JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia

Early Phase 1

Terminated

Conditions: Focus is Determination of the Role of SNO-Hb in Forearm Blood Flow Regulation

Interventions: Drug: Oral N-acetylcysteine

First Posted Date: 2013-07-23

Last Posted Date: 2016-12-29

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT01905696

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Negative Pressure Wound Therapy to Reduce Surgical Site Infection

Not Applicable

Completed

Conditions: Patients Undergoing Hepatopancreatobiliary Surgery

Interventions: Device: Negative pressure wound therapy
Device: Conventional wound therapy

First Posted Date: 2013-07-23

Last Posted Date: 2022-12-02

Lead Sponsor: Duke University

Target Recruit Count: 164

Registration Number: NCT01905397

Locations: 🇺🇸
Indiana University, Indianapolis, Indiana, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Amphetamine-Enhanced Stroke Recovery

Phase 2

Completed

Conditions: Stroke

Interventions: Drug: Dextroamphetamine
Other: Physical Therapy
Drug: Placebo

First Posted Date: 2013-07-23

Last Posted Date: 2013-07-23

Lead Sponsor: Duke University

Target Recruit Count: 99

Registration Number: NCT01905371

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Development of Novel Therapies for NIDDM

Not Applicable

Completed

Conditions: Metabolism

Interventions: Other: 3 Tesla
Other: 7 Tesla

First Posted Date: 2013-07-23

Last Posted Date: 2019-05-31

Lead Sponsor: Duke University

Target Recruit Count: 64

Registration Number: NCT01905722

Locations: 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States

Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant

Completed

Conditions: Myeloma
Leukemia
Myelodysplasia
Hodgkin's Disease
Non Hodgkin's Lymphoma

First Posted Date: 2013-07-22

Last Posted Date: 2016-05-05

Lead Sponsor: Duke University

Target Recruit Count: 48

Registration Number: NCT01904175

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity

Not Applicable

Completed

Conditions: Extracorporeal Membrane Oxygenation

Interventions: Biological: Fresh frozen plasma

First Posted Date: 2013-07-19

Last Posted Date: 2017-06-27

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT01903863

Locations: 🇺🇸
Duke University Medical Center PICU and PCICU, Durham, North Carolina, United States

Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly

Not Applicable

Completed

Conditions: Elderly
Sedentary

Interventions: Other: Regional Specific Training Stimulus (RSTS)
Other: Aerobic Exercise Regimen (AE)

First Posted Date: 2013-07-15

Last Posted Date: 2014-03-04

Lead Sponsor: Duke University

Target Recruit Count: 108

Registration Number: NCT01899586

Locations: 🇺🇸
Duke Center for Living; Wallace Clinic, Durham, North Carolina, United States
🇺🇸
Pennington Biomedical Center, Baton Rouge, Louisiana, United States

Virtual Reality for Osteoarthritis Knee Pain Pilot

Not Applicable

Terminated

Conditions: Osteoarthritis of the Knee

Interventions: Procedure: Virtual Reality Training Session
Device: 3D viewer with iPod Touch/iPhone (or similar smartphone)

First Posted Date: 2013-07-15

Last Posted Date: 2023-08-07

Lead Sponsor: Duke University

Target Recruit Count: 4

Registration Number: NCT01899508

Locations: 🇺🇸
Duke University Medical Center department Psychiatry, Durham, North Carolina, United States

Triadic Expectations: Decision Making in the Context of Cancer Treatment

Completed

Conditions: Health Care Decision Making

First Posted Date: 2013-07-12

Last Posted Date: 2014-02-06

Lead Sponsor: Duke University

Target Recruit Count: 38

Registration Number: NCT01898481

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Feasibility of Blood Oxygenation Level-Dependent Contrast (BOLD) Breast MRI Induced by Breath- Holding

Completed

Conditions: Breast Cancer

First Posted Date: 2013-07-12

Last Posted Date: 2018-08-01

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT01898533

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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