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CorMedix

🇺🇸United States
Ownership
-
Employees
83
Market Cap
$344.6M
Website

Clinical Trials

6

Active:0
Completed:2

Trial Phases

3 Phases

Phase 2:1
Phase 3:3
Phase 4:1

Drug Approvals

1

FDA:1

Drug Approvals

DEFENCATH

Approval Date
Dec 21, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials

Phase 3
3 (60.0%)
Phase 2
1 (20.0%)
Phase 4
1 (20.0%)

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

Phase 3
Recruiting
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
Drug: (taurolidine and heparin) catheter lock solution
First Posted Date
2025-02-12
Last Posted Date
2025-09-10
Lead Sponsor
CorMedix
Target Recruit Count
200
Registration Number
NCT06822426
Locations
🇺🇸

Johns Hopkins Clinical Research Unit, Baltimore, Maryland, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

and more 8 locations

Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

Phase 4
Recruiting
Conditions
Catheter-Related Infections
Interventions
Drug: (taurolidine and heparin) catheter lock solution
Drug: Standard of Care
First Posted Date
2024-12-04
Last Posted Date
2025-09-10
Lead Sponsor
CorMedix
Target Recruit Count
36
Registration Number
NCT06714864
Locations
🇺🇸

Children's of Alabama/University of Alabama, Birmingham, Alabama, United States

🇺🇸

Stanford, Palo Alto, California, United States

🇺🇸

Nemours Children's Hospital - DE, Wilmington, Delaware, United States

Expanded Access Program for Patients At Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials

Conditions
Catheter-related Bloodstream Infection
First Posted Date
2024-11-27
Last Posted Date
2024-11-27
Lead Sponsor
CorMedix
Registration Number
NCT06707480

Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection

Phase 3
Completed
Conditions
Kidney Failure, Chronic
Catheter-Related Infections
Interventions
First Posted Date
2016-01-11
Last Posted Date
2025-02-25
Lead Sponsor
CorMedix
Target Recruit Count
806
Registration Number
NCT02651428
Locations
🇺🇸

Riverside Nephrology Physicians/Van Buren Dialysis center, Riverside, California, United States

🇺🇸

North America Research Institute, San Dimas, California, United States

🇺🇸

North Beach Dialysis Center Inc., Miami Gardens, Florida, United States

and more 2 locations

Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent

Phase 3
Withdrawn
Conditions
Acute Kidney Injury
Interventions
Drug: Placebo
First Posted Date
2011-07-12
Last Posted Date
2020-08-24
Lead Sponsor
CorMedix
Registration Number
NCT01391520
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News

CorMedix Completes Phase III Enrollment for REZZAYO Antifungal Prophylaxis in Bone Marrow Transplant Patients

CorMedix announced completion of enrollment in the global Phase III ReSPECT trial evaluating REZZAYO (rezafungin) for preventing fungal infections in adult patients undergoing allogeneic blood and marrow transplantation.

CorMedix Makes $5 Million Strategic Investment in Talphera's Phase 3 Anticoagulant Program

CorMedix invested $5 million in Talphera as part of a $29 million private placement to fund completion of the Phase 3 NEPHRO CRRT study for Niyad, a breakthrough-designated anticoagulant.

CorMedix Acquires Melinta Therapeutics for $300 Million to Expand Anti-Infective Portfolio

CorMedix has entered a definitive agreement to acquire Melinta Therapeutics for $300 million, adding seven marketed infectious disease products to its portfolio.

CorMedix Announces Positive Preliminary Q4 2024 Results and Business Updates

CorMedix reported preliminary unaudited net revenue of approximately $31 million for Q4 2024 and $43 million for FY 2024, exceeding previous guidance.

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