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Biogen

Biogen logo
🇺🇸United States
Ownership
Private
Established
1978-01-01
Employees
7.5K
Market Cap
$29.6B
Website
https://www.biogen.com
Introduction

Biogen, Inc. is a biopharmaceutical company, which engages in discovering, developing, and delivering therapies for neurological and neurodegenerative diseases. Its products include TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI and FAMPYRA for the treatment of MS, SPINRAZA for the treatment of SMA, ADUHELM for the treatment of Alzheimer's disease, and FUMADERM for the treatment of severe plaque psoriasis. The company was founded by Charles Weissmann, Heinz Schaller, Kenneth Murray, Walter Gilbert, and Phillip Allen Sharp in 1978 and is headquartered in Cambridge, MA.

Natalizumab (Tysabri) Re-Initiation of Dosing

Phase 3
Terminated
Conditions
Relapsing-Remitting Multiple Sclerosis
Interventions
First Posted Date
2006-02-28
Last Posted Date
2016-07-15
Lead Sponsor
Biogen
Target Recruit Count
1094
Registration Number
NCT00297232
Locations
🇬🇧

Research Site, Stoke on Trent, United Kingdom

Dose-Escalating Study of BG9924 in Combination With Methotrexate in Active Rheumatoid Arthritis

Phase 2
Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2006-02-16
Last Posted Date
2007-12-31
Lead Sponsor
Biogen
Target Recruit Count
50
Registration Number
NCT00292422
Locations
🇺🇸

Fiechtner Research Inc., Lansing, Michigan, United States

🇺🇸

Arthritis Consultants Inc., St. Louis, Missouri, United States

🇵🇱

Klinika Chorob Tkanki Lacznej-Instytut Reumatologiczny, Warsawa, Poland

and more 7 locations

A Serologic Study to Correlate Beta-IFN NAb Titers to Beta-IFN Induced Biomarker Response in Patients With Multiple Sclerosis

Completed
Conditions
Multiple Sclerosis
First Posted Date
2006-02-09
Last Posted Date
2007-12-24
Lead Sponsor
Biogen
Target Recruit Count
300
Registration Number
NCT00288990
Locations
🇺🇸

The Baptist Hospital of East Tennessee, Knoxville, Tennessee, United States

🇺🇸

Neurology Center of Fairfax, Ltd., Fairfax, Virginia, United States

🇺🇸

The Multiple Sclerosis Center at the Ohio State University, Columbus, Ohio, United States

and more 25 locations

Open Label Natalizumab Safety Extension Study for Subjects With Crohn's Disease

Phase 4
Completed
Conditions
Crohn's Disease
First Posted Date
2006-01-24
Last Posted Date
2016-06-16
Lead Sponsor
Biogen
Target Recruit Count
2000
Registration Number
NCT00280956
Locations
🇺🇸

Performed only at CD251, CD301, CD303, CD306, and CD307 sites globally. No general public enrollment. The study is managed from the office of Elan Pharmaceuticals, Inc. in, San Diego, California, United States

Open-Label Natalizumab Safety Extension Study

Phase 3
Completed
Conditions
Multiple Sclerosis
Interventions
First Posted Date
2006-01-13
Last Posted Date
2009-06-22
Lead Sponsor
Biogen
Target Recruit Count
1615
Registration Number
NCT00276172
Locations
🇺🇸

Performed at only C-1801, C-1802, and C-1803 sites globally. No general public enrollment. Biogen Idec is located in, Cambridge, Massachusetts, United States

Safety and Tolerability of Repeat Courses of IM Alefacept

Phase 3
Completed
Conditions
Chronic Plaque Psoriasis
First Posted Date
2005-10-06
Last Posted Date
2023-08-23
Lead Sponsor
Biogen
Target Recruit Count
400
Registration Number
NCT00233662
Locations
🇨🇦

Dermatrials Research, Hamilton, Ontario, Canada

🇺🇸

Loyola University Medical Center, Maywood, Illinois, United States

🇫🇷

Hopital L'Archet II, Nice, France

and more 43 locations

Pregnancy Exposure Registry for Avonex (Interferon Beta-1a)

Completed
Conditions
Prenatal Exposure Delayed Effects
Multiple Sclerosis
Pregnancy
Interventions
Drug: BG9418 (interferon beta-1a)
First Posted Date
2005-09-15
Last Posted Date
2014-06-09
Lead Sponsor
Biogen
Target Recruit Count
329
Registration Number
NCT00168714
Locations
🇺🇸

Kendle, Wilmington, North Carolina, United States

Avonex (Interferon-beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-remitting MS

Phase 4
Completed
Conditions
Relapsing-remitting Multiple Sclerosis
Interventions
First Posted Date
2005-09-15
Last Posted Date
2013-09-16
Lead Sponsor
Biogen
Target Recruit Count
345
Registration Number
NCT00168766
Locations
🇨🇭

Kantonspital, St. Gallen, Switzerland

🇧🇪

CUB Hôpital Erasme, Bruxelles, Belgium

🇳🇱

Stichting MS Centrum, Nijemegen, Netherlands

and more 6 locations

Efficacy and Safety of BG00012 in MS

Phase 2
Completed
Conditions
Multiple Sclerosis
First Posted Date
2005-09-15
Last Posted Date
2023-08-28
Lead Sponsor
Biogen
Target Recruit Count
260
Registration Number
NCT00168701
Locations
🇸🇪

MS Centrum, Molndal, Sweden

🇨🇿

Faculty Hospital, Hradec Kralove, Czechia

🇨🇿

General Teaching Hospital, Prague, Czechia

and more 28 locations

Treatment of Relapsed Low-Grade or Follicular Lymphoma With Rituximab (Also Known as Rituxan, IDEC-C2B8, IDEC-102)

Phase 3
Completed
Conditions
Low-Grade or Follicular B-Cell Non-Hodgkin's Lymphoma
First Posted Date
2005-09-15
Last Posted Date
2005-09-15
Lead Sponsor
Biogen
Target Recruit Count
150
Registration Number
NCT00168740
Locations
🇺🇸

Hoag Hospital, Newport Beach, California, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

🇺🇸

Robert H. Lurie Cancer Center, Northwestern University, Chicago, Illinois, United States

and more 28 locations
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