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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Phase 1b Multicenter Study of Carfilzomib With Lenalidomide and Dexamethasone in Relapsed Multiple Myeloma

Phase 1
Completed
Conditions
Relapsed Multiple Myeloma
Interventions
First Posted Date
2008-01-29
Last Posted Date
2017-05-30
Lead Sponsor
Amgen
Target Recruit Count
84
Registration Number
NCT00603447
Locations
🇺🇸

Pacific Shores Medical Group, Long Beach, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

University of California San Francisco, San Francisco, California, United States

and more 9 locations

P3 Study to Evaluate Efficacy and Safety of AMG 531 in Thrombocytopenic Japanese Subjects With Immune (Idiopathic) Thrombocytopenic Purpura

Phase 3
Completed
Conditions
Idiopathic Thrombocytopenic Purpura
Interventions
Drug: Placebo
First Posted Date
2008-01-29
Last Posted Date
2022-11-08
Lead Sponsor
Amgen
Target Recruit Count
34
Registration Number
NCT00603642

Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy

Phase 2
Terminated
Conditions
Hepatic Encephalopathy
Interventions
Drug: placebo solution (10% dextrose)
Drug: sodium phenylacetate and sodium benzoate injection 10% / 10%
First Posted Date
2008-01-18
Last Posted Date
2024-12-17
Lead Sponsor
Amgen
Target Recruit Count
1
Registration Number
NCT00597909
Locations
🇺🇸

Permian Research Foundation, Odessa, Texas, United States

🇺🇸

UCSF-Fresno University, Fresno, California, United States

🇺🇸

Loma Linda University Medical Center, Loma Linda, California, United States

Phase 2 Study of AMG 386 (20060439) in Combination With Cisplatin & Capecitabine in Subjects With Metastatic Gastric, Gastroesophageal Junction, or Distal Esophageal Adenocarcinoma

Phase 2
Completed
Conditions
Gastrointestinal Cancer
Interventions
Drug: AMG 386 3mg/kg
Drug: AMG 386 placebo
Drug: AMG 386 10mg/kg
First Posted Date
2007-12-31
Last Posted Date
2014-05-07
Lead Sponsor
Amgen
Target Recruit Count
171
Registration Number
NCT00583674

Effect of Panitumumab on the Pharmacokinetics of Irinotecan

Phase 1
Completed
Conditions
Metastatic Colorectal Cancer
Interventions
First Posted Date
2007-11-26
Last Posted Date
2016-04-12
Lead Sponsor
Amgen
Target Recruit Count
28
Registration Number
NCT00563316
Locations
🇨🇦

Research Site, Toronto, Ontario, Canada

AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma

Phase 1
Completed
Conditions
Lymphoma
Prostate Cancer
Sarcoma
Unspecified Adult Solid Tumor, Protocol Specific
Small Intestine Cancer
First Posted Date
2007-11-22
Last Posted Date
2013-07-18
Lead Sponsor
Amgen
Target Recruit Count
64
Registration Number
NCT00562380
Locations
🇺🇸

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

Phase 3
Completed
Conditions
Breast Cancer
Interventions
Drug: Placebo
Biological: Denosumab
Other: Standard of Care
Drug: Non-steroidal aromatase inhibitor therapy
First Posted Date
2007-11-12
Last Posted Date
2023-07-27
Lead Sponsor
Amgen
Target Recruit Count
3420
Registration Number
NCT00556374
Locations
🇸🇪

Research Site, Uppsala, Sweden

Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders

Phase 2
Completed
Conditions
Urea Cycle Disorders
Interventions
First Posted Date
2007-10-30
Last Posted Date
2024-07-10
Lead Sponsor
Amgen
Target Recruit Count
14
Registration Number
NCT00551200
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

🇺🇸

Baylor College of Medicine, Houston, Texas, United States

Radiotherapy Plus Panitumumab Compared to Chemoradiotherapy With Unresected, Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Phase 2
Completed
Conditions
Cancer
Head and Neck Cancer
Oncology
Squamous Cell Carcinoma
Interventions
First Posted Date
2007-10-22
Last Posted Date
2017-03-15
Lead Sponsor
Amgen
Target Recruit Count
152
Registration Number
NCT00547157

A Phase II Study of CCX282-B in Patients With Celiac Disease

Phase 2
Completed
Conditions
Celiac Disease
Interventions
Drug: Placebo
First Posted Date
2007-10-08
Last Posted Date
2025-03-06
Lead Sponsor
Amgen
Target Recruit Count
90
Registration Number
NCT00540657
Locations
🇫🇮

Finn-Medi Research Ltd, Outpatient Clinic, Tampere, Finland

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