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Soligenix

Soligenix logo
🇺🇸United States
Ownership
Public
Established
1987-01-01
Employees
15
Market Cap
$8.8M
Website
http://www.soligenix.com
Introduction

Soligenix, Inc. is a late-stage biopharmaceutical company, which engages in the development and commercialization of products to treat rare diseases. It operates through the Specialized BioTherapeutics and Public Health Solutions segments. The Specialized BioTherapeutics segment focuses on the development of a novel photodynamic therapy (SGX301) utilizing topical synthetic hypericin activated with safe visible fluorescent light for the treatment of cutaneous T-cell lymphoma. The Public Health Solutions segment consists of active development programs for RiVax, a ricin toxin vaccine candidate, and SGX943, a therapeutic candidate for antibiotic resistant and emerging infectious disease. The company was founded in 1987 and is headquartered Princeton, NJ.

Clinical Trials

14

Active:2
Completed:6

Trial Phases

3 Phases

Phase 1:2
Phase 2:6
Phase 3:5

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (13 trials with phase data)• Click on a phase to view related trials

Phase 2
6 (46.2%)
Phase 3
5 (38.5%)
Phase 1
2 (15.4%)

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

Phase 3
Recruiting
Conditions
Mycosis Fungoides
Cutaneous T Cell Lymphoma
CTCL/ Mycosis Fungoides
CTCL
Interventions
Drug: Placebo
First Posted Date
2024-06-24
Last Posted Date
2025-07-04
Lead Sponsor
Soligenix
Target Recruit Count
80
Registration Number
NCT06470451
Locations
🇺🇸

Medical Dermatology Specialists, Phoenix, Arizona, United States

🇺🇸

Mayo Clinic, Scottsdale, Arizona, United States

🇺🇸

Therapeutics Clinical Research, San Diego, California, United States

and more 13 locations

Dusquetide for the Treatment of Behcet's Disease

Phase 2
Recruiting
Conditions
Behçet Disease
Interventions
First Posted Date
2024-04-26
Last Posted Date
2025-03-28
Lead Sponsor
Soligenix
Target Recruit Count
25
Registration Number
NCT06386744
Locations
🇹🇷

Istanbul University - Cerrahpasa, Cerrahpasa School of Medicine, Istanbul, Turkey

HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL

Phase 2
Completed
Conditions
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Interventions
First Posted Date
2023-11-28
Last Posted Date
2024-07-03
Lead Sponsor
Soligenix
Target Recruit Count
10
Registration Number
NCT06149247
Locations
🇺🇸

Rochester Skin Lymphoma Medical Group, Fairport, New York, United States

Topical SGX302 for Mild-to-Moderate Psoriasis

Phase 2
Recruiting
Conditions
Plaque Psoriasis
Psoriasis
Psoriasis Vulgaris
Interventions
Drug: Placebo
First Posted Date
2022-07-01
Last Posted Date
2025-06-05
Lead Sponsor
Soligenix
Target Recruit Count
47
Registration Number
NCT05442190
Locations
🇺🇸

Therapeutics Clinical Research, San Diego, California, United States

PK and ECG Determinations Following 8 Weeks of HyBryte Treatment for Cutaneous T-Cell Lymphoma

Phase 2
Completed
Conditions
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Interventions
First Posted Date
2022-05-19
Last Posted Date
2023-06-07
Lead Sponsor
Soligenix
Target Recruit Count
9
Registration Number
NCT05380635
Locations
🇺🇸

Rochester Skin Lymphoma Medical Group, Fairport, New York, United States

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News

Soligenix Completes Manufacturing Transfer of Synthetic Hypericin for Rare Skin Cancer Treatment

Soligenix successfully transferred manufacturing of synthetic hypericin from Europe to the U.S. through partnership with Sterling Pharma Solutions, establishing scalable cGMP production for clinical trials.

HyBryte Shows Sustained Improvement in CTCL Lesions Post-Treatment

Soligenix's HyBryte demonstrated continued improvement in cutaneous T-cell lymphoma (CTCL) lesions even after treatment cessation.

Soligenix's HyBryte Enrolls First Patients in Phase 3 CTCL Trial

Soligenix initiates patient enrollment for the confirmatory Phase 3 FLASH2 trial of HyBryte for cutaneous T-cell lymphoma (CTCL).

Soligenix Forms European Medical Advisory Board for HyBryte CTCL Trial

Soligenix has established a European Medical Advisory Board (MAB) to guide its Phase 3 trial of HyBryte™ for cutaneous T-cell lymphoma (CTCL).

Soligenix Establishes European Medical Advisory Board for HyBryte™ CTCL Phase 3 Trial

Soligenix has formed a European Medical Advisory Board (MAB) to guide the Phase 3 trial of HyBryte™ for cutaneous T-cell lymphoma (CTCL).

Soligenix Launches Phase 2 Trial of SGX945 (Dusquetide) for Behçet's Disease

Soligenix has initiated a Phase 2 clinical trial to evaluate SGX945 (dusquetide) for treating aphthous ulcers associated with Behçet's Disease, a chronic auto-immune condition.

Soligenix Launches Phase 2 Trial of SGX945 (Dusquetide) for Behçet's Disease

Soligenix has initiated a Phase 2 clinical trial to evaluate SGX945 (dusquetide) for treating aphthous ulcers associated with Behçet's Disease.

Soligenix Initiates Phase 2 Trial of SGX945 (Dusquetide) for Behçet's Disease

Soligenix has commenced patient enrollment in a Phase 2 clinical trial to evaluate SGX945 (dusquetide) for the treatment of Behçet's Disease.

Soligenix Initiates Phase 2 Trial of Dusquetide (SGX945) for Behçet's Disease

Soligenix has commenced patient enrollment in a Phase 2 clinical trial evaluating SGX945 (dusquetide) for the treatment of Behçet's Disease.

Soligenix to Initiate Phase 3 Trial of HyBryte for Cutaneous T Cell Lymphoma

Soligenix is set to begin a Phase 3 trial (FLASH2) of HyBryte for cutaneous T cell lymphoma (CTCL) treatment before the end of 2024, mirroring the design of the previous FLASH trial.

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