
Target Recruit Count
844
Registration Number
NCT06747949
Locations
🇺🇸

Bradenton Research Center Inc, Bradenton, Florida, United States

🇺🇸

Arthritis, Rheumatic & Bone Disease Associates - P, Voorhees, New Jersey, United States

🇺🇸

Arizona Arthritis and Rheumatology Associates - Gilbert - 3645 S Rome St, Gilbert, Arizona, United States

and more 2 locations

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC

Phase 2
Recruiting
Conditions
Small Cell Lung Cancer (SCLC)
Interventions
First Posted Date
2024-12-20
Last Posted Date
2025-05-15
Lead Sponsor
Amgen
Target Recruit Count
240
Registration Number
NCT06745323
Locations
🇹🇷

Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi, Ankara, Turkey

🇺🇸

New York Oncology Hematology PC, Albany, New York, United States

🇺🇸

FirstHealth Cancer Center, Pinehurst, North Carolina, United States

and more 19 locations

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

Phase 3
Recruiting
Conditions
Relapsing-remitting Multiple Sclerosis (RRMS)
Interventions
First Posted Date
2024-11-22
Last Posted Date
2025-05-15
Lead Sponsor
Amgen
Target Recruit Count
444
Registration Number
NCT06700343
Locations
🇺🇸

Profound Research - Neurology Center of Southern California, Carlsbad, California, United States

🇺🇸

Mountain Neurological Research Center, Basalt, Colorado, United States

🇺🇸

Advanced Neurosciences Research, Llc, Fort Collins, Colorado, United States

and more 18 locations

Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer

Phase 3
Recruiting
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
First Posted Date
2024-11-18
Last Posted Date
2025-05-15
Lead Sponsor
Amgen
Target Recruit Count
675
Registration Number
NCT06691984
Locations
🇨🇦

Sir Mortimer B Davis - Jewish General Hospital, Montreal, Quebec, Canada

🇩🇰

Vejle Sygehus, Vejle, Denmark

🇺🇸

City of Hope National Medical Center, Duarte, California, United States

and more 52 locations
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