NRG Oncology

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 2014-01-01

Employees: 51

Market Cap: -

Website: http://www.nrgoncology.org

Clinical Trials

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Phase 3

Recruiting

Conditions: Clinical Stage I Esophageal Adenocarcinoma AJCC v8
Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8
Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage II Esophageal Adenocarcinoma AJCC v8
Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8
Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8

Interventions: Drug: Carboplatin
Procedure: Esophagectomy
Drug: Paclitaxel
Radiation: Intensity-Modulated Radiation Therapy
Radiation: Proton Beam Radiation Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Drug: FOLFOX regimen
Drug: CAPOX regimen
Drug: Docetaxel
Drug: 5FU

First Posted Date: 2019-01-14

Last Posted Date: 2025-01-22

Lead Sponsor: NRG Oncology

Target Recruit Count: 300

Registration Number: NCT03801876

Locations: 🇺🇸
Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States
🇺🇸
Miami Cancer Institute, Miami, Florida, United States
🇺🇸
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois, United States

and more 87 locations

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Phase 2

Active, not recruiting

Conditions: Recurrent Prostate Carcinoma
Stage III Prostate Adenocarcinoma AJCC v7
Stage IV Prostate Adenocarcinoma AJCC v7

Interventions: Radiation: External Beam Radiation Therapy
Drug: Apalutamide
Other: Placebo Administration

First Posted Date: 2017-12-13

Last Posted Date: 2025-05-07

Lead Sponsor: NRG Oncology

Target Recruit Count: 324

Registration Number: NCT03371719

Locations: 🇺🇸
MaineHealth Stephens Hospital, Norway, Maine, United States
🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
🇺🇸
Nebraska Methodist Hospital, Omaha, Nebraska, United States

and more 360 locations

Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer

Phase 3

Active, not recruiting

Conditions: Stage II Prostate Adenocarcinoma

Interventions: Radiation: Stereotactic Body Radiation Therapy (SBRT)
Radiation: Intensity-Modulated Radiation Therapy (IMRT)

First Posted Date: 2017-12-11

Last Posted Date: 2025-03-05

Lead Sponsor: NRG Oncology

Target Recruit Count: 698

Registration Number: NCT03367702

Locations: 🇺🇸
Stanford Cancer Institute Palo Alto, Palo Alto, California, United States
🇺🇸
Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California, United States
🇺🇸
Mercy Cancer Center - Rocklin, Rocklin, California, United States

and more 290 locations

Hypofractionated Radiation Therapy or Conventional Radiation Therapy After Surgery in Treating Patients With Prostate Cancer

Phase 3

Active, not recruiting

Conditions: Prostate Adenocarcinoma
Stage I Prostate Adenocarcinoma AJCC v7
Stage II Prostate Adenocarcinoma AJCC v7
Stage III Prostate Adenocarcinoma AJCC v7

Interventions: Radiation: Hypofractionated radiation therapy
Radiation: Conventional radiation therapy
Drug: Optional androgen deprivation therapy

First Posted Date: 2017-09-07

Last Posted Date: 2025-05-13

Lead Sponsor: NRG Oncology

Target Recruit Count: 296

Registration Number: NCT03274687

Locations: 🇺🇸
Iowa Methodist Medical Center, Des Moines, Iowa, United States
🇺🇸
Mayo Clinic in Florida, Jacksonville, Florida, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

and more 238 locations

Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

Phase 2

Completed

Conditions: Stage IIA Breast Cancer
Stage IIIA Breast Cancer
Invasive Breast Carcinoma
Stage II Breast Cancer
Stage IIB Breast Cancer

Interventions: Procedure: Biopsy of Breast

First Posted Date: 2017-06-15

Last Posted Date: 2025-05-22

Lead Sponsor: NRG Oncology

Target Recruit Count: 105

Registration Number: NCT03188393

Locations: 🇺🇸
Anne Arundel Medical Center, Annapolis, Maryland, United States
🇺🇸
Emory Saint Joseph's Hospital, Atlanta, Georgia, United States
🇺🇸
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

and more 378 locations

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

Phase 3

Recruiting

Conditions: Recurrent Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v7
Unresectable Hepatocellular Carcinoma

Interventions: Radiation: Photon Therapy (Radiation Therapy)
Radiation: Proton Therapy (Radiation Therapy)

First Posted Date: 2017-06-14

Last Posted Date: 2025-05-07

Lead Sponsor: NRG Oncology

Target Recruit Count: 186

Registration Number: NCT03186898

Locations: 🇺🇸
Emory Proton Therapy Center, Atlanta, Georgia, United States
🇺🇸
Emory University Hospital Midtown, Atlanta, Georgia, United States
🇺🇸
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

and more 23 locations

Bupropion Hydrochloride in Improving Sexual Desire in Women With Breast or Gynecologic Cancer

Phase 2

Completed

Conditions: Uterine Corpus Cancer
Vaginal Carcinoma
Ovarian Carcinoma
Postmenopausal
Vulvar Carcinoma
Breast Carcinoma
Cervical Carcinoma

Interventions: Drug: Bupropion 150 mg XL
Drug: Placebo

First Posted Date: 2017-06-08

Last Posted Date: 2022-03-08

Lead Sponsor: NRG Oncology

Target Recruit Count: 230

Registration Number: NCT03180294

Locations: 🇺🇸
Trinity Regional Medical Center, Fort Dodge, Iowa, United States
🇺🇸
Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States
🇺🇸
Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin, United States

and more 359 locations

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Phase 3

Recruiting

Conditions: Grade 2 Meningioma
Intracranial Meningioma

Interventions: Radiation: Radiation Therapy
Other: Clinical Observation

First Posted Date: 2017-06-08

Last Posted Date: 2025-05-07

Lead Sponsor: NRG Oncology

Target Recruit Count: 163

Registration Number: NCT03180268

Locations: 🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Saint Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
🇺🇸
Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States

and more 205 locations

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Phase 2

Active, not recruiting

Conditions: Glioma
Anaplastic Astrocytoma
Anaplastic Oligoastrocytoma
Anaplastic Oligodendroglioma
Diffuse Astrocytoma
Oligoastrocytoma
Oligodendroglioma
WHO Grade 3 Glioma

Interventions: Procedure: Biospecimen Collection
Other: Laboratory Biomarker Analysis
Radiation: Intensity-Modulated Radiation Therapy
Procedure: Magnetic Resonance Imaging
Radiation: Proton Beam Radiation Therapy
Other: Quality-of-Life Assessment
Other: Questionnaire Administration
Drug: Temozolomide

First Posted Date: 2017-06-08

Last Posted Date: 2025-05-09

Lead Sponsor: NRG Oncology

Target Recruit Count: 120

Registration Number: NCT03180502

Locations: 🇺🇸
MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine, United States
🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Boca Raton Regional Hospital, Boca Raton, Florida, United States

and more 31 locations

Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Phase 2

Active, not recruiting

Conditions: Recurrent Non-Small Cell Lung Carcinoma
Stage IV Non-Small Cell Lung Cancer

Interventions: Drug: Docetaxel
Radiation: 3-Dimensional Conformal Radiation Therapy (3D-CRT)
Drug: Gemcitabine
Drug: Pemetrexed Disodium
Drug: Erlotinib Hydrochloride
Radiation: Intensity-Modulated Radiation Therapy (IMRT)
Drug: Pembrolizumab
Radiation: Stereotactic Body Radiation Therapy (SBRT)

First Posted Date: 2017-05-03

Last Posted Date: 2025-03-11

Lead Sponsor: NRG Oncology

Target Recruit Count: 218

Registration Number: NCT03137771

Locations: 🇺🇸
Arizona Center for Cancer Care - Gilbert, Gilbert, Arizona, United States
🇺🇸
Arizona Center for Cancer Care - Scottsdale, Scottsdale, Arizona, United States
🇺🇸
Los Angeles General Medical Center, Los Angeles, California, United States

and more 298 locations

Home Terms & Conditions Privacy Policy