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NRG Oncology

NRG Oncology logo
🇺🇸United States
Ownership
Private
Established
2014-01-01
Employees
51
Market Cap
-
Website
http://www.nrgoncology.org

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Phase 2
Suspended
Conditions
Hard Palate Squamous Cell Carcinoma
Lip Squamous Cell Carcinoma
Stage I Lip and Oral Cavity Cancer AJCC v8
Tongue Squamous Cell Carcinoma
Lower Alveolar Ridge Squamous Cell Carcinoma
Retromolar Trigone Squamous Cell Carcinoma
Stage II Lip and Oral Cavity Cancer AJCC v8
Buccal Mucosa Squamous Cell Carcinoma
Floor of Mouth Squamous Cell Carcinoma
Gingival Squamous Cell Carcinoma
Interventions
Procedure: Chest Radiography
Procedure: Computed Tomography
Other: Fludeoxyglucose F-18
Procedure: Neck Dissection
Drug: Imaging Agent
Procedure: Planar Imaging
Procedure: Positron Emission Tomography
Other: Questionnaire Administration
Procedure: Sentinel Lymph Node Biopsy
Procedure: Single Photon Emission Computed Tomography
First Posted Date
2020-04-03
Last Posted Date
2025-05-09
Lead Sponsor
NRG Oncology
Target Recruit Count
686
Registration Number
NCT04333537
Locations
🇺🇸

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

🇺🇸

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

🇺🇸

Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States

and more 94 locations

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Not Applicable
Recruiting
Conditions
Ovarian Carcinoma
Interventions
Procedure: Bilateral Salpingectomy
Procedure: Bilateral Salpingectomy with Oophorectomy
Procedure: Biospecimen Collection
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Procedure: Transvaginal Ultrasound
Procedure: Ultrasound Imaging
First Posted Date
2020-01-31
Last Posted Date
2025-05-20
Lead Sponsor
NRG Oncology
Target Recruit Count
2262
Registration Number
NCT04251052
Locations
🇺🇸

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

🇺🇸

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States

🇺🇸

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

and more 506 locations

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Phase 3
Terminated
Conditions
Pleural Biphasic Mesothelioma
Pleural Epithelioid Mesothelioma
Stage I Pleural Malignant Mesothelioma AJCC v8
Stage IA Pleural Malignant Mesothelioma AJCC v8
Stage IB Pleural Malignant Mesothelioma AJCC v8
Stage II Pleural Malignant Mesothelioma AJCC v8
Stage IIIA Pleural Malignant Mesothelioma AJCC v8
Interventions
Procedure: Decortication
Radiation: Intensity-Modulated Radiation Therapy
Radiation: Pencil beam scanning proton therapy
Procedure: Pleurectomy
First Posted Date
2019-11-08
Last Posted Date
2025-02-19
Lead Sponsor
NRG Oncology
Target Recruit Count
16
Registration Number
NCT04158141
Locations
🇨🇦

The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec, Canada

🇺🇸

Moffitt Cancer Center - McKinley Campus, Tampa, Florida, United States

🇺🇸

Memorial Sloan Kettering Bergen, Montvale, New Jersey, United States

and more 24 locations

Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

Phase 3
Recruiting
Conditions
Prostate Adenocarcinoma
Stage I Prostate Cancer AJCC v8
Stage II Prostate Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Bone Scan
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Radiation: Radiation Therapy
First Posted Date
2019-10-22
Last Posted Date
2025-05-11
Lead Sponsor
NRG Oncology
Target Recruit Count
586
Registration Number
NCT04134260
Locations
🇺🇸

Cancer Center at Saint Joseph's, Phoenix, Arizona, United States

🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

🇺🇸

Kaiser Permanente-Anaheim, Anaheim, California, United States

and more 331 locations

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Phase 2
Withdrawn
Conditions
Anaplastic Astrocytoma
Glioblastoma
Oligodendroglioma
Supratentorial Glioblastoma
Interventions
Device: NovoTTF-100A Device
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Radiation: Radiation Therapy
Procedure: Therapeutic Conventional Surgery
Biological: Vocimagene Amiretrorepvec
First Posted Date
2019-09-26
Last Posted Date
2020-03-24
Lead Sponsor
NRG Oncology
Registration Number
NCT04105374

Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 3
Active, not recruiting
Conditions
Ovarian Low Grade Serous Adenocarcinoma
Primary Peritoneal Low Grade Serous Adenocarcinoma
Stage IV Primary Peritoneal Cancer AJCC v8
Low Grade Fallopian Tube Serous Adenocarcinoma
Stage II Fallopian Tube Cancer AJCC v8
Stage II Ovarian Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage IV Fallopian Tube Cancer AJCC v8
Stage II Primary Peritoneal Cancer AJCC v8
Stage III Fallopian Tube Cancer AJCC v8
Interventions
Procedure: Biopsy Procedure
Procedure: Biospecimen Collection
Procedure: Imaging Procedure
First Posted Date
2019-09-19
Last Posted Date
2025-05-20
Lead Sponsor
NRG Oncology
Target Recruit Count
450
Registration Number
NCT04095364
Locations
🇺🇸

Unity Hospital, Fridley, Minnesota, United States

🇺🇸

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

🇺🇸

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States

and more 907 locations

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

Phase 2
Active, not recruiting
Conditions
Colon Adenocarcinoma
Stage IIA Colon Cancer AJCC v8
Interventions
First Posted Date
2019-08-28
Last Posted Date
2025-05-07
Lead Sponsor
NRG Oncology
Target Recruit Count
635
Registration Number
NCT04068103
Locations
🇺🇸

Kaiser Permanente-Franklin, Denver, Colorado, United States

🇺🇸

Norwalk Hospital, Norwalk, Connecticut, United States

🇺🇸

Illinois CancerCare-Carthage, Carthage, Illinois, United States

and more 950 locations

Testing the Addition of a New Anti-Cancer Drug, Niraparib, to the Usual Treatment (Hormone and Radiation Therapy) for Prostate Cancer With a High Chance of Recurring

Phase 1
Active, not recruiting
Conditions
Prostate Adenocarcinoma
Stage IIC Prostate Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Stage IIIA Prostate Cancer AJCC v8
Stage IIIB Prostate Cancer AJCC v8
Stage IIIC Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Interventions
Biological: Gonadotrophin Releasing Hormone
Radiation: Intensity-Modulated Radiation Therapy
Procedure: Magnetic Resonance Imaging
First Posted Date
2019-07-30
Last Posted Date
2025-03-07
Lead Sponsor
NRG Oncology
Target Recruit Count
18
Registration Number
NCT04037254
Locations
🇺🇸

Benefis Sletten Cancer Institute, Great Falls, Montana, United States

🇺🇸

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

🇺🇸

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

and more 92 locations

Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol

Phase 1
Recruiting
Conditions
Malignant Solid Neoplasm
Interventions
Procedure: Biospecimen Collection
First Posted Date
2019-06-25
Last Posted Date
2025-05-16
Lead Sponsor
NRG Oncology
Target Recruit Count
350
Registration Number
NCT03997370
Locations
🇺🇸

University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States

🇺🇸

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

🇺🇸

Banner University Medical Center - Tucson, Tucson, Arizona, United States

and more 176 locations

Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy

Not Applicable
Active, not recruiting
Conditions
Prostate Adenocarcinoma
Interventions
Other: Questionnaire Administration
Other: Survivorship Care Plan (SCP)
Other: Treatment Plan
First Posted Date
2019-03-04
Last Posted Date
2025-03-07
Lead Sponsor
NRG Oncology
Target Recruit Count
546
Registration Number
NCT03860961
Locations
🇺🇸

SSM Health Good Samaritan, Mount Vernon, Illinois, United States

🇺🇸

Kingman Regional Medical Center, Kingman, Arizona, United States

🇺🇸

Kaiser Permanente Dublin, Dublin, California, United States

and more 76 locations
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