The Case Comprehensive Cancer Center

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary

Established: 1826-01-01

Employees: 5K

Market Cap: -

Website: http://www.case.edu/cancer

Clinical Trials

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)

Phase 2

Not yet recruiting

Conditions: Pseudomyxoma Peritonei
Secondary Malignant Neoplasm of Peritoneum
Secondary Malignant Neoplasm of Retroperitoneum

Interventions: Procedure: Intestinal, Multivisceral or Modified Multivisceral Transplantation
Drug: Alemtuzumab
Drug: Tacrolimus
Drug: Sirolimus

First Posted Date: 2023-10-16

Last Posted Date: 2025-03-25

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 20

Registration Number: NCT06084780

Locations: 🇺🇸
Cleveland Clinic Digestive Disease & Surgery Institute (DDSI), Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses

Phase 2

Active, not recruiting

Conditions: Actinic Keratosis

Interventions: Drug: Topical aminolevulinate (10% ALA gel)
Device: Red light illumination

First Posted Date: 2023-09-07

Last Posted Date: 2025-05-14

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 30

Registration Number: NCT06027619

Locations: 🇺🇸
Cleveland Clinic, Dermatology and Plastic Surgery Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Individualized Treatments in Adults With Relapsed/Refractory Cancers

Not Applicable

Recruiting

Conditions: Refractory Cancer
Relapsed Cancer

Interventions: Diagnostic Test: Drug Sensitivity Test (DST)

First Posted Date: 2023-09-06

Last Posted Date: 2024-07-11

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 36

Registration Number: NCT06024603

Locations: 🇺🇸
Florida International University, Miami, Florida, United States
🇺🇸
Lerner College of Medicine, Cleveland Clinic Florida, Weston, Florida, United States

NAVAH Impact on Radiation Therapy Completion in Black Breast & Prostate Cancer Patients

Not Applicable

Recruiting

Conditions: Breast Cancer
Prostate Cancer

Interventions: Behavioral: NAVAH

First Posted Date: 2023-08-07

Last Posted Date: 2024-11-14

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 200

Registration Number: NCT05978232

Locations: 🇺🇸
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients

Not Applicable

Not yet recruiting

Conditions: Node-positive Breast Cancer

Interventions: Procedure: Axillary Lymph Node Dissection
Procedure: Axillary Reverse Mapping
Procedure: Lymphaticovenous Bypass

First Posted Date: 2023-08-01

Last Posted Date: 2025-04-20

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 400

Registration Number: NCT05970107

Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses

Phase 2

Recruiting

Conditions: Actinic Keratoses

Interventions: Drug: Topical Aminolevulinate
Procedure: Photodynamic therapy (PDT)
Procedure: Red light illumination

First Posted Date: 2023-06-28

Last Posted Date: 2024-10-29

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 20

Registration Number: NCT05923060

Locations: 🇺🇸
Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Early Detection of Multiple Myeloma to Fight Cancer Disparities: A Screening and Patient Navigation Program

Not Applicable

Active, not recruiting

Conditions: Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance
Smoldering Multiple Myeloma

Interventions: Other: Multiple Myeloma M-Protein Analysis
Other: Multiple Myeloma Knowledge Questionnaires

First Posted Date: 2023-04-26

Last Posted Date: 2025-03-26

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 201

Registration Number: NCT05831358

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®

Not Applicable

Recruiting

Conditions: Breast Cancer

Interventions: Procedure: Arm 1 Partial mastectomy with Savi Scout® localization and shave margins.
Procedure: Arm 2 Partial mastectomy with Savi Scout® localization and selective shave margins.

First Posted Date: 2023-04-24

Last Posted Date: 2024-08-27

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 204

Registration Number: NCT05825482

Locations: 🇺🇸
Cleveland Clinic Akron General, Case Comprehensive Cancer Center, Akron, Ohio, United States

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Phase 2

Terminated

Conditions: Pancreatic Fistula

Interventions: Drug: Piperacillin/Tazobactam
Drug: Amoxicillin/ Clavulanic acid

First Posted Date: 2023-03-03

Last Posted Date: 2024-08-05

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 3

Registration Number: NCT05753735

Locations: 🇺🇸
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy

Not Applicable

Recruiting

Conditions: Renal Cell Carcinoma

Interventions: Procedure: Donor Radical and Partial Nephrectomy
Procedure: Kidney Transplantation
Procedure: Laparoscopic Radical Nephrectomy

First Posted Date: 2023-02-13

Last Posted Date: 2025-05-14

Lead Sponsor: Case Comprehensive Cancer Center

Target Recruit Count: 5

Registration Number: NCT05725421

Locations: 🇺🇸
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

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