Vertex Pharmaceuticals Incorporated
- Country
- 🇺🇸United States
- Ownership
- Public
- Established
- 1989-01-01
- Employees
- 5.4K
- Market Cap
- $123.9B
- Website
- http://www.vrtx.com
Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)
- First Posted Date
- 2023-12-19
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 218
- Registration Number
- NCT06176196
- Locations
- 🇺🇸
Trovare Clinical Research, Bakersfield, California, United States
🇺🇸Velocity Clinical Research - Banning, Banning, California, United States
🇺🇸ARSN-Brain and Spine Institute, Port Orange, Florida, United States
A Phase 1, First-in-human Study of VX-828
- Conditions
- Interventions
- First Posted Date
- 2023-12-04
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 159
- Registration Number
- NCT06154447
- Locations
- 🇺🇸
Altasciences Clinical Kansas, Overland Park, Kansas, United States
A Study Evaluating the Relative Bioavailability and Food Effect of a Tablet Formulation of VX-147
- First Posted Date
- 2023-07-21
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 21
- Registration Number
- NCT05955872
- Locations
- 🇺🇸
ICON Salt Lake City, Salt Lake City, Utah, United States
Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/βC Genotype
- First Posted Date
- 2023-07-18
- Last Posted Date
- 2024-02-29
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 12
- Registration Number
- NCT05951205
Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age
- First Posted Date
- 2023-05-31
- Last Posted Date
- 2024-08-15
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 64
- Registration Number
- NCT05882357
- Locations
- 🇳🇱
Erasmus Medical Center / Sophia Children's Hospital, Rotterdam, Netherlands
🇨🇦The Hospital for Sick Children, Toronto, Canada
🇦🇺Telethon Kids Institute, Nedlands, Australia
A Phase 1 Dose Escalation Study of VX-973 in Healthy Adults
- First Posted Date
- 2023-05-19
- Last Posted Date
- 2024-05-06
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 30
- Registration Number
- NCT05866055
- Locations
- 🇬🇧
PAREXEL International, Harrow, United Kingdom
An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2023-05-19
- Last Posted Date
- 2023-07-14
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 56
- Registration Number
- NCT05867147
- Locations
- 🇺🇸
Celerion - Tempe, Tempe, Arizona, United States
A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment
- First Posted Date
- 2023-05-18
- Last Posted Date
- 2024-07-12
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 16
- Registration Number
- NCT05865171
- Locations
- 🇺🇸
GCP Research, Ocala, Florida, United States
🇺🇸Genesis Clinical Research, Tampa, Florida, United States
A Study to Evaluate the Effect of Food on the Pharmacokinetics of VX-548
- First Posted Date
- 2023-05-09
- Last Posted Date
- 2024-03-20
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 73
- Registration Number
- NCT05851157
- Locations
- 🇺🇸
ICON Salt Lake City, Salt Lake City, Utah, United States
Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older
- First Posted Date
- 2023-05-06
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 180
- Registration Number
- NCT05844449
- Locations
- 🇨🇭
Inselspital - Universitaetsspital Bern, Bern, Switzerland
🇸🇪Sahlgrenska Universitetssjukhuset, Göteborg, Sweden
🇩🇪Charite Paediatric Pulmonology Department, Berlin, Germany