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Cytosorbents

🇺🇸United States
Ownership
-
Employees
186
Market Cap
$56.6M
Website
Introduction

CytoSorbents Corp. engages in critical care immunotherapy, investigation, and commercialization of blood purification technology. Its product portfolio includes CytoSorb, ContrastSorb XL, HemoDefend, VetResQ, and DrugSorb. The company was founded by Joseph Rubin in August 1997 and is headquartered in Princeton, NJ.

Clinical Trials

10

Active:0
Completed:4

Trial Phases

2 Phases

Phase 2:1
Not Applicable:5

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (6 trials with phase data)• Click on a phase to view related trials

Not Applicable
5 (83.3%)
Phase 2
1 (16.7%)

CytOSorb TreatMent Of Critically Ill PatientS Registry

Recruiting
Conditions
Cardiogenic Shock
Pancreatitis
Extracorporeal Life Support
Postoperative Endocarditis
Postoperative Vasoplegic Syndrome
Hemophagocytic Lymphohistiocytoses
Trauma
Rhabdomyolysis
Acute on Chronic Liver Failure
Liver Transplant; Complications
First Posted Date
2021-12-06
Last Posted Date
2025-05-21
Lead Sponsor
CytoSorbents, Inc
Target Recruit Count
3000
Registration Number
NCT05146336
Locations
🇦🇹

Klinikum Klagenfurt am Wörthersee, Klagenfurt, Austria

🇦🇹

Medizinische Universität Wien, Wien, Austria

🇩🇪

Universitätsklinikum Aachen, Aachen, Germany

and more 24 locations

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

Not Applicable
Terminated
Conditions
Blood Loss, Postoperative
Hemorrhage Postoperative
Hemorrhage, Surgical
Blood Loss, Surgical
First Posted Date
2021-10-26
Last Posted Date
2025-05-04
Lead Sponsor
CytoSorbents, Inc
Target Recruit Count
9
Registration Number
NCT05093504
Locations
🇺🇸

University of California, Davis Medical Center, Sacramento, California, United States

🇺🇸

University of Colorado, Denver, Colorado, United States

🇺🇸

Yale University, New Haven, Connecticut, United States

and more 24 locations

Safe and Timely Antithrombotic Removal (STAR) Registry

Recruiting
Conditions
Blood Loss, Surgical
Blood Loss, Postoperative
Hemorrhage, Surgical
Hemorrhage Postoperative
First Posted Date
2021-10-14
Last Posted Date
2025-07-01
Lead Sponsor
CytoSorbents, Inc
Target Recruit Count
1000
Registration Number
NCT05077124
Locations
🇦🇹

Universitätsklinikum Graz, Graz, Austria

🇦🇹

Medizinische Universität Innsbruck, Innsbruck, Austria

🇦🇹

Klinikum Klagenfurt am Wörthersee, Klagenfurt, Austria

and more 27 locations

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

Not Applicable
Completed
Conditions
Blood Loss, Postoperative
Hemorrhage Postoperative
Blood Loss, Surgical
Hemorrhage, Surgical
First Posted Date
2021-07-26
Last Posted Date
2025-04-11
Lead Sponsor
CytoSorbents, Inc
Target Recruit Count
140
Registration Number
NCT04976530
Locations
🇺🇸

University of California, Davis Medical Center, Sacramento, California, United States

🇺🇸

Yale New Haven Hospital, New Haven, Connecticut, United States

🇺🇸

MedStar Health Research Institute, Washington, District of Columbia, United States

and more 26 locations

Registry of CytoSorb Therapy in COVID-19 ICU Patients

Completed
Conditions
COVID-19
First Posted Date
2020-05-18
Last Posted Date
2024-02-09
Lead Sponsor
CytoSorbents, Inc
Target Recruit Count
138
Registration Number
NCT04391920
Locations
🇺🇸

Medical Center of Aurora, Aurora, Colorado, United States

🇺🇸

University of Chicago Medicine, Chicago, Illinois, United States

🇺🇸

Franciscan Health Indianapolis, Indianapolis, Indiana, United States

and more 4 locations
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News

FDA Denies CytoSorbents' De Novo Request for DrugSorb-ATR Blood Purification Device

The FDA has issued a denial letter for CytoSorbents' DrugSorb-ATR device, designed to reduce bleeding in CABG surgery patients who recently took ticagrelor, citing unresolved deficiencies.

CytoSorbents Seeks Approval for DrugSorb-ATR in Canada to Reduce Bleeding in Heart Surgery

CytoSorbents has submitted a Medical Device License application to Health Canada for DrugSorb-ATR, targeting reduced bleeding during CABG surgery in patients on ticagrelor.

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