NCT05541133已完成不适用
Effect of Acute Exercise on Exosome Associated Biomarkers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- List of biomarkers
研究概览
简要总结
This research study is being done to understand the underlying mechanism by which exercise affects the body on the cellular level, in an acute aerobic endurance setting. This may help to better understand the overall benefits of endurance exercise.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages: 18 to 45 years
排除标准
- •BMI >32 kg/m
- •Cardiovascular, metabolic (type 2 diabetes, fasting plasma glucose at or above 110 mg/dL and untreated hypo- or hyperthyroidism) or renal disease.
- •Orthopedic problems that would keep them from being able to perform an exercise. - --
- •Medications that are known to affect mitochondrial function: Corticosteroids, opiates, benzodiazepines, tricyclic antidepressants, beta-blockers, sulfonylureas, insulin, anticoagulants, barbiturates, insulin sensitizers, fibrates (PPAR gamma agonist).
- •Pregnancy.
结局指标
主要结局
List of biomarkers
时间窗: Baseline
Exosome proteomes and MiRNA from blood samples
次要结局
未报告次要终点
研究者
K. Sreekumaran Nair
Principal Investigator
Mayo Clinic
研究点 (1)
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