JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya

Not Applicable

Completed

Conditions: Parenting
Mental Health Issue
Adolescent - Emotional Problem
Child Behavior
Parent-Child Relations
Family Relations
Family Conflict
Adolescent Problem Behavior
Child Abuse
Marital Conflict

Interventions: Behavioral: Tuko Pamoja, "We are Together" in Kiswahili

First Posted Date: 2024-05-16

Last Posted Date: 2025-03-07

Lead Sponsor: Duke University

Target Recruit Count: 240

Registration Number: NCT06417918

Locations: 🇰🇪
Moi University, Eldoret, Kenya

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Phase 2

Recruiting

Conditions: Long COVID
Long COVID-19
Sleep Disturbance

Interventions: Drug: Melantonin Placebo
Drug: Melatonin
Device: Tailored lighting (TL) Active
Device: Tailored lighting (TL) Placebo

First Posted Date: 2024-05-08

Last Posted Date: 2025-04-23

Lead Sponsor: Duke University

Target Recruit Count: 600

Registration Number: NCT06404112

Locations: 🇺🇸
All sites listed under NCT06404086, Durham, North Carolina, United States

RECOVER-ENERGIZE Platform Protocol

Not Applicable

Recruiting

Conditions: Long Covid-19
Long Covid19
Long COVID

Interventions: Behavioral: Personalized Cardiopulmonary Rehabilitation
Behavioral: Structured Pacing
Other: Usual Care
Other: Education

First Posted Date: 2024-05-08

Last Posted Date: 2025-05-21

Lead Sponsor: Duke University

Target Recruit Count: 660

Registration Number: NCT06404047

Locations: 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Banner University Medical Center Phoenix, Phoenix, Arizona, United States
🇺🇸
Rush University Medical Center, Chicago, Illinois, United States

and more 39 locations

RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)

Not Applicable

Recruiting

Conditions: Long COVID
Long Covid19
Long Covid-19

Interventions: Behavioral: Personalized Cardiopulmonary Rehabilitation
Other: Education

First Posted Date: 2024-05-08

Last Posted Date: 2025-05-20

Lead Sponsor: Duke University

Target Recruit Count: 360

Registration Number: NCT06404060

Locations: 🇺🇸
All sites listed under NCT06404047, Durham, North Carolina, United States

RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))

Not Applicable

Active, not recruiting

Conditions: Long Covid19
Long COVID
Long Covid-19

Interventions: Other: Usual Care
Behavioral: Structured Pacing

First Posted Date: 2024-05-08

Last Posted Date: 2025-05-23

Lead Sponsor: Duke University

Target Recruit Count: 300

Registration Number: NCT06404073

Locations: 🇺🇸
All sites listed under NCT06404047, Durham, North Carolina, United States

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Phase 2

Recruiting

Conditions: Long COVID-19
Long COVID
Hypersomnia

Interventions: Drug: Modafinil Placebo
Drug: Modafinil
Drug: Solriamfetol
Drug: Solriamfetol Placebo

First Posted Date: 2024-05-08

Last Posted Date: 2025-04-23

Lead Sponsor: Duke University

Target Recruit Count: 474

Registration Number: NCT06404099

Locations: 🇺🇸
All sites listed under NCT06404086, Durham, North Carolina, United States

RECOVER-SLEEP: Platform Protocol

Phase 2

Recruiting

Conditions: Long COVID
Long COVID-19
Hypersomnia
Sleep Disturbance

Interventions: Drug: Melatonin
Drug: Modafinil
Drug: Melantonin Placebo
Drug: Modafinil Placebo
Device: Tailored lighting (TL) Active
Drug: Solriamfetol
Device: Tailored lighting (TL) Placebo
Drug: Solriamfetol Placebo

First Posted Date: 2024-05-08

Last Posted Date: 2025-04-23

Lead Sponsor: Duke University

Target Recruit Count: 1074

Registration Number: NCT06404086

Locations: 🇺🇸
Banner University Medical Center Phoenix, Phoenix, Arizona, United States
🇺🇸
University of Arizona Banner Medical Center, Tucson, Arizona, United States
🇺🇸
University of California San Francisco General Hospital, San Francisco, California, United States

and more 42 locations

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Recruiting

Conditions: Lung Transplant; Infection or Inflammation
Lung Transplant; Complications
Lung Transplant Failure
Lung Transplant Rejection

First Posted Date: 2024-05-03

Last Posted Date: 2024-10-08

Lead Sponsor: Duke University

Target Recruit Count: 2600

Registration Number: NCT06399302

Locations: 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
🇺🇸
University of California at San Francisco, San Francisco, California, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

ACT for Infertility: Case Series

Not Applicable

Active, not recruiting

Conditions: Psychological Distress
Acceptance and Commitment Therapy
Infertility
Psychological Flexibility

Interventions: Behavioral: Acceptance and Commitment Therapy

First Posted Date: 2024-04-29

Last Posted Date: 2025-05-18

Lead Sponsor: Duke University

Target Recruit Count: 9

Registration Number: NCT06388044

Locations: 🇺🇸
Duke North Pavilion, Durham, North Carolina, United States

TOP 2301: Neoadjuvant Chemo for NSCLC

Phase 2

Recruiting

Conditions: Non Small Cell Lung Cancer

Interventions: Drug: Cemiplimab
Drug: Alirocumab
Drug: Chemotherapy

First Posted Date: 2024-04-26

Last Posted Date: 2025-03-25

Lead Sponsor: Duke University

Target Recruit Count: 126

Registration Number: NCT06385262

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

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