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Novartis AG

Novartis AG logo
🇨🇭Switzerland
Ownership
Public, Private
Established
1996-01-01
Employees
76K
Market Cap
$242.6B
Website
https://www.novartis.com/our-science/novartis-institutes-biomedical-research
Introduction

Novartis develops and manufactures innovative drugs. The firm's key areas of drug development include oncology, rare diseases, neuroscience, immunology, respiratory, cardio-metabolic, and established medicines. The company sells its products globally, with the United States comprising close to one third of total revenue.

Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)

Phase 3
Completed
Conditions
Renal Insufficiency
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2008-10-09
Last Posted Date
2020-12-17
Lead Sponsor
Novartis
Target Recruit Count
75
Registration Number
NCT00770081
Locations
🇺🇸

Atlanta Diabetes Associates, Atlanta, Georgia, United States

🇺🇸

Emory Clinic, Atlanta, Georgia, United States

🇺🇸

Renal Endocrine Associates, P. C., Pittsburgh, Pennsylvania, United States

and more 81 locations

Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate Hypertension

Phase 4
Completed
Conditions
Essential Hypertension ( Mild to Moderate)
Interventions
First Posted Date
2008-10-03
Last Posted Date
2020-08-06
Lead Sponsor
Novartis
Target Recruit Count
256
Registration Number
NCT00765947
Locations
🇸🇰

Investigative Site, Bratislava, Slovakia

Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe Hypertension

Phase 3
Completed
Conditions
Hypertension
Interventions
First Posted Date
2008-10-03
Last Posted Date
2011-05-09
Lead Sponsor
Novartis
Target Recruit Count
1191
Registration Number
NCT00765674
Locations
🇹🇷

Investigative Site, Ankara, Turkey

Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency (28 Week Extension)

Phase 3
Completed
Conditions
Diabetes Mellitus, Type 2
Renal Insufficiency
Interventions
Drug: Placebo
First Posted Date
2008-10-03
Last Posted Date
2020-12-17
Lead Sponsor
Novartis
Target Recruit Count
349
Registration Number
NCT00765830
Locations
🇪🇸

Hospital de la Ribera, Alzira, Spain

🇪🇸

Hospital San Pedro de Alcantara, Caceres, Spain

🇪🇸

Clinica Mediterranea de Neurociencias, Alicante, Spain

and more 86 locations

Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population

Phase 4
Completed
Conditions
Hypertension
Interventions
First Posted Date
2008-09-26
Last Posted Date
2011-04-04
Lead Sponsor
Novartis
Target Recruit Count
451
Registration Number
NCT00760266
Locations
🇺🇸

Sites in USA, East Hanover, New Jersey, United States

Safety and Efficacy of Albumin Interferon Administered Every 4 Weeks in Genotype 2/3 Hepatitis C Patients

Phase 2
Completed
Conditions
Chronic Hepatitis C
Interventions
Drug: alb-interferon alfa 2b
Drug: peg-interferon
First Posted Date
2008-09-25
Last Posted Date
2016-11-16
Lead Sponsor
Novartis
Target Recruit Count
525
Registration Number
NCT00759200
Locations
🇹🇭

Novartis Investigative site, Chaingmai, Thailand

🇬🇧

Novartis Investigative Site, Glasgow, United Kingdom

Single Dose Study of the Effect of Formoterol Fumarate in Combination With Mometasone Furoate Inhaled Via a Pressurized Metered Dose Inhaler (pMDI) in Children Aged 5-11 Years Old With Persistent Asthma

First Posted Date
2008-09-04
Last Posted Date
2011-06-07
Lead Sponsor
Novartis
Target Recruit Count
32
Registration Number
NCT00746330
Locations
🇵🇪

Novartis Investigative Site, Lima, Peru

Study to Evaluate the Efficacy, Safety, Tolerability and Immunogenicity of 100µg NIC002 Vaccine in Cigarette Smokers Who Are Motivated to Quit Smoking.

Phase 2
Completed
Conditions
Smokers
Interventions
Biological: Placebo
Biological: NIC002
First Posted Date
2008-08-15
Last Posted Date
2017-03-21
Lead Sponsor
Novartis
Target Recruit Count
200
Registration Number
NCT00736047
Locations
🇩🇪

Novartis Investigator Site, Neuss, Germany

🇩🇪

Novartis Investigative Site, Mainz, Germany

Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients.

Phase 2
Completed
Conditions
Alzheimer Disease
Interventions
Biological: CAD106
Biological: Placebo
First Posted Date
2008-08-13
Last Posted Date
2020-02-11
Lead Sponsor
Novartis
Target Recruit Count
27
Registration Number
NCT00733863
Locations
🇫🇷

Centre Hospitalier Universitaire Pellegrin, Bordeaux, France

🇸🇪

Karolinska Universitetssjukhuset Huddinge, Stockholm, Sweden

🇬🇧

Moorgreen Hospital, Southampton, United Kingdom

and more 1 locations

Proof-of-concept for the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism

Phase 2
Completed
Conditions
Primary Hyperaldosteronism
Interventions
First Posted Date
2008-08-12
Last Posted Date
2009-08-26
Lead Sponsor
Novartis
Target Recruit Count
12
Registration Number
NCT00732771
Locations
🇫🇷

Novartis Investigator Site, France, France

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