Effect of Acute Exercise on Exosome Associated Biomarkers

Mayo Clinic1 site in 1 country12 target enrollmentJune 21, 2022

ConditionsHealthy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Healthy
Sponsor: Mayo Clinic
Enrollment: 12
Locations: 1
Primary Endpoint: List of biomarkers
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This research study is being done to understand the underlying mechanism by which exercise affects the body on the cellular level, in an acute aerobic endurance setting. This may help to better understand the overall benefits of endurance exercise.

Registry

clinicaltrials.gov

Start Date

June 21, 2022

End Date

December 31, 2024

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Mayo Clinic

Responsible Party

Principal Investigator

K. Sreekumaran Nair

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

•Ages: 18 to 45 years

Exclusion Criteria

•BMI \>32 kg/m
•Cardiovascular, metabolic (type 2 diabetes, fasting plasma glucose at or above 110 mg/dL and untreated hypo- or hyperthyroidism) or renal disease.
•Orthopedic problems that would keep them from being able to perform an exercise. - --
•Medications that are known to affect mitochondrial function: Corticosteroids, opiates, benzodiazepines, tricyclic antidepressants, beta-blockers, sulfonylureas, insulin, anticoagulants, barbiturates, insulin sensitizers, fibrates (PPAR gamma agonist).
•Pregnancy.