MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

EVOC - EVs in Obesity and Cardiometabolic Disease

Active, not recruiting

Conditions: Cardiovascular Diseases

First Posted Date: 2024-05-10

Last Posted Date: 2024-06-05

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 80

Registration Number: NCT06408961

Locations: 🇺🇸
Massachusetts General Hospita;, Boston, Massachusetts, United States

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

Phase 2

Recruiting

Conditions: Drug Allergy
Cephalosporin Allergy
Drug Hypersensitivity
Antibiotic Allergy
Beta Lactam Adverse Reaction
Drug-Induced Anaphylaxis
Cephalosporin Reaction

Interventions: Drug: Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing
Drug: Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge
Drug: Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge
Drug: Dissimilar cephalosporin (ceftriaxone or cefazolin) antibiotic double-blind placebo-controlled drug challenge
Drug: Amoxicillin double-blind placebo-controlled drug challenge

First Posted Date: 2024-05-09

Last Posted Date: 2025-05-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 300

Registration Number: NCT06406114

Locations: 🇺🇸
Mayo Clinic Arizona, Scottsdale, Arizona, United States
🇺🇸
University of California, San Francisco, San Francisco, California, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

and more 3 locations

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

Not Applicable

Recruiting

Conditions: Cannabis Use Disorder
Alcohol Use Disorder

Interventions: Behavioral: MET/CBT
Behavioral: InTEGRA

First Posted Date: 2024-05-02

Last Posted Date: 2025-04-27

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 294

Registration Number: NCT06395467

Locations: 🇺🇸
UConn Health, Farmington, Connecticut, United States
🇺🇸
MGH Department of Psychiatry, Boston, Massachusetts, United States

Pilot Randomized Clinical Trial of Change My Story

Not Applicable

Not yet recruiting

Conditions: Hiv
Psychological Distress
Depression

Interventions: Behavioral: Problem Solving Therapy
Other: Change My Story

First Posted Date: 2024-04-29

Last Posted Date: 2024-04-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 80

Registration Number: NCT06389565

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

Not Applicable

Recruiting

Conditions: Schizophrenia

Interventions: Other: Closed loop auditory stimulation during sleep

First Posted Date: 2024-04-26

Last Posted Date: 2025-05-14

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT06386588

Locations: 🇺🇸
Massachusetts General Hospital, Charlestown, Massachusetts, United States

PET/MRI for Evaluation of Endometriosis

Not yet recruiting

Conditions: Endometriosis
Endometrioma

Interventions: Drug: Radiotracer Injection
Diagnostic Test: Imaging
Other: Rectal Ultrasound Gel Injection

First Posted Date: 2024-04-22

Last Posted Date: 2024-04-22

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT06377553

Locations: 🇺🇸
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, United States