JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Mitigating Racial Disparities in Shared Decision Making in the Intensive Care Unit

Not Applicable

Not yet recruiting

Conditions: Health Care Disparities

Interventions: Behavioral: Shared decision making tip sheet

First Posted Date: 2023-02-02

Last Posted Date: 2025-03-19

Lead Sponsor: Duke University

Target Recruit Count: 106

Registration Number: NCT05710744

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Generating Evidence in ECMO Ventilation Strategies

Not Applicable

Completed

Conditions: Acute Respiratory Failure
ARDS

Interventions: Other: Ultra-Lung Protective Ventilation
Other: Standard-Lung Protective Ventilation

First Posted Date: 2023-02-01

Last Posted Date: 2024-11-21

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT05708365

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Not Applicable

Withdrawn

Conditions: Heart Failure

Interventions: Other: Initial hospitalization-based management strategy
Other: Initial outpatient management strategy, including outpatient IV diuretics in clinic

First Posted Date: 2023-01-30

Last Posted Date: 2025-04-27

Lead Sponsor: Duke University

Target Recruit Count: 70

Registration Number: NCT05704595

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Enhancing Wellness Through Affirming Services and Education

Not Applicable

Recruiting

Conditions: Mental Health Disorder
Substance Use
HIV

Interventions: Behavioral: Comprehensive outpatient behavioral health care

First Posted Date: 2023-01-26

Last Posted Date: 2025-02-28

Lead Sponsor: Duke University

Target Recruit Count: 200

Registration Number: NCT05700474

Locations: 🇺🇸
Susan Reif, Charlotte, North Carolina, United States

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

Suspended

Conditions: Glioblastoma
Glioma, Malignant

First Posted Date: 2023-01-25

Last Posted Date: 2025-05-28

Lead Sponsor: Duke University

Target Recruit Count: 100

Registration Number: NCT05695976

Locations: 🇺🇸
The Preston Robert Tisch Brain Tumor Center at Duke University, Durham, North Carolina, United States

Regional Anesthesia Following Pediatric Cardiac Surgery

Phase 4

Completed

Conditions: Atrial Septal Defect
Ventricular Septal Defect
Pain, Procedural

Interventions: Procedure: Regional Anesthesia
Procedure: Wound infiltration
Drug: Ropivacaine 0.2% Injectable Solution

First Posted Date: 2023-01-18

Last Posted Date: 2025-02-12

Lead Sponsor: Duke University

Target Recruit Count: 52

Registration Number: NCT05688670

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings (PainPac)

Not Applicable

Completed

Conditions: Colorectal Cancer

Interventions: Behavioral: PainPac

First Posted Date: 2023-01-17

Last Posted Date: 2024-12-19

Lead Sponsor: Duke University

Target Recruit Count: 62

Registration Number: NCT05686122

Locations: 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States

Modeling Organ Motion During Abdominal Imaging in Healthy Volunteers

Not Applicable

Completed

Conditions: Healthy Volunteers

Interventions: Other: MRI

First Posted Date: 2023-01-09

Last Posted Date: 2025-01-06

Lead Sponsor: Duke University

Target Recruit Count: 5

Registration Number: NCT05674851

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Mobile Neurofeedback for Low Back Pain

Not Applicable

Recruiting

Conditions: Chronic Low Back Pain

Interventions: Device: Sham (Placebo Control)
Device: Neurofeedback

First Posted Date: 2022-12-30

Last Posted Date: 2024-10-11

Lead Sponsor: Duke University

Target Recruit Count: 150

Registration Number: NCT05669027

Locations: 🇺🇸
Duke University Medical Center, Department of Psychiatry, Durham, North Carolina, United States

ESP Block for Post Cesarean Analgesia

Phase 4

Completed

Conditions: Cesarean Section Complications

Interventions: Procedure: Erector Spinae Plane (ESP) Block
Drug: bupivacaine liposome injectable suspension
Drug: bupivacaine

First Posted Date: 2022-12-27

Last Posted Date: 2025-02-05

Lead Sponsor: Duke University

Target Recruit Count: 150

Registration Number: NCT05664958

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

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