Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated logo
🇺🇸United States
Ownership
Public
Established
1989-01-01
Employees
5.4K
Market Cap
$123.9B
Website
http://www.vrtx.com

Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects

First Posted Date
2009-08-27
Last Posted Date
2010-01-05
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
24
Registration Number
NCT00966602

Drug-Drug Interaction Study of VCH-222 and Telaprevir in Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-08-13
Last Posted Date
2010-01-07
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
30
Registration Number
NCT00958152

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2009-08-06
Last Posted Date
2015-09-11
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
140
Registration Number
NCT00953706
Locations
🇺🇸

Maine Medical Center, Portland, Maine, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

University of Miami Miller School of Medicine, Miami, Florida, United States

and more 31 locations

A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors

Not Applicable
Withdrawn
Conditions
First Posted Date
2009-06-18
Last Posted Date
2014-01-10
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Registration Number
NCT00923728
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Virology Follow up Study in Subjects Previously Treated With Telaprevir

Completed
Conditions
Interventions
First Posted Date
2009-06-09
Last Posted Date
2014-02-27
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
408
Registration Number
NCT00916474
Locations
🇺🇸

Maryland, Baltimore, Maryland, United States

🇺🇸

South Carolina, Columbia, South Carolina, United States

🇺🇸

Florida, Miami, Florida, United States

and more 17 locations

Pharmacokinetics of Multiple Ascending Doses of VCH-222 in Subjects With Chronic Hepatitis C Infection

First Posted Date
2009-06-03
Last Posted Date
2014-03-10
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
49
Registration Number
NCT00911963
Locations
🇺🇸

Alamo Medical Research, San Antonio, Texas, United States

🇨🇦

Downtown ID Clinic/University of British Columbia, Vancouver, British Columbia, Canada

🇨🇦

Ottawa Hospital, Ottawa, Ontario, Canada

and more 7 locations

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-05-28
Last Posted Date
2012-08-21
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
52
Registration Number
NCT00909727
Locations
🇺🇸

The Children's Mercy Hospital, Kansas City, Missouri, United States

🇺🇸

Children's Memorial Hospital, Chicago, Illinois, United States

🇺🇸

Riley Hospital for Children, Indianapolis, Indiana, United States

and more 26 locations

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-05-28
Last Posted Date
2013-01-18
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
167
Registration Number
NCT00909532
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇦🇺

Royal Children's Hospital Brisbane, Herston, Queensland, Australia

and more 62 locations

Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-03-19
Last Posted Date
2015-08-28
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
93
Registration Number
NCT00865904

Single and Multiple Dose Escalation Study of VX-509 in Healthy Subjects

Phase 1
Completed
Conditions
First Posted Date
2008-11-11
Last Posted Date
2009-02-19
Lead Sponsor
Vertex Pharmaceuticals Incorporated
Target Recruit Count
72
Registration Number
NCT00789126
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