DeepMed Research

University of Oxford

🇬🇧United Kingdom

Country: 🇬🇧United Kingdom

Ownership: Private

Established: 1096-01-01

Employees: 10K

Market Cap: -

Website: http://www.ox.ac.uk

Clinical Trials

The Effect of D-cycloserine on Emotional Processing

Not Applicable

Completed

Conditions: Healthy Volunteer
Cycloserine

Interventions: Drug: Placebo
Drug: d-cycloserine

First Posted Date: 2019-05-23

Last Posted Date: 2019-05-23

Lead Sponsor: University of Oxford

Target Recruit Count: 40

Registration Number: NCT03961464

Locations: 🇬🇧
University of Oxford, Oxford, United Kingdom

Noradrenaline, Acetylcholine and Dynamic Learning in Healthy Humans

Not Applicable

Completed

Conditions: Healthy

Interventions: Drug: Placebo oral tablet
Drug: Rivastigmine
Drug: Reboxetine

First Posted Date: 2019-05-21

Last Posted Date: 2020-06-16

Lead Sponsor: University of Oxford

Target Recruit Count: 107

Registration Number: NCT03957174

Locations: 🇬🇧
Dept of Psychiatry, University of Oxford, Oxford, Oxfordshire, United Kingdom

Paired Acute Invasive/Non-invasive Stimulation Trial

Not Applicable

Completed

Conditions: Chronic Pain

Interventions: Device: Transcranial direct current stimulation

First Posted Date: 2019-05-17

Last Posted Date: 2020-04-06

Lead Sponsor: University of Oxford

Target Recruit Count: 16

Registration Number: NCT03954093

Locations: 🇬🇧
John Radcliffe Hospital, Oxford, Oxfordshire, United Kingdom

A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adults

Phase 2

Terminated

Conditions: Malaria,Falciparum

Interventions: Biological: ChAd63/MVA ME-TRAP
Biological: R21/Matrix-M
Biological: intradermal injection (ID) or direct venous injection (DVI) of PfSPZ Challenge

First Posted Date: 2019-05-13

Last Posted Date: 2025-02-20

Lead Sponsor: University of Oxford

Target Recruit Count: 80

Registration Number: NCT03947190

Locations: 🇰🇪
KEMRI/Wellcome Trust Programme, Centre for Geographic Medicine Research - Coast, Kilifi, Kenya

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia)

Phase 3

Completed

Conditions: Plasmodium Falciparum Malaria (Uncomplicated)

Interventions: Drug: Artemether-lumefantrine+placebo
Drug: Artesunate-mefloquine+placebo
Drug: Artemether-lumefantrine+amodiaquine
Drug: Artesunate-mefloquine+piperaquine

First Posted Date: 2019-05-06

Last Posted Date: 2024-03-20

Lead Sponsor: University of Oxford

Target Recruit Count: 103

Registration Number: NCT03939104

Locations: 🇧🇩
Ramu Upazilla Health Complex, Cox's Bāzār, Chittagong, Bangladesh
🇰🇭
Kravanh Referral Hospital, Phnum Kravanh, Pursat, Cambodia
🇰🇭
Siem Pang Health Center, Siem Pang, Stung Treng, Cambodia

A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.

Phase 3

Recruiting

Conditions: Plasmodium Falciparum Malaria (Uncomplicated)

Interventions: Drug: Artemether-lumefantrine + placebo (AL+PBO)
Drug: Artemether-lumefantrine+ Amodiaquine (AL+AQ)
Drug: Artesunate-mefloquine+placebo (AS-MQ+PBO)
Drug: Artesunate-mefloquine+piperaquine (AS-MQ+PPQ)

First Posted Date: 2019-04-23

Last Posted Date: 2024-03-27

Lead Sponsor: University of Oxford

Target Recruit Count: 3240

Registration Number: NCT03923725

Locations: 🇨🇩
Kinshasa School of Public Health, Kinshasa, Congo, The Democratic Republic of the
🇳🇪
Epicentre Niger, Niamey, Niger
🇷🇼
College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda

and more 5 locations

Quality of Life in Pancreas Transplantation

Conditions: Diabetes Mellitus
Quality of Life

Interventions: Procedure: Solid Organ Pancreas Transplantation with or without Kidney Transplantation

First Posted Date: 2019-04-19

Last Posted Date: 2021-09-29

Lead Sponsor: University of Oxford

Target Recruit Count: 110

Registration Number: NCT03921593

Locations: 🇬🇧
Oxford University Hospital NHS Foundation Trust, Oxford, Oxfordshire, United Kingdom

Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer

Phase 1

Completed

Conditions: Locally Advanced Rectal Cancer

Interventions: Biological: Enadenotucirev
Drug: Capecitabine
Radiation: Radiotherapy

First Posted Date: 2019-04-16

Last Posted Date: 2025-02-06

Lead Sponsor: University of Oxford

Target Recruit Count: 12

Registration Number: NCT03916510

Locations: 🇬🇧
Velindre Cancer Centre, Cardiff, United Kingdom
🇬🇧
Royal Marsden NHS Foundation Trust, London Borough of Sutton, United Kingdom
🇬🇧
Beatson West Of Scotland Cancer Centre, Glasgow, United Kingdom

and more 1 locations

Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK Adults

Phase 1

Active, not recruiting

Conditions: Tuberculosis

Interventions: Biological: BCG Danish
Other: Saline placebo

First Posted Date: 2019-04-11

Last Posted Date: 2024-01-03

Lead Sponsor: University of Oxford

Target Recruit Count: 94

Registration Number: NCT03912207

Locations: 🇬🇧
Oxford University Hospitals- John Warin Ward, University of Oxford, Oxford, Oxfordshire, United Kingdom
🇬🇧
Centre for Clinical Vaccinology and Tropical Medicine (CCVTM), Churchill Hospital, Oxford, Oxfordshire, United Kingdom

VAC063C: A Study to Assess Repeat Blood-stage P. Falciparum Infection

Not Applicable

Completed

Conditions: Malaria

Interventions: Biological: Blood-stage controlled human P. falciparum malaria infection

First Posted Date: 2019-04-08

Last Posted Date: 2019-04-08

Lead Sponsor: University of Oxford

Target Recruit Count: 11

Registration Number: NCT03906474

Locations: 🇬🇧
CCVTM, University of Oxford, Churchill Hospital, Oxford, United Kingdom

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