MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Effects of Newly-Initiated QUAD Therapy on Aortic/Coronary Inflammation in ART-Naïve Infected Patients

Completed

Conditions: HIV

First Posted Date: 2013-01-11

Last Posted Date: 2017-03-17

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 33

Registration Number: NCT01766726

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Efficacy Study of a Novel Device to Clean the Endotracheal Tube

Not Applicable

Completed

Conditions: Endotracheal Extubation
Airway Obstruction
Airway Control
Pneumonia, Ventilator-Associated
Breathing Mechanics

Interventions: Device: ETT cleaning maneuver

First Posted Date: 2013-01-10

Last Posted Date: 2017-10-18

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 74

Registration Number: NCT01765530

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder

Not Applicable

Completed

Conditions: Sleep Problems
Bipolar Disorder
Insomnia
Hypersomnia

Interventions: Behavioral: Body Scan (BS) Meditation Intervention
Behavioral: Brief Supportive Psychotherapy (SP)

First Posted Date: 2013-01-09

Last Posted Date: 2016-06-24

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 48

Registration Number: NCT01764035

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Study of the Effect of Testosterone and Estradiol on NP Responses to Acute and Chronic Salt Loading

Early Phase 1

Withdrawn

Conditions: Hypertension

Interventions: Drug: leuprolide acetate
Drug: Anastrozole

First Posted Date: 2013-01-09

Last Posted Date: 2017-10-19

Lead Sponsor: Massachusetts General Hospital

Registration Number: NCT01763541

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Brief Sleep Intervention for Bipolar Disorder

Not Applicable

Completed

Conditions: Bipolar Disorder
Suicidal Thoughts
Sleep Problems

Interventions: Behavioral: Brief Sleep Intervention

First Posted Date: 2013-01-09

Last Posted Date: 2019-03-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT01764074

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas

Not Applicable

Completed

Conditions: Type 1 Diabetes

Interventions: Other: Usual care
Device: Bi-homonal Bionic Pancreas

First Posted Date: 2013-01-07

Last Posted Date: 2017-07-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 32

Registration Number: NCT01762059

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans

Phase 1

Active, not recruiting

Conditions: Diabetes Mellitus, Type 2

Interventions: Drug: Glipizide
Drug: Metformin
Other: Oral Glucose Tolerance Test

First Posted Date: 2013-01-07

Last Posted Date: 2025-05-08

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 1033

Registration Number: NCT01762046

Locations: 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Joslin Diabetes Center, Boston, Massachusetts, United States

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

Not Applicable

Recruiting

Conditions: Chronic Kidney Disease
Multiple Myeloma
Acute Myeloid Leukemia (AML)
Chronic Myelogenous Leukemia (CML)
Aplastic Anemia
AL Amyloidosis
Chronic Lymphocytic Leukemia (CLL)
Non-Hodgkin's Lymphoma (NHL)
Myelodysplastic Syndrome (MDS)
Myelofibrosis

Interventions: Procedure: Haploidentical Bone Marrow/Kidney

First Posted Date: 2012-12-31

Last Posted Date: 2023-03-15

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 10

Registration Number: NCT01758042

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma

Phase 2

Terminated

Conditions: Melanoma

Interventions: Drug: Aldesleukin
Drug: Vemurafenib

First Posted Date: 2012-12-21

Last Posted Date: 2017-04-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 6

Registration Number: NCT01754376

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

AUY922 for Advanced ALK-positive NSCLC

Phase 2

Completed

Conditions: Non Small Cell Lung Cancer

Interventions: Drug: AUY922

First Posted Date: 2012-12-19

Last Posted Date: 2018-03-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 6

Registration Number: NCT01752400

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸
Beth Isreal Deaconess Medical Center, Boston, Massachusetts, United States

and more 1 locations

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