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Amgen, Inc.

🇺🇸United States

Country: 🇺🇸United States

Ownership: Public

Established: 1980-01-01

Employees: 26.7K

Market Cap: $175.6B

Website: http://www.amgen.com

Clinical Trials

A Study to Evaluate Rocatinlimab (AMG 451) in Healthy Chinese Participants

Phase 1

Completed

Conditions: Atopic Dermatitis

Interventions: Drug: Rocatinlimab

First Posted Date: 2024-01-19

Last Posted Date: 2024-11-19

Lead Sponsor: Amgen

Target Recruit Count: 20

Registration Number: NCT06214481

Locations: 🇨🇳
Huashan Hospital Affiliated to Fudan University?, Shanghai, China

Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab

Phase 3

Recruiting

Conditions: Extensive-Stage Small-Cell Lung Cancer
Small-Cell Lung Cancer

Interventions: Drug: Tarlatamab
Drug: Durvalumab

First Posted Date: 2024-01-18

Last Posted Date: 2025-07-04

Lead Sponsor: Amgen

Target Recruit Count: 550

Registration Number: NCT06211036

Locations: 🇺🇸
Infirmary Cancer Center, Mobile, Alabama, United States
🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸
Yale New Haven Hospital, New Haven, Connecticut, United States

and more 215 locations

Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin

Phase 1

Completed

Conditions: Healthy Volunteers

Interventions: Drug: Avacopan
Drug: Simvastatin

First Posted Date: 2024-01-17

Last Posted Date: 2024-01-17

Lead Sponsor: Amgen

Target Recruit Count: 32

Registration Number: NCT06207682

Locations: 🇺🇸
Celerion, Tempe, Arizona, United States

Long-term, Open-label, Safety Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorder (NMOSD)

Phase 4

Recruiting

Conditions: Neuromyelitis Optica Spectrum Disorder

Interventions: Other: Blood tests
Drug: Inebilizumab

First Posted Date: 2023-12-22

Last Posted Date: 2025-05-22

Lead Sponsor: Amgen

Target Recruit Count: 30

Registration Number: NCT06180278

Locations: 🇹🇭
Khon Kaen University, Srinagarind Hospital - Division of Neurology, Depart, Khon Kaen, Thailand
🇺🇸
Wayne State University School of Medicine, Detroit, Michigan, United States
🇺🇸
Baylor College of Medicine, Houston, Texas, United States

and more 8 locations

Aimovig Pregnancy Exposure Registry

Recruiting

Conditions: Migraine

Interventions: Drug: erenumab-aooe

First Posted Date: 2023-11-29

Last Posted Date: 2024-10-03

Lead Sponsor: Amgen

Target Recruit Count: 2842

Registration Number: NCT06150781

Locations: 🇺🇸
IQVIA Virtual Site, Durham, North Carolina, United States

A Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With Moderate to Severe Plaque-type Psoriasis (PsO)

Phase 3

Active, not recruiting

Conditions: Plaque Psoriasis

Interventions: Drug: apremilast
Drug: Placebo

First Posted Date: 2023-11-08

Last Posted Date: 2025-03-13

Lead Sponsor: Amgen

Target Recruit Count: 203

Registration Number: NCT06122649

Locations: 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
🇨🇳
Peking University Third Hospital, Beijing, Beijing, China
🇨🇳
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

and more 18 locations

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

Phase 3

Recruiting

Conditions: Limited Stage Small Cell Lung Cancer
Small Cell Lung Cancer

Interventions: Drug: Tarlatamab
Drug: Placebo

First Posted Date: 2023-11-07

Last Posted Date: 2025-06-13

Lead Sponsor: Amgen

Target Recruit Count: 400

Registration Number: NCT06117774

Locations: 🇺🇸
Valkyrie Clinical Trials, Los Angeles, California, United States
🇺🇸
University of California Los Angeles, Santa Monica, California, United States
🇺🇸
Yale New Haven Hospital, New Haven, Connecticut, United States

and more 192 locations

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Phase 3

Recruiting

Conditions: Sjogren's Syndrome

Interventions: Drug: Dazodalibep
Drug: Placebo

First Posted Date: 2023-10-27

Last Posted Date: 2025-07-04

Lead Sponsor: Amgen

Target Recruit Count: 621

Registration Number: NCT06104124

Locations: 🇺🇸
Arizona Arthritis & Rheumatology Associates - Avondale, Avondale, Arizona, United States
🇺🇸
Arizona Research Clinic PLLC, Chandler, Arizona, United States
🇺🇸
Arizona Arthritis and Rheumatology Associates - Flagstaff - 399 S Malpais Ln, Flagstaff, Arizona, United States

and more 244 locations

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Phase 4

Recruiting

Conditions: Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Interventions: Drug: Avacopan
Drug: Placebo
Drug: Standard of Care

First Posted Date: 2023-10-10

Last Posted Date: 2025-06-26

Lead Sponsor: Amgen

Target Recruit Count: 300

Registration Number: NCT06072482

Locations: 🇺🇸
University of South Florida, Tampa, Florida, United States
🇺🇸
Orthopedic Physicians Alaska, Anchorage, Alaska, United States
🇺🇸
Scottsdale Healthcare at Shea - HonorHealth, Scottsdale, Arizona, United States

and more 39 locations

Tarlatamab (AMG 757) Expanded Access Protocol for Advanced Small Cell Lung Cancer

Conditions: Small Cell Lung Cancer

First Posted Date: 2023-10-03

Last Posted Date: 2025-03-10

Lead Sponsor: Amgen

Registration Number: NCT06064500

Locations: 🇮🇱
Hadassah University Hospital-Ein Kerem, Jerusalem, Israel
🇺🇸
Yale School of Medicine, New Haven, Connecticut, United States
🇺🇸
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States

and more 20 locations

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