DeepMed Research

UNIVERSITY COLLEGE LONDON

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1826-02-11

Employees: 10K

Market Cap: -

Website: http://www.ucl.ac.uk

Clinical Trials

Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma

Phase 2

Terminated

Conditions: Glioblastoma

Interventions: Drug: cediranib maleate
Drug: Placebo
Drug: gefitinib

First Posted Date: 2011-03-09

Last Posted Date: 2017-05-31

Lead Sponsor: University College, London

Target Recruit Count: 38

Registration Number: NCT01310855

Locations: 🇬🇧
Bristol Haematology and Oncology Centre, Bristol, United Kingdom
🇬🇧
Southampton General Hospital, Southampton, United Kingdom
🇬🇧
Royal Marsden Hospital, Sutton, United Kingdom

and more 7 locations

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

Phase 2

Completed

Conditions: Glioblastoma

Interventions: Drug: 5-ALA
Drug: Gliadel wafers
Radiation: Radiotherapy as normal based on standard clinical protocols determined by the neuro-oncologist
Drug: Concomitant chemotherapy as normal based on standard clinical protocols determined by the neuro-oncologist
Drug: Adjuvant chemotherapy as normal based on standard clinical protocols determined by the neuro-oncologist

First Posted Date: 2011-03-09

Last Posted Date: 2017-10-05

Lead Sponsor: University College, London

Target Recruit Count: 59

Registration Number: NCT01310868

Locations: 🇬🇧
Royal Preston Hospital, Preston, Lancashire, United Kingdom
🇬🇧
Leeds General Infirmary, Leeds, United Kingdom
🇬🇧
Ninewells Hospital, Dundee, United Kingdom

and more 7 locations

Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery

Phase 3

Completed

Conditions: Coronary Heart Disease

Interventions: Procedure: Control
Procedure: Remote ischaemic preconditioning

First Posted Date: 2010-11-24

Last Posted Date: 2015-05-29

Lead Sponsor: University College, London

Target Recruit Count: 1612

Registration Number: NCT01247545

Locations: 🇬🇧
Royal Sussex County Hospital, Brighton, Sussex, United Kingdom
🇬🇧
Papworth Hospital, Cambridge, United Kingdom
🇬🇧
Blackpool Victoria Hospital, Blackpool, United Kingdom

and more 25 locations

ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancer

Phase 1

Completed

Conditions: Biliary Tract Neoplasms
Cholangiocarcinoma
Gallbladder Neoplasms

Interventions: Drug: selumetinib
Drug: gemcitabine
Drug: cisplatin

First Posted Date: 2010-11-17

Last Posted Date: 2016-05-13

Lead Sponsor: University College, London

Target Recruit Count: 13

Registration Number: NCT01242605

Locations: 🇬🇧
University College London Hospital, London, United Kingdom
🇬🇧
Hammersmith Hospital, London, United Kingdom
🇬🇧
The Christie Hospital, Manchester, United Kingdom

MACS Study - Microparticles and Coagulation in Sickle Cell Disease

Conditions: Sickle Cell Disease

First Posted Date: 2010-11-17

Last Posted Date: 2010-11-18

Lead Sponsor: University College, London

Target Recruit Count: 360

Registration Number: NCT01242878

Locations: 🇬🇧
Whittington Hospital NHS Trust, London, United Kingdom
🇬🇧
University College London Hospitals NHS Foundation Trust, London, United Kingdom
🇬🇧
Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

Depression and Anxiety in the Aetiology and Prognosis of Specific Cardiovascular Disease Syndromes: a CALIBER Study

Conditions: Depression
Anxiety
Coronary Disease
Cardiovascular Disease

First Posted Date: 2010-11-15

Last Posted Date: 2010-11-23

Lead Sponsor: University College, London

Registration Number: NCT01240798

Locations: 🇬🇧
Clinical Epidemiology Group, University College London, London, United Kingdom

Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers

Phase 2

Conditions: Lymphoma
Graft Versus Host Disease
Leukemia
Myeloma
Myelodysplastic Syndrome

Interventions: Other: No DLI
Other: CD4 DLI

First Posted Date: 2010-11-15

Last Posted Date: 2019-02-12

Lead Sponsor: University College, London

Target Recruit Count: 114

Registration Number: NCT01240525

Locations: 🇬🇧
Birmingham Heartlands Hospital, Birmingham, United Kingdom
🇬🇧
Bristol Royal Hospital for Children, Bristol, United Kingdom
🇬🇧
Addenbrooke's Hospital, Cambridge, United Kingdom

and more 8 locations

Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer

Phase 2

Completed

Conditions: Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer

Interventions: Drug: Paclitaxel
Drug: Saracatinib
Drug: Matched placebo

First Posted Date: 2010-09-08

Last Posted Date: 2015-05-05

Lead Sponsor: University College, London

Target Recruit Count: 107

Registration Number: NCT01196741

Locations: 🇬🇧
St Bartholomew's Hospital, London, Greater London, United Kingdom
🇬🇧
The Christie NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
🇬🇧
University College London Hospital, London, Greater London, United Kingdom

and more 9 locations

CD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL)

Phase 1

Terminated

Conditions: Acute Lymphoblastic Leukemia

Interventions: Genetic: donor-derived EBV-specific cytotoxic T-cells (EBV-CTL) transduced with the retroviral vector SFGalpha-CD19-CD3zeta
Biological: Irradiated donor-derived Lymphoblastoid Cell Line

First Posted Date: 2010-09-06

Last Posted Date: 2018-05-17

Lead Sponsor: University College, London

Target Recruit Count: 29

Registration Number: NCT01195480

Locations: 🇩🇪
Medizinische Hochschule, Hannover, Germany
🇬🇧
University College London Hospital, London, United Kingdom
🇩🇪
Hospital for Children and Adolescents III, Goethe University, Frankfurt, Germany

and more 4 locations

Focal Therapy for Prostate Cancer Using HIFU

Not Applicable

Recruiting

Conditions: Male Erectile Disorder
Therapy-related Toxicity
Prostate Cancer
Urinary Incontinence

Interventions: Other: questionnaire administration
Procedure: assessment of therapy complications
Procedure: high-intensity focused ultrasound ablation
Procedure: multiparametric magnetic resonance imaging
Procedure: quality-of-life assessment
Procedure: transperineal prostate biopsy
Procedure: transrectal prostate biopsy

First Posted Date: 2010-09-03

Last Posted Date: 2018-04-20

Lead Sponsor: University College, London

Target Recruit Count: 354

Registration Number: NCT01194648

Locations: 🇬🇧
University College London, London, England, United Kingdom

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