MedPath

Commons, Marty

🇺🇸United States
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Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: CSJ117
Drug: Placebo
First Posted Date
2021-05-11
Last Posted Date
2022-11-28
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
38
Registration Number
NCT04882124
Locations
🇯🇵

Novartis Investigative Site, Naka-gun, Ibaraki, Japan

A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab

Phase 4
Terminated
Conditions
Relapsing Multiple Sclerosis (RMS)
Interventions
Drug: Ofatumumab
Biological: mRNA COVID-19 vaccine
Drug: interferon or glatiramer acetate
First Posted Date
2021-05-07
Last Posted Date
2024-06-20
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT04878211
Locations
🇺🇸

Dragonfly Research LLC, Wellesley, Massachusetts, United States

🇺🇸

Minnesota Center Multiple Sclerosis, Plymouth, Minnesota, United States

🇺🇸

The MS Center for Innovation in Care, Saint Louis, Missouri, United States

and more 4 locations

STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

Phase 2
Completed
Conditions
Myelodysplastic Syndrome (MDS)
Interventions
Drug: MBG453
Drug: Azacitidine
Drug: Decitabine
Drug: INQOVI (oral decitabine)
First Posted Date
2021-05-07
Last Posted Date
2024-10-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
39
Registration Number
NCT04878432
Locations
🇺🇸

Duke Cancer Institute, Durham, North Carolina, United States

🇺🇸

University Hospitals Of Cleveland, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

and more 12 locations

Asciminib Roll-over Study

Phase 4
Recruiting
Conditions
Chronic Myelogenous Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions
First Posted Date
2021-05-07
Last Posted Date
2024-12-12
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
347
Registration Number
NCT04877522
Locations
🇺🇸

Michigan Med University of Michigan, Ann Arbor, Michigan, United States

🇺🇸

Memorial Sloan Kettering, New York, New York, United States

🇺🇸

Oregon Health Sciences University, Portland, Oregon, United States

and more 2 locations

Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome

Phase 3
Completed
Conditions
Acute Coronary Syndrome
Interventions
First Posted Date
2021-05-05
Last Posted Date
2024-12-27
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
400
Registration Number
NCT04873934
Locations
🇺🇸

Reliant Medical Research, Miami, Florida, United States

🇺🇸

Meridian Clinical Research, Lincoln, Nebraska, United States

🇺🇸

Longwood Research, Huntsville, Alabama, United States

and more 92 locations

Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With Ofatumumab

Phase 4
Completed
Conditions
Relapsing Multiple Sclerosis
Interventions
First Posted Date
2021-05-03
Last Posted Date
2024-12-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
34
Registration Number
NCT04869358
Locations
🇩🇪

Novartis Investigative Site, Unterhaching, Germany

Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)

Phase 2
Completed
Conditions
Familial Cold Autoinflammatory Syndrome
Interventions
Drug: DFV890
First Posted Date
2021-05-03
Last Posted Date
2024-10-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
4
Registration Number
NCT04868968
Locations
🇩🇪

Novartis Investigative Site, Tuebingen, Germany

Study of Efficacy, Safety, and Tolerability of LNA043 in Patients With Knee Osteoarthritis

Phase 2
Active, not recruiting
Conditions
Osteoarthritis
Interventions
Drug: LNA043 Dosing Regimen A
Drug: LNA043 Dosing Regimen B
Drug: LNA043 Dosing Regimen C
Drug: LNA043 Dosing Regimen D
Drug: Placebo
First Posted Date
2021-04-28
Last Posted Date
2024-12-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
585
Registration Number
NCT04864392
Locations
🇺🇸

Elite Clinical Studies, Phoenix, Arizona, United States

🇺🇸

Tucson Orthopedic Institute PC, Tucson, Arizona, United States

🇺🇸

Clinical Trials Research, Lincoln, California, United States

and more 21 locations

Pilot Decentralized Clinical Trial in Men and Pre and Post-menopausal Women With Breast Cancer and a Specific Mutation (PIK3CA) Treated With Alpelisib in Combination With Fulvestrant

Phase 2
Terminated
Conditions
Advanced Breast Cancer
Interventions
First Posted Date
2021-04-27
Last Posted Date
2024-06-20
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
2
Registration Number
NCT04862143
Locations
🇸🇪

Novartis Investigative Site, Orebro, Sweden

A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

Phase 1
Recruiting
Conditions
Mesothelioma
Interventions
Drug: IAG933
First Posted Date
2021-04-23
Last Posted Date
2024-12-18
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
156
Registration Number
NCT04857372
Locations
🇺🇸

University of California LA, Los Angeles, California, United States

🇺🇸

Uni of Chi Medi Ctr Hema and Onco, Chicago, Illinois, United States

🇺🇸

Sidney Kimmel CCC At JH, Baltimore, Maryland, United States

and more 4 locations
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