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Pharmacyclics LLC

Pharmacyclics LLC logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Subsidiary
Established
1991-01-01
Employees
607
Market Cap
-
Website
http://www.pharmacyclics.com

A Multicenter Phase 2 Study of Ibrutinib in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) With 17p Deletion

Phase 2
Completed
Conditions
Chronic Lymphocytic Leukemia With 17p Deletion
Small Lymphocytic Lymphoma With 17p Deletion
Interventions
First Posted Date
2012-12-07
Last Posted Date
2017-02-27
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
145
Registration Number
NCT01744691

Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Phase 3
Completed
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2012-11-09
Last Posted Date
2023-09-21
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
232
Registration Number
NCT01724346
Locations
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Hospital Universitario HM Sanchinarro /ID# 1116-0537, Madrid, Spain

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Hospital Santa Creu i Sant Pau /ID# 1116-0535, Barcelona, Spain

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Gazi Universitesi Tip Fakultes /ID# 1116-0608, Yenimahalle, Ankara, Turkey

and more 85 locations

Open-label Phase 3 BTK Inhibitor Ibrutinib vs Chlorambucil Patients 65 Years or Older With Treatment-naive CLL or SLL

Phase 3
Completed
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2012-11-06
Last Posted Date
2017-11-30
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
269
Registration Number
NCT01722487
Locations
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Site Reference ID/Investigator #125, Atlanta, Georgia, United States

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Site Reference ID/Investigator #050, Pittsburgh, Pennsylvania, United States

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Site Reference ID/Investigator #032, Houston, Texas, United States

and more 105 locations

A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

Phase 3
Completed
Conditions
Relapsed or Refractory Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
First Posted Date
2012-04-17
Last Posted Date
2019-12-18
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
391
Registration Number
NCT01578707
Locations
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Site # 059, New Brunswick, New Jersey, United States

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Site # 501, Fitzroy, Victoria, Australia

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Site #408, La Jolla, California, United States

and more 73 locations

Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma

Phase 2
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2011-11-23
Last Posted Date
2020-03-10
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
92
Registration Number
NCT01478581
Locations
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SITE-5, Baltimore, Maryland, United States

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SITE-4, Boston, Massachusetts, United States

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SITE-13, La Jolla, California, United States

and more 8 locations

Safety and Efficacy Study of a BTK Inhibitor in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Phase 2
Completed
Conditions
Diffuse Large Cell B-lymphoma
Interventions
First Posted Date
2011-03-30
Last Posted Date
2017-03-31
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
78
Registration Number
NCT01325701
Locations
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UCLA Medical Center, Los Angeles, California, United States

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The Ohio Sate university, Columbus, Ohio, United States

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Univerity of Washington, Seattle, Washington, United States

and more 12 locations

Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL)

Phase 1
Completed
Conditions
Small Lymphocytic Lymphoma
B-cell Chronic Lymphocytic Leukemia
Interventions
First Posted Date
2011-02-09
Last Posted Date
2014-07-24
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
33
Registration Number
NCT01292135
Locations
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Weill Medical College of Cornell University, New York, New York, United States

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MD Anderson, Houston, Texas, United States

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Dana Farber Cancer Center, Boston, Massachusetts, United States

and more 3 locations

Safety and Efficacy of PCI-32765 in Participants With Relapsed/Refractory Mantle Cell Lymphoma (MCL)

Phase 2
Completed
Conditions
Mantle Cell Lymphoma
Interventions
First Posted Date
2010-11-08
Last Posted Date
2015-08-28
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
115
Registration Number
NCT01236391
Locations
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New York Presbyterian Hospital/Cornell Medical Center, New York, New York, United States

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Cll Research and Treatment Program, New Hyde Park, New York, United States

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Stanford University School of Medicine, Stanford, California, United States

and more 15 locations

Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLL

Phase 1
Completed
Conditions
B-cell Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Prolymphocyctic Leukemia
Richter's Transformation
Interventions
First Posted Date
2010-10-08
Last Posted Date
2015-06-25
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
71
Registration Number
NCT01217749
Locations
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The Ohio State University, Columbus, Ohio, United States

A Safety and Tolerability Study of PCI-24781 in Subjects With Cancer

Phase 1
Completed
Conditions
Lymphoma
Non-Hodgkin's Lymphoma
Hodgkin Disease
Multiple Myeloma
Leukemia
Lymphocytic
Interventions
First Posted Date
2010-06-23
Last Posted Date
2013-06-19
Lead Sponsor
Pharmacyclics LLC.
Target Recruit Count
7
Registration Number
NCT01149668
Locations
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Northwestern Univ. Med School, Chicago, Illinois, United States

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Nebraska Methodist Hospital, Omaha, Nebraska, United States

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Univ. of Nebraska Medical Center, Omaha, Nebraska, United States

and more 2 locations
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