DeepMed Research

TASK Applied Science

🇿🇦South Africa

Country: 🇿🇦South Africa

Ownership: Private

Established: 2005-01-01

Employees: -

Market Cap: -

Website: https://www.task.org.za/

Clinical Trials

A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination with Ethionamide

Phase 2

Recruiting

Conditions: Tuberculosis

Interventions: Drug: Alpibectir 45 mg once daily (OD) plus Ethionamide 125 mg OD
Drug: Alpibectir 45 mg OD plus Ethionamide 250 mg OD
Drug: Isoniazid, rifampicin, pyrazinamide and ethambutol fixed dose combination, weight based
Drug: Alpibectir 45 mg OD plus Ethionamide 250 mg OD plus Rifampicin 10 mg/kg OD plus Ethambutol 20 mg/kg OD plus Pyrazinamide 25 mg/kg OD

First Posted Date: 2024-12-27

Last Posted Date: 2025-03-07

Lead Sponsor: TASK Applied Science

Target Recruit Count: 60

Registration Number: NCT06748937

Locations: 🇿🇦
TASK, Cape Town, Western Cape, South Africa

Study to Evaluate EBA, Safety and Tolerability of Carbapenems in Adults With Pulmonary Tuberculosis

Phase 2

Completed

Conditions: Pulmonary Tuberculosis

Interventions: Drug: Ertapenem 1g IM
Drug: Meropenem 3g IV
Drug: Ertapenem 1g IV
Drug: Meropenem 6g IV over 60 minutes
Drug: Rifafour e-275
Drug: Meropenem 6g IV over 6 hours
Drug: Amoxicillin/CA twice daily
Drug: Rifampicin 35 mg/kg
Drug: Meropenem 4g IV
Drug: Amoxicillin/CA once daily

First Posted Date: 2023-06-09

Last Posted Date: 2023-06-09

Lead Sponsor: TASK Applied Science

Target Recruit Count: 134

Registration Number: NCT05896930

Locations: 🇿🇦
TASK Clinical Research Centre, Cape Town, Western Cape, South Africa

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098

Phase 2

Completed

Conditions: Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

Interventions: Drug: Ethionamide 250 mg
Drug: BVL-GSK098 9mg
Drug: Isoniazid 300 MG
Drug: Ethionamide 250mg

First Posted Date: 2022-07-25

Last Posted Date: 2025-02-20

Lead Sponsor: TASK Applied Science

Target Recruit Count: 106

Registration Number: NCT05473195

Locations: 🇿🇦
TASK Clinical Research Centre, Cape Town, Western Cape, South Africa

EBA, Safety and Tolerability of Sanfetrinem Cilexetil

Phase 2

Completed

Conditions: Tuberculosis, Pulmonary

Interventions: Drug: Sanfetrinem Cilexetil
Drug: Rifampicin

First Posted Date: 2022-05-24

Last Posted Date: 2025-02-21

Lead Sponsor: TASK Applied Science

Target Recruit Count: 54

Registration Number: NCT05388448

Locations: 🇿🇦
TASK Clinical Research Centre, Cape Town, Western Cape, South Africa

Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB

Phase 2

Completed

Conditions: Tuberculosis

Interventions: Drug: Meropenem Injection
Drug: Rifafour
Drug: Amoxicillin Clavulanate
Drug: Pyrazinamide
Drug: Bedaquiline

First Posted Date: 2020-11-16

Last Posted Date: 2022-01-25

Lead Sponsor: TASK Applied Science

Target Recruit Count: 22

Registration Number: NCT04629378

Locations: 🇿🇦
TASK Clinical Research Centre, Cape Town, Western Cape, South Africa

BCG Vaccination for Healthcare Workers in COVID-19 Pandemic

Phase 3

Completed

Conditions: Sars-CoV2
COVID-19

Interventions: Biological: Bacille Calmette-Guérin (BCG)
Other: Placebo Comparator

First Posted Date: 2020-05-07

Last Posted Date: 2022-01-25

Lead Sponsor: TASK Applied Science

Target Recruit Count: 1000

Registration Number: NCT04379336

Locations: 🇿🇦
TASK Foundation, Cape Town, Western Cape, South Africa

Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis

Phase 2

Completed

Conditions: Pulmonary Tuberculosis

Interventions: Drug: Rifafour e275
Drug: Meropenem
Drug: Faropenem
Drug: Amoxycillin/clavulanic acid

First Posted Date: 2015-01-29

Last Posted Date: 2018-09-13

Lead Sponsor: TASK Applied Science

Target Recruit Count: 46

Registration Number: NCT02349841

Locations: 🇿🇦
TASK Foundation NPC, Cape Town, Western Cape, South Africa

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