MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury

Phase 1

Active, not recruiting

Conditions: Demyelinating Disorder
Brain Injuries, Traumatic
Alzheimer Disease

Interventions: Drug: F18-3F4AP

First Posted Date: 2021-01-14

Last Posted Date: 2024-01-30

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 8

Registration Number: NCT04710550

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia

Phase 4

Completed

Conditions: Restless Legs Syndrome
Insomnia
Sleep Disorder

Interventions: Drug: Suvorexant
Other: Placebo

First Posted Date: 2021-01-12

Last Posted Date: 2024-01-16

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 46

Registration Number: NCT04706091

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Development and Implementation of Electronic Decision Aids for Genetic Testing in Inherited Cancer Syndromes

Not Applicable

Completed

Conditions: Genetic Testing

Interventions: Other: Survey of Decision Aid

First Posted Date: 2021-01-11

Last Posted Date: 2024-08-13

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 93

Registration Number: NCT04704193

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Phase 2

Recruiting

Conditions: Metastatic Urothelial Carcinoma
Bladder Cancer

Interventions: Drug: Pembrolizumab
Procedure: Cryoablation
Drug: Avelumab

First Posted Date: 2021-01-08

Last Posted Date: 2024-04-16

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 30

Registration Number: NCT04701918

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects

Phase 1

Recruiting

Conditions: Multiple Sclerosis

Interventions: Drug: F-18 3F4AP

First Posted Date: 2021-01-07

Last Posted Date: 2025-02-27

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 60

Registration Number: NCT04699747

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Family Intervention to Improve Maternal and Child Mental Health

Not Applicable

Conditions: Adolescent Pregnancy

Interventions: Behavioral: Virtual perinatal home visiting

First Posted Date: 2021-01-07

Last Posted Date: 2022-06-09

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 300

Registration Number: NCT04700059

Locations: 🇵🇪
Instituto Nacional Materno Perinatal, Lima, Peru

Prognostication of Recovery in Early Disorders of Consciousness Study

Not yet recruiting

Conditions: Disorders of Consciousness Due to Severe Brain Injury

Interventions: Diagnostic Test: MRI
Diagnostic Test: EEG

First Posted Date: 2021-01-05

Last Posted Date: 2024-08-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 50

Registration Number: NCT04692922

Hospital at Home at EOL in Heme Malignancies

Not Applicable

Completed

Conditions: Hematologic Malignancy

Interventions: Other: End of Life (EOL) Care at at Home

First Posted Date: 2020-12-30

Last Posted Date: 2024-08-13

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 72

Registration Number: NCT04690205

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Portable Ultrasound for Interventional Procedures

Conditions: Ultrasound Therapy; Complications

Interventions: Procedure: Ultrasound guided procedure
Device: Portable ultrasound

First Posted Date: 2020-12-28

Last Posted Date: 2020-12-28

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 200

Registration Number: NCT04685330

A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)

Not Applicable

Completed

Conditions: Nondaily Smoking

Interventions: Behavioral: Smartphone app "Smiling instead of Smoking" (SiS) Version 3
Behavioral: Smartphone app "QuitGuide" (QG)
Behavioral: Brochure "Clearing the Air" (CTA)

First Posted Date: 2020-12-17

Last Posted Date: 2023-01-18

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 228

Registration Number: NCT04672239

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

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