MAYO CLINIC

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary

Established: 1889-01-01

Employees: 10K

Market Cap: -

Website: http://www.mayoclinic.org

Clinical Trials

Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer

Conditions: Anatomic Stage III Breast Cancer AJCC V8
Locally Advanced Breast Carcinoma
Resectable Breast Carcinoma

Interventions: Procedure: Magnetic Resonance Imaging
Procedure: Mammogram
Procedure: Ultrasound
Procedure: Ultrasound-Guided Biopsy
Device: Twinkle marker

First Posted Date: 2022-09-21

Last Posted Date: 2025-03-03

Lead Sponsor: Mayo Clinic

Target Recruit Count: 10

Registration Number: NCT05547347

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

A Study of Paravertebral Block in Thoracic Outlet Syndrome

Phase 4

Conditions: Thoracic Outlet Syndrome

Interventions: Drug: Ropivacaine

First Posted Date: 2022-09-16

Last Posted Date: 2024-12-05

Lead Sponsor: Mayo Clinic

Target Recruit Count: 50

Registration Number: NCT05544721

Locations: 🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 CtHPV-DNA

Phase 2

Recruiting

Conditions: Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC V8

Interventions: Procedure: Biospecimen Collection
Procedure: Computed Tomography
Drug: Cisplatin
Procedure: Magnetic Resonance Imaging
Radiation: Diffusing Alpha-emitter Radiation Therapy
Procedure: Modified Barium Swallow Study
Procedure: Intensity-Modulated Proton Therapy
Drug: Docetaxel
Other: Observation
Radiation: Intensity-Modulated Radiation Therapy
Procedure: Positron Emission Tomography
Other: Quality-of-Life Assessment
Other: Questionnaire

First Posted Date: 2022-09-15

Last Posted Date: 2025-02-21

Lead Sponsor: Mayo Clinic

Target Recruit Count: 320

Registration Number: NCT05541016

Locations: 🇺🇸
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States
🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Effect of Acute Exercise on Exosome Associated Biomarkers

Completed

Conditions: Healthy

First Posted Date: 2022-09-15

Last Posted Date: 2025-04-09

Lead Sponsor: Mayo Clinic

Target Recruit Count: 12

Registration Number: NCT05541133

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function

Early Phase 1

Recruiting

Conditions: Healthy

Interventions: Drug: Indomethacin
Dietary Supplement: S. boulardii CNCM I-745
Drug: Placebo

First Posted Date: 2022-09-13

Last Posted Date: 2025-01-06

Lead Sponsor: Mayo Clinic

Target Recruit Count: 56

Registration Number: NCT05538247

Locations: 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

Not Applicable

Completed

Conditions: Stroke
Upper Extremity Weakness

Interventions: Device: Sequential Compression Device

First Posted Date: 2022-09-10

Last Posted Date: 2025-01-09

Lead Sponsor: Mayo Clinic

Target Recruit Count: 20

Registration Number: NCT05535257

Locations: 🇺🇸
C Joseph Yelvington, Saint Johns, Florida, United States

A Study of Physiologic Changes in a Telemetry Unit

Conditions: Acute Illness Requiring to Hospital Telemetry Admission

First Posted Date: 2022-09-09

Last Posted Date: 2025-04-01

Lead Sponsor: Mayo Clinic

Target Recruit Count: 500

Registration Number: NCT05534516

Locations: 🇺🇸
Mayo Clinic Florida, Jacksonville, Florida, United States

Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal

Recruiting

Conditions: Metastatic Malignant Solid Neoplasm
Hematopoietic and Lymphoid System Neoplasm

Interventions: Procedure: Biopsy Specimen
Procedure: Biospecimen Collection
Other: Medical Chart Review

First Posted Date: 2022-09-07

Last Posted Date: 2025-04-02

Lead Sponsor: Mayo Clinic

Target Recruit Count: 50

Registration Number: NCT05530759

Locations: 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

Not Applicable

Recruiting

Conditions: Stage I Soft Tissue Sarcoma of the Trunk and Extremities
Soft Tissue Sarcoma
Stage III Soft Tissue Sarcoma of the Trunk and Extremities
Stage II Soft Tissue Sarcoma of the Trunk and Extremities

Interventions: Procedure: Computed Tomography
Other: Educational Intervention
Procedure: Magnetic Resonance Imaging
Procedure: Physical Therapy
Other: Questionnaire Administration
Other: Telemedicine

First Posted Date: 2022-09-02

Last Posted Date: 2024-12-05

Lead Sponsor: Mayo Clinic

Target Recruit Count: 30

Registration Number: NCT05526417

Locations: 🇺🇸
Mayo Clinic in Arizona, Scottsdale, Arizona, United States

Prevention of Hepatic Encephalopathy With Mobile Application Based Lactulose Titration

Not Applicable

Completed

Conditions: Hepatic Encephalopathy

Interventions: Other: Dieta mobile application

First Posted Date: 2022-09-02

Last Posted Date: 2023-08-18

Lead Sponsor: Mayo Clinic

Target Recruit Count: 50

Registration Number: NCT05526404

Locations: 🇺🇸
Mayo Clinic Rochester, Rochester, Minnesota, United States

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