JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Acute Coronary Syndrome KCMC_1

Not Applicable

Active, not recruiting

Conditions: Hypertension
HIV

Interventions: Behavioral: Community Health Worker (CHW)-delivered Hypertension Management Pilot (CHAMP)
Behavioral: Control of Blood Pressure and Risk Attenuation (COBRA)

First Posted Date: 2024-07-16

Last Posted Date: 2025-05-14

Lead Sponsor: Duke University

Target Recruit Count: 100

Registration Number: NCT06503991

Locations: 🇹🇿
KCMC, Moshi, Tanzania

PrEP (Pre-exposure Prophylaxis) Stigma and Women Ethnodrama Pre-Test Phase

Not Applicable

Recruiting

Conditions: HIV

Interventions: Behavioral: Ethnodrama Intervention

First Posted Date: 2024-07-15

Last Posted Date: 2025-01-28

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06501885

Locations: 🇰🇪
Impact Research and Development, Kisumu, Kenya

Detecting Traumatic Intracranial Hemorrhage With the InfraScanner 2500™ in Uganda

Not Applicable

Completed

Conditions: Head Trauma
Crushing Skull Injury
Head Injury Major
Injury, Head
Head Injury
Head Injuries, Multiple
Head Trauma, Penetrating
Craniocerebral Injury
Head Trauma,Closed
Trauma, Head

Interventions: Device: InfraScanner 2500™

First Posted Date: 2024-07-08

Last Posted Date: 2025-04-23

Lead Sponsor: Duke University

Target Recruit Count: 180

Registration Number: NCT06491173

Locations: 🇺🇬
Mayanja Memorial Hospital, Mbarara, Uganda
🇺🇬
Mbarara Regional Referral Hospital, Mbarara, Uganda

Single Dose Texas 2017 (H3N2) Challenge Study

Phase 1

Completed

Conditions: Influenza Viral Infections

Interventions: Biological: Sham placebo
Biological: Influenza A/Texas/71/2017 (H3N2)

First Posted Date: 2024-06-26

Last Posted Date: 2025-02-26

Lead Sponsor: Duke University

Target Recruit Count: 33

Registration Number: NCT06476275

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

RIC (Remote Ischemic Conditioning) in Older Individuals

Not Applicable

Conditions: Old Age
Mobility Limitation
Debility

Interventions: Other: Low-intensity resistance exercise training
Other: Remote ischemic conditioning (RIC)

First Posted Date: 2024-06-26

Last Posted Date: 2024-10-18

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06476288

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?

Not Applicable

Recruiting

Conditions: ASCVD
LDL-C

Interventions: Other: Care Champion Intervention

First Posted Date: 2024-06-24

Last Posted Date: 2024-10-18

Lead Sponsor: Duke University

Target Recruit Count: 400

Registration Number: NCT06471036

Locations: 🇺🇸
Allina Health, Minneapolis, Minnesota, United States

Role of Aging and Individual Variation in Exercise Training Responsiveness

Not Applicable

Recruiting

Conditions: Obesity
Prediabetic State
Cardiovascular Diseases
Insulin Resistance

Interventions: Behavioral: High/Vig
Behavioral: Low/Mod
Behavioral: High/Mod

First Posted Date: 2024-06-24

Last Posted Date: 2025-05-11

Lead Sponsor: Duke University

Target Recruit Count: 8

Registration Number: NCT06471569

Locations: 🇺🇸
Duke Center for Living, Durham, North Carolina, United States

Safety, Tolerability and Efficacy of JCXH-211 in Patients With Recurrent or Progressive High-Grade Glioma

Phase 1

Not yet recruiting

Conditions: Recurrent or Progressive High-grade Glioma

Interventions: Biological: JCXH-211

First Posted Date: 2024-06-21

Last Posted Date: 2025-03-05

Lead Sponsor: Duke University

Target Recruit Count: 21

Registration Number: NCT06468605

LiveWell: Adapted DBT Skills Training for Metastatic Lung Cancer

Not Applicable

Recruiting

Conditions: Cancer Metastatic to Lung

First Posted Date: 2024-06-18

Last Posted Date: 2025-06-05

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT06464562

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Black Resilient Caregivers

Not Applicable

Recruiting

Conditions: Obesity, Childhood

Interventions: Behavioral: AARC

First Posted Date: 2024-06-14

Last Posted Date: 2025-04-10

Lead Sponsor: Duke University

Target Recruit Count: 24

Registration Number: NCT06458790

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

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