Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Public
Established
1989-01-01
Employees
5.4K
Market Cap
$123.9B
Website
http://www.vrtx.com

A Microneurography Study of NaV1.8 Inhibition in Healthy Adults

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-05-20
Last Posted Date
2024-08-14
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
40
Registration Number
NCT06420765
Locations
πŸ‡¬πŸ‡§

MAC Clinical Research, Manchester, United Kingdom

A Phase 1 Dose Escalation Study of Intravenous VX-993 in Healthy Adults

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-05-01
Last Posted Date
2024-05-30
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
110
Registration Number
NCT06394167
Locations
πŸ‡ΊπŸ‡Έ

ICON Lenexa, Lenexa, Kansas, United States

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

First Posted Date
2024-04-30
Last Posted Date
2024-08-01
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
42
Registration Number
NCT06392659
Locations
πŸ‡¬πŸ‡§

MAC Clinical Research, Manchester, United Kingdom

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

First Posted Date
2024-04-03
Last Posted Date
2024-05-17
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
95
Registration Number
NCT06345755
Locations
πŸ‡ΊπŸ‡Έ

ICON Lenexa, Lenexa, Kansas, United States

A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-03-28
Last Posted Date
2024-07-19
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
48
Registration Number
NCT06336096
Locations
πŸ‡ΊπŸ‡Έ

Celerion - Tempe, Tempe, Arizona, United States

A Study to Evaluate the Relative Bioavailability and Food Effect of a VX-118 Tablet Formulation

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-03-15
Last Posted Date
2024-06-03
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
15
Registration Number
NCT06312787
Locations
πŸ‡ΊπŸ‡Έ

Celerion - Lincoln, Lincoln, Nebraska, United States

A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-03-08
Last Posted Date
2024-05-16
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
10
Registration Number
NCT06299696
Locations
πŸ‡ΊπŸ‡Έ

Site 001, Woburn, Massachusetts, United States

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-03-08
Last Posted Date
2024-06-24
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
34
Registration Number
NCT06299709
Locations
πŸ‡ΊπŸ‡Έ

Celerion, Inc., Tempe, Arizona, United States

A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993

Phase 1
Completed
Conditions
Interventions
First Posted Date
2024-01-26
Last Posted Date
2024-07-12
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
39
Registration Number
NCT06226454
Locations
πŸ‡ΊπŸ‡Έ

ICON Salt Lake City, Salt Lake City, Utah, United States

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-12-29
Last Posted Date
2024-12-12
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
36
Registration Number
NCT06185764
Locations
πŸ‡¨πŸ‡¦

McGill University, Montreal, Canada

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Altasciences Montreal, Mont-Royal, Canada

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Neuroscience Clinical Trials Unit, Alfred Brain, Melbourne, Australia

and more 8 locations
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