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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Clinical Trials

1.1k

Active:166
Completed:758

Trial Phases

6 Phases

Early Phase 1:2
Phase 1:365
Phase 2:256
+3 more phases

Drug Approvals

3

FDA:3

Drug Approvals

XGEVA

Approval Date
Jan 12, 2024
FDA

TEZSPIRE

Approval Date
May 26, 2023
FDA

NEUPOGEN

Approval Date
Apr 18, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (1008 trials with phase data)• Click on a phase to view related trials

Phase 1
365 (36.2%)
Phase 3
299 (29.7%)
Phase 2
256 (25.4%)
Phase 4
78 (7.7%)
Not Applicable
7 (0.7%)
Early Phase 1
2 (0.2%)
phase_1_2
1 (0.1%)

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Phase 3
Not yet recruiting
Conditions
Heart Failure With Preserved Ejection Fraction
Heart Failure With Mildly Reduced Ejection Fraction
Obesity
Interventions
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
Amgen
Target Recruit Count
5056
Registration Number
NCT07037459

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Phase 1
Not yet recruiting
Conditions
Extensive Stage Small Cell Lung Cancer
Interventions
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
Amgen
Target Recruit Count
380
Registration Number
NCT07037758

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Phase 3
Not yet recruiting
Conditions
Atherosclerotic Cardiovascular Disease
Overweight
Obesity
Interventions
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
Amgen
Target Recruit Count
12800
Registration Number
NCT07037433

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Phase 3
Not yet recruiting
Conditions
Small-cell Lung Cancer
Extensive Stage Small-cell Lung Cancer
Interventions
First Posted Date
2025-06-05
Last Posted Date
2025-06-05
Lead Sponsor
Amgen
Target Recruit Count
330
Registration Number
NCT07005128

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease

Phase 3
Recruiting
Conditions
Obesity Disease
Interventions
First Posted Date
2025-05-23
Last Posted Date
2025-06-27
Lead Sponsor
Amgen
Target Recruit Count
272
Registration Number
NCT06987695
Locations
🇯🇵

MIH Clinic Yoyogi, Shibuya-ku, Tokyo, Japan

🇯🇵

Shinjuku Southern Clinic, Shinjuku-ku, Tokyo, Japan

🇯🇵

Ikebukuro Metropolitan Clinic, Toshima-ku, Tokyo, Japan

and more 24 locations
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News

Crescent Biopharma Appoints Jan Pinkas as Chief Scientific Officer to Advance Oncology Pipeline

Crescent Biopharma has appointed Jan Pinkas, Ph.D., as chief scientific officer, bringing over two decades of oncology drug development experience including expertise in antibody-drug conjugates.

Oxford BioTherapeutics and Boehringer Ingelheim Advance Third Oncology Drug Candidate to IND-Enabling Studies

Oxford BioTherapeutics announced that Boehringer Ingelheim has selected a third drug candidate targeting OB33 to advance into IND-enabling studies under their ongoing collaboration.

EPO and UPC Reach Opposite Conclusions on Amgen's PCSK9 Antibody Patent Validity

The European Patent Office (EPO) Opposition Division upheld Amgen's PCSK9 antibody patent EP 3666797, finding it inventive, while the Unified Patent Court (UPC) Central Division revoked the same patent for lacking inventive step.

bluebird bio Strengthens Leadership Team with Three Key Executive Appointments

bluebird bio, a pioneer in gene therapies for severe genetic diseases, has appointed three new executives to strengthen its leadership team as the company focuses on commercial execution.

Sandoz Invests $1.1 Billion in European Biosimilar Manufacturing Hub to Capture $222 Billion Market Opportunity

Sandoz has broken ground on a $440 million biosimilar manufacturing facility in Brnik, Slovenia, bringing total planned investment in the country to over $1.1 billion by 2029.

Avacta Strengthens Leadership Team with Appointment of Chief Medical Officer and Business Development Advisor

Avacta Group plc has appointed David Liebowitz, M.D., Ph.D. as Chief Medical Officer to lead clinical strategy and execution for its targeted cancer therapy pipeline.

Amgen's Bemarituzumab Shows Significant Survival Benefit in Phase 3 Gastric Cancer Trial

Amgen's Phase 3 FORTITUDE-101 trial met its primary endpoint, demonstrating that bemarituzumab plus chemotherapy significantly improved overall survival compared to chemotherapy alone in patients with FGFR2b-positive gastric cancer.

Amgen Escalates Patent Defense with Three New Biosimilar Lawsuits Targeting Denosumab Competitors

Amgen filed three separate BPCIA patent infringement lawsuits in late June 2025 against companies developing denosumab biosimilars, including Hikma/Gedeon Richter, Shanghai Henlius/Organon, and Biocon.

KIF18A Emerges as Promising Cancer Target with Multiple Therapies Advancing Through Clinical Trials

KIF18A, a mitotic motor protein overexpressed in chromosomally unstable tumors, has emerged as a compelling therapeutic target for cancer treatment due to its selective expression in cancer cells versus normal tissue.

Galapagos Appoints Former Horizon CFO Aaron Cox to Lead Strategic Transformation

Galapagos NV has appointed Aaron Cox as Chief Financial Officer effective July 7, 2025, bringing over two decades of biotechnology and M&A expertise to the Belgian biotech company.

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