Praziquantel
- Generic Name
- Praziquantel
- Brand Names
- Biltricide
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N2O2
- CAS Number
- 55268-74-1
- Unique Ingredient Identifier
- 6490C9U457
- Background
An anthelmintic used in most schistosome and many cestode infestations.
- Indication
For the treatment of infections due to all species of schistosoma.
- Associated Conditions
- Cestode infections, Cysticercosis, Liver fluke infection, Trematode infections, Schistosoma infection
Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children
- Conditions
- Seasonal Malaria ChemopreventionMass Drug Administration With Anthelminthic DrugsSoil Transmitted HelminthsSchistosomiasisMalariaIntegrated Control
- Interventions
- First Posted Date
- 2022-04-29
- Last Posted Date
- 2022-07-14
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 600
- Registration Number
- NCT05354258
- Locations
- 🇸🇳
Saraya Health Centre, Saraya, Kedougou, Senegal
Clinical Evaluation of Ujiplus® Against Schistosoma Mansoni
- Conditions
- Schistosoma Mansoni
- Interventions
- Dietary Supplement: Ujiplus®
- First Posted Date
- 2020-12-22
- Last Posted Date
- 2022-07-12
- Lead Sponsor
- Kenya Medical Research Institute
- Target Recruit Count
- 400
- Registration Number
- NCT04679831
- Locations
- 🇰🇪
Mbita, Mbita, Kenya
Monitoring Schistosome Hybrids Under Under Praziquantel Pressure
- Conditions
- Schistosomiasis
- First Posted Date
- 2020-11-19
- Last Posted Date
- 2020-11-19
- Lead Sponsor
- Institut de Recherche pour le Developpement
- Target Recruit Count
- 250
- Registration Number
- NCT04635553
- Locations
- 🇸🇳
Bruno SENGHOR, Dakar, Senegal
Bioequivalence Study of Coated Cesol Tablet Formulation Versus Biltricide
- First Posted Date
- 2020-03-18
- Last Posted Date
- 2021-08-13
- Lead Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 36
- Registration Number
- NCT04314037
- Locations
- 🇩🇪
Nuvisan GmbH, Neu-Ulm, Germany
Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study
- Conditions
- Schistosomiasis
- Interventions
- First Posted Date
- 2019-10-03
- Last Posted Date
- 2020-05-18
- Lead Sponsor
- Vendsyssel Hospital
- Target Recruit Count
- 116
- Registration Number
- NCT04115072
- Locations
- 🇲🇬
K'Olo Vanona, Ambanja, Diana, Madagascar
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children
- Conditions
- Schistosoma HaematobiumSchistosoma Mansoni
- Interventions
- First Posted Date
- 2019-03-28
- Last Posted Date
- 2021-04-05
- Lead Sponsor
- Institute of Tropical Medicine, Belgium
- Target Recruit Count
- 726
- Registration Number
- NCT03893097
- Locations
- 🇸🇳
Institut de Recherche en Santé, de Surveillance Épidémiologique et de Formation (IRESSEF), Dakar, Senegal
L-PZQ ODT in Schistosoma Infected Children
- Conditions
- Schistosomiasis
- Interventions
- First Posted Date
- 2019-02-19
- Last Posted Date
- 2024-03-21
- Lead Sponsor
- Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 288
- Registration Number
- NCT03845140
- Locations
- 🇰🇪
Kemri Kisumu, Kisumu, Kenya
🇨🇮Universitè de Cocody, Abidjan, Côte D'Ivoire
Schistosomiasis Diagnosis Using a CAA Antigen Test
- Conditions
- Schistosomiasis HematobiumDiagnosticDrug ReactionPregnancy
- Interventions
- First Posted Date
- 2018-12-19
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Centre de Recherche Médicale de Lambaréné
- Target Recruit Count
- 100
- Registration Number
- NCT03779347
- Locations
- 🇬🇦
Centre de Recherches Médicales de Lambaréné, Lambaréné, Moyen Ogooué, Gabon
🇬🇦Centre de Recherches Medicales de Lambaréné, Lambaréné, Gabon
Praziquantel in Children Under Age 4
- Conditions
- SchistosomiasisSchistosomiasis MansoniSchistosoma Japonicum Infection
- Interventions
- First Posted Date
- 2018-08-21
- Last Posted Date
- 2022-05-20
- Lead Sponsor
- Rhode Island Hospital
- Target Recruit Count
- 600
- Registration Number
- NCT03640377
- Locations
- 🇬🇧
London School of Tropical Hygiene and Medicine, London, United Kingdom
🇺🇬Medical Research Council, Entebbe, Uganda
Praziquantel Bioequivalence Study
- First Posted Date
- 2018-02-19
- Last Posted Date
- 2019-09-18
- Lead Sponsor
- Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 60
- Registration Number
- NCT03437447
- Locations
- 🇲🇽
Clínica de Enfermedades Crónicas y de Procedimientos Especiales, Sociedad Civil (SC), México, Mexico
Drug Development Updates
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