MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma

Phase 1

Withdrawn

Conditions: Multiple Myeloma

Interventions: Drug: ABI-009
Drug: Pomalidomide
Drug: Dexamethasone

First Posted Date: 2018-09-05

Last Posted Date: 2019-08-14

Lead Sponsor: Massachusetts General Hospital

Registration Number: NCT03657420

Locations: 🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Focused Ultrasound Neuromodulation for Treatment of Temporal Lobe Epilepsy

Not Applicable

Withdrawn

Conditions: Low Intensity Ultrasound Pulsarions

Interventions: Device: BX Pulsar 1002

First Posted Date: 2018-09-04

Last Posted Date: 2023-03-16

Lead Sponsor: Massachusetts General Hospital

Registration Number: NCT03657056

Measuring Beliefs and Norms About Persons With Mental Illness

Not Applicable

Completed

Conditions: Mental Illness
Schizophrenia
Depression
Bipolar Disorder

Interventions: Other: Survey questionnaire

First Posted Date: 2018-09-04

Last Posted Date: 2019-08-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 1782

Registration Number: NCT03656770

Locations: 🇺🇬
Mbarara University of Science and Technology, Mbarara, Uganda

Using Imaging to Assess Effects of THC on Brain Activity

Not Applicable

Completed

Conditions: Intoxication Alcohol
Intoxication THC
Intoxication Combined Alcohol THC

Interventions: Drug: Dronabinol
Drug: Ethanol
Drug: Placebo dronabinol
Drug: Placebo ethanol

First Posted Date: 2018-08-31

Last Posted Date: 2022-07-28

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 316

Registration Number: NCT03655717

Locations: 🇺🇸
Center for Addiction Medicine, Massachusetts General Hospital, Dept. of Psychiatry, Boston, Massachusetts, United States

Propranolol Reactivation Mismatch (PRM) Treatment for PTSD

Phase 4

Conditions: Stress Disorders, Post-Traumatic

Interventions: Drug: Reactivation Mismatch

First Posted Date: 2018-08-29

Last Posted Date: 2018-08-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 11

Registration Number: NCT03652922

Inpatient Palliative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation

Not Applicable

Completed

Conditions: Stem Cell Transplant

Interventions: Other: Standard Transplant Care
Other: Palliative Care Intervention

First Posted Date: 2018-08-22

Last Posted Date: 2023-12-07

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 546

Registration Number: NCT03641378

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer.

Phase 1

Completed

Conditions: Oral Cancer

Interventions: Combination Product: Photodynamic Therapy

First Posted Date: 2018-08-20

Last Posted Date: 2021-02-21

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 30

Registration Number: NCT03638622

Locations: 🇮🇳
J.N. Medical College, Aligarh Muslim University, Aligarh, UP, India

Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant

Phase 4

Terminated

Conditions: Respiratory Failure
Hepatitis C

Interventions: Drug: Clinically prescribed direct acting antiviral (Mavyret or Epclusa) HCV treatment for 8 weeks

First Posted Date: 2018-08-10

Last Posted Date: 2023-04-25

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 19

Registration Number: NCT03625687

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Comparative Antiresorptive Efficacy Discontinuation of Denosumab

Phase 4

Active, not recruiting

Conditions: Osteoporosis
Osteoporosis, Postmenopausal

Interventions: Drug: denosumab
Drug: raloxifene
Drug: alendronate

First Posted Date: 2018-08-09

Last Posted Date: 2023-06-07

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 51

Registration Number: NCT03623633

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Preventing Depressive Relapse in Pregnant Women With Recurrent Depression

Not Applicable

Completed

Conditions: Pregnancy Related
Depression
Antenatal Depression

Interventions: Behavioral: Digital Delivery of Mindfulness-Based Cognitive Therapy

First Posted Date: 2018-08-09

Last Posted Date: 2023-06-06

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 500

Registration Number: NCT03623620

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
University of Colorado Boulder, Boulder, Colorado, United States

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