VA Office of Research and Development

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Clinical Trials

Using Emotion Regulation to Decrease Aggression in Veterans With PTSD

Not Applicable

Completed

Conditions: Chronic Post-Traumatic Stress Disorder

Interventions: Behavioral: Manage Emotions to Reduce Aggression (MERA)

First Posted Date: 2016-03-31

Last Posted Date: 2019-09-17

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 24

Registration Number: NCT02724787

Locations: 🇺🇸
James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida, United States

Biological Signatures, Probiotic Among Those With mTBI and PTSD

Phase 1

Completed

Conditions: Post Traumatic Stress Disorder
Mild Traumatic Brain Injury

Interventions: Other: Sunflower and medium chain triglyceride oils
Dietary Supplement: of Lactobacillus reuteri (L. reuteri; DSM 17938)

First Posted Date: 2016-03-30

Last Posted Date: 2020-08-18

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 75

Registration Number: NCT02723344

Locations: 🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado, United States

Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea

Not Applicable

Terminated

Conditions: Obstructive Sleep Apnea
Overweight

Interventions: Behavioral: Exercise + Weight Loss
Behavioral: Weight Loss
Behavioral: Exercise

First Posted Date: 2016-03-29

Last Posted Date: 2021-05-06

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 52

Registration Number: NCT02721251

Locations: 🇺🇸
Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona, United States

Cognitive-Behavioral Conjoint Therapy (CBCT) Project

Not Applicable

Completed

Conditions: Post Traumatic Stress Disorder

Interventions: Behavioral: CBCT-Office Based (CBCT-OB)
Behavioral: PTSD Family Education (PFE)
Behavioral: CBCT-Home Based (CBCT-HB)

First Posted Date: 2016-03-25

Last Posted Date: 2022-03-07

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 274

Registration Number: NCT02720016

Locations: 🇺🇸
VA San Diego Healthcare System, San Diego, CA, San Diego, California, United States

Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid

Phase 2

Completed

Conditions: Alzheimer's Disease

Interventions: Drug: icosapent ethyl (IPE)
Other: gel cap placebo

First Posted Date: 2016-03-25

Last Posted Date: 2024-11-26

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 131

Registration Number: NCT02719327

Locations: 🇺🇸
William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison, Wisconsin, United States

Benefits of Physical Exercise in Schizophrenia

Not Applicable

Completed

Conditions: Schizophrenia

Interventions: Behavioral: Physical exercise
Behavioral: Stretching exercise

First Posted Date: 2016-03-23

Last Posted Date: 2019-09-19

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 53

Registration Number: NCT02716584

Locations: 🇺🇸
VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles, California, United States

Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics

Completed

Conditions: Depressive Disorders
Alcohol Use Disorders
Post-traumatic Stress Disorder (PTSD)

Interventions: Other: Blended Telemedicine-Based Integrated Care
Other: Usual Care

First Posted Date: 2016-03-18

Last Posted Date: 2024-07-18

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 318

Registration Number: NCT02713217

Locations: 🇺🇸
Central Arkansas Veterans Healthcare System Eugene J. Towbin Healthcare Center, Little Rock, AR, North Little Rock, Arkansas, United States

Advancing Symptom Alleviation With Palliative Treatment

Not Applicable

Completed

Conditions: Pulmonary Fibrosis, Interstitial Lung Disease
Heart Failure
Pulmonary Disease, Chronic Obstructive
Emphysema

Interventions: Behavioral: ADAPT Intervention

First Posted Date: 2016-03-18

Last Posted Date: 2024-08-09

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 306

Registration Number: NCT02713347

Locations: 🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado, United States
🇺🇸
VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington, United States

Sleep Apnea in Elderly

Phase 4

Recruiting

Conditions: Sleep Apnea
Elderly Adults

Interventions: Other: Hyperoxia/oxygen
Drug: Finasteride
Drug: Acetazolamide

First Posted Date: 2016-03-09

Last Posted Date: 2024-07-17

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 100

Registration Number: NCT02703220

Locations: 🇺🇸
John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan, United States

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

Not Applicable

Recruiting

Conditions: OSA COPD Overlap Syndrome
Obstructive Sleep Apnea

Interventions: Device: Positive airway pressure
Device: NIPPV and /or oxygen

First Posted Date: 2016-03-09

Last Posted Date: 2024-10-03

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 108

Registration Number: NCT02703207

Locations: 🇺🇸
John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan, United States

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