MedPath

Amodiaquine

Generic Name
Amodiaquine
Drug Type
Small Molecule
Chemical Formula
C20H22ClN3O
CAS Number
86-42-0
Unique Ingredient Identifier
220236ED28
Background

A 4-aminoquinoquinoline compound with anti-inflammatory properties.

Indication

For treatment of acute malarial attacks in non-immune subjects.

Clinical Trials
Related News

Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique

Phase 4
Not yet recruiting
Conditions
Malaria,Falciparum
Chemoprevention
Interventions
First Posted Date
2024-03-29
Last Posted Date
2024-03-29
Lead Sponsor
Malaria Consortium
Target Recruit Count
1000
Registration Number
NCT06337253

Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control

Not Applicable
Not yet recruiting
Conditions
Malaria
Soil Transmitted Helminths
Schistosomiasis
Seasonal Malaria Chemoprevention
Mass Drug Administration With Anthelminthic Drugs
Interventions
First Posted Date
2023-12-26
Last Posted Date
2024-03-20
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
1200
Registration Number
NCT06182176

Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial

First Posted Date
2023-03-13
Last Posted Date
2024-12-11
Lead Sponsor
Muhimbili University of Health and Allied Sciences
Target Recruit Count
384
Registration Number
NCT05764746
Locations
🇹🇿

Kibindu, Bagamoyo, Dar esSalaam, Tanzania

🇹🇿

Yombo Dispensary, Bagamoyo, Yombo, Tanzania

Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali

Phase 2
Completed
Conditions
Malaria,Falciparum
Interventions
Drug: Artesunate-amodiaquine combination
First Posted Date
2022-09-22
Last Posted Date
2024-09-30
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
100
Registration Number
NCT05550909
Locations
🇲🇱

Malaria Research and Training Centre, Bamako, Mali

Chemoprevention Efficacy Study in Burkina Faso

Phase 4
Active, not recruiting
Conditions
Malaria
Interventions
First Posted Date
2022-07-28
Last Posted Date
2023-11-01
Lead Sponsor
Malaria Consortium
Target Recruit Count
800
Registration Number
NCT05478954
Locations
🇧🇫

Unité de Recherche Clinique de Nanoro, Nanoro, Burkina Faso

Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan

Phase 3
Active, not recruiting
Conditions
Malaria
Interventions
First Posted Date
2022-07-25
Last Posted Date
2024-03-25
Lead Sponsor
Malaria Consortium
Target Recruit Count
3575
Registration Number
NCT05471544
Locations
🇸🇸

Aweil South, Aweil, Northern Bahr El Gazal, South Sudan

Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children

Not Applicable
Conditions
Seasonal Malaria Chemoprevention
Mass Drug Administration With Anthelminthic Drugs
Soil Transmitted Helminths
Schistosomiasis
Malaria
Integrated Control
Interventions
First Posted Date
2022-04-29
Last Posted Date
2022-07-14
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
600
Registration Number
NCT05354258
Locations
🇸🇳

Saraya Health Centre, Saraya, Kedougou, Senegal

Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali

First Posted Date
2021-10-18
Last Posted Date
2022-01-18
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
80
Registration Number
NCT05081089
Locations
🇲🇱

Malaria Research and Training Centre, Bamako, Mali

Boosting the Impact of SMC Through Simultaneous Screening and Treatment of Roommates

Phase 4
Completed
Conditions
Malaria
Malaria Prophylaxis
Mass Testing and Treatment
Interventions
Diagnostic Test: Standard HRP2-RDT
First Posted Date
2021-03-25
Last Posted Date
2025-01-22
Lead Sponsor
Institut de Recherche en Sciences de la Sante, Burkina Faso
Target Recruit Count
526
Registration Number
NCT04816461
Locations
🇧🇫

Institut de Recherche en Sciences de la Santé/ Clinical Research Unit of Nanoro, Nanoro, Boulkiemdé, Burkina Faso

Pharmacokinetic Study of Artemether-lumefantrine and Amodiaquine in Healthy Subjects

Phase 1
Recruiting
Conditions
Pharmacokinetic
Healthy
Drug Combination
Interventions
First Posted Date
2019-09-06
Last Posted Date
2024-03-08
Lead Sponsor
University of Oxford
Target Recruit Count
16
Registration Number
NCT04080895
Locations
🇹🇭

Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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