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The Case Comprehensive Cancer Center

The Case Comprehensive Cancer Center logo
🇺🇸United States
Ownership
Subsidiary
Established
1826-01-01
Employees
5K
Market Cap
-
Website
http://www.case.edu/cancer

ASTX727 and Nivolumab in Squamous Cell Carcinoma of the Head and Neck

Phase 1
Withdrawn
Conditions
Recurrent Squamous Cell Carcinoma of the Head and Neck
Metastatic Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
Interventions
Drug: INQOVI (decitabine and cedazuridine)
First Posted Date
2024-04-10
Last Posted Date
2024-07-03
Lead Sponsor
Case Comprehensive Cancer Center
Registration Number
NCT06357858
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Not Applicable
Recruiting
Conditions
Somatic Mutation
Interventions
Other: Survey
Other: Biological specimen collection
Other: Communications about study updates and future research opportunities
Other: Qualitative interview
First Posted Date
2024-04-10
Last Posted Date
2024-12-04
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
500
Registration Number
NCT06357845
Locations
🇺🇸

Case Western Reserve University, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Reiki Therapy to Improve Key Symptoms in Integrative Oncology Clinic (REIKI)

Not Applicable
Recruiting
Conditions
Cancer Pain
Oncology Pain
Interventions
Other: Reiki
First Posted Date
2024-04-09
Last Posted Date
2025-01-22
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
20
Registration Number
NCT06354049
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Not Applicable
Recruiting
Conditions
Moderate Depression
Breast Cancer Female
Breast Cancer Stage I
Breast Cancer
Breast Cancer Stage II
Breast Cancer Stage III
Mild Depression
Interventions
Other: MBCT
First Posted Date
2024-03-28
Last Posted Date
2025-05-25
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
31
Registration Number
NCT06336538
Locations
🇺🇸

Cleveland Clinic Department of Wellness and Preventive Medicine, Cleveland, Ohio, United States

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

Phase 2
Not yet recruiting
Conditions
Malignant Neoplasm of Bladder
Muscle Invasive Bladder Carcinoma
Interventions
Drug: Neoadjuvant Chemotherapy
Procedure: Partial cystectomy with Extended pelvic lymph node dissection
Drug: Adjuvant systemic therapy
First Posted Date
2024-03-04
Last Posted Date
2025-05-14
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
40
Registration Number
NCT06290687
Locations
🇺🇸

Glickman Urological and Kidney Institute, Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Not Applicable
Recruiting
Conditions
Gastrointestinal Cancer
Anal Cancer
Esophageal Cancer
Appendix Cancer
Liver Cancer
Stomach Cancer
Rectal Cancer
Pancreas Cancer
Colon Cancer
Neuroendocrine Tumors
Interventions
Other: EQUITY GI
First Posted Date
2024-02-16
Last Posted Date
2025-05-07
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
200
Registration Number
NCT06263088
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

Not Applicable
Recruiting
Conditions
Urothelial Carcinoma
Interventions
Procedure: Nephroureterectomy
Procedure: Lymph Node Dissection
First Posted Date
2024-02-16
Last Posted Date
2025-07-02
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
94
Registration Number
NCT06262516
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Urology Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic Glickman Urological and Kidney Institute, Cleveland, Ohio, United States

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

Not Applicable
Recruiting
Conditions
Skin Cancer
Skin Carcinoma
Interventions
Other: Water
Other: Lavender essential oil
First Posted Date
2023-12-12
Last Posted Date
2025-04-24
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
100
Registration Number
NCT06167096
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Phase 2
Recruiting
Conditions
Prostate Cancer
Secondary Malignant Neoplasm of Prostate
Malignant Neoplasm of Prostate
Interventions
Drug: Androgen deprivation therapy (ADT)
Drug: Androgen receptor signaling inhibitor (ARSI)
Radiation: Metastasis directed radiotherapy (MDRT)
First Posted Date
2023-11-29
Last Posted Date
2025-06-29
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
200
Registration Number
NCT06150417
Locations
🇺🇸

University Hospitals Cleveland Medical Center Seidman Cancer Center, Cleveland, Ohio, United States

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Phase 2
Recruiting
Conditions
Tumor, Breast
Breast Cancer
Interventions
Radiation: Radiation Therapy
First Posted Date
2023-11-13
Last Posted Date
2024-12-13
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
55
Registration Number
NCT06129747
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

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