MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study

Completed

Conditions: Williams Syndrome
Lipedema

First Posted Date: 2018-11-29

Last Posted Date: 2023-10-19

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 144

Registration Number: NCT03758651

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)

Phase 4

Completed

Conditions: Autism
Autism Spectrum Disorder
Non-verbal Learning Disorder

Interventions: Drug: Open-label Treatment with Omega-3 Fatty Acids + Inositol
Drug: Open-label Treatment with N-acetylcysteine

First Posted Date: 2018-11-29

Last Posted Date: 2025-06-05

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 54

Registration Number: NCT03757585

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Development of an Intervention to Enhance Cancer Pain Management

Not Applicable

Conditions: Other Cancer

Interventions: Behavioral: Enhancing Cancer Pain Management

First Posted Date: 2018-11-23

Last Posted Date: 2021-05-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 150

Registration Number: NCT03752268

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

A Study of the Role of Circulating Tumor DNA in Predicting the Likelihood of Organ Preservation After Clinical Complete Response to Neoadjuvant Therapy for Rectal Cancer

Withdrawn

Conditions: Gastrointestinal Malignancies

Interventions: Other: The Functional Assessment of Cancer Therapy- Colorectal

First Posted Date: 2018-11-21

Last Posted Date: 2019-07-08

Lead Sponsor: Massachusetts General Hospital

Registration Number: NCT03749083

Locations: 🇺🇸
Brigham and Women Hospital, Boston, Massachusetts, United States
🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Newton-Wellesley Hospital, Newton, Massachusetts, United States

and more 1 locations

Comparative Effectiveness of Pharmacogenomics for Treatment of Depression

Not Applicable

Completed

Conditions: Major Depressive Disorder

Interventions: Other: GeneSight Psychotropic test
Other: Canadian Network for Mood and Anxiety Treatment (CANMAT) Best Practice Guidelines

First Posted Date: 2018-11-21

Last Posted Date: 2022-04-07

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 201

Registration Number: NCT03749629

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Calcitriol Monotherapy for X-Linked Hypophosphatemia

Early Phase 1

Recruiting

Conditions: X-linked Hypophosphatemia
Hypophosphatemic Rickets, X-Linked Dominant
Hypophosphatemic Rickets

Interventions: Drug: Calcitriol

First Posted Date: 2018-11-21

Last Posted Date: 2024-03-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 20

Registration Number: NCT03748966

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder

Early Phase 1

Recruiting

Conditions: Major Depressive Disorder
Bipolar Depression

Interventions: Drug: Nitrogen gas
Drug: Xenon

First Posted Date: 2018-11-20

Last Posted Date: 2025-05-18

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 20

Registration Number: NCT03748446

Locations: 🇺🇸
Dauten Family Center for Bipolar Treatment Innovation, Boston, Massachusetts, United States

Effects of Nitric Oxide on the Endothelium During Hemolysis.

Phase 2

Recruiting

Conditions: Cardiovascular Risk Factor
Endothelial Dysfunction
Cardiovascular Diseases
Hemolysis Intravascular

Interventions: Diagnostic Test: Reactive Hyperemia Index
Drug: Nitric Oxide
Procedure: Endothelial Cells Collection

First Posted Date: 2018-11-20

Last Posted Date: 2022-11-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 40

Registration Number: NCT03748082

Locations: 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

The Role of Estrogen in the Neurobiology of Eating Disorders

Phase 2

Recruiting

Conditions: Eating Disorders
Hypoestrogenemia

Interventions: Drug: 17-β estradiol transdermal patches with cyclic progesterone
Drug: Placebo patch and pill

First Posted Date: 2018-11-14

Last Posted Date: 2025-05-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 120

Registration Number: NCT03740204

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy

Not Applicable

Completed

Conditions: Cognitive Change

Interventions: Device: Transcranial Light Therapy

First Posted Date: 2018-11-14

Last Posted Date: 2020-11-19

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 10

Registration Number: NCT03740152

Locations: 🇺🇸
Massachusetts General Hospital- Center for Anxiety and Traumatic Stress Disorders, Boston, Massachusetts, United States

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