JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Simultaneous mRNA COVID-19 and IIV4 Vaccination Study

Phase 4

Completed

Conditions: Injection Site Reaction
Quality of Life
Adverse Drug Event
Systemic Reaction

Interventions: Biological: mRNA COVID-19
Biological: IIV4
Other: Placebo (saline)

First Posted Date: 2021-08-31

Last Posted Date: 2024-03-19

Lead Sponsor: Duke University

Target Recruit Count: 348

Registration Number: NCT05028361

Locations: 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
🇺🇸
John Hopkins University, Baltimore, Maryland, United States
🇺🇸
Duke University, Durham, North Carolina, United States

ED90 of 0.75% Bupivacaine for Bilateral Tubal Ligation (BTL)

Phase 4

Withdrawn

Conditions: Pain

Interventions: Drug: Hyperbaric bupivacaine

First Posted Date: 2021-08-24

Last Posted Date: 2022-05-27

Lead Sponsor: Duke University

Registration Number: NCT05017584

Optimizing Parameters of Low-Intensity Focused Ultrasound for Cortical Modulation in Stroke Patients

Not Applicable

Completed

Conditions: Stroke

Interventions: Device: Low Intensity Focused Ultrasonic Stimulation
Device: Low Intensity Focused Ultrasonic Stimulation Frequency

First Posted Date: 2021-08-23

Last Posted Date: 2025-02-27

Lead Sponsor: Duke University

Target Recruit Count: 54

Registration Number: NCT05016531

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Simultaneous RZV and aIIV4 Vaccination

Phase 4

Completed

Conditions: Injection Site Reaction
Adverse Drug Event
Quality of Life
Pain

Interventions: Biological: FLUAD® Quadrivalent
Biological: Fluzone® High-Dose Quadrivalent
Biological: SHINGRIX®

First Posted Date: 2021-08-16

Last Posted Date: 2024-07-11

Lead Sponsor: Duke University

Target Recruit Count: 267

Registration Number: NCT05007041

Locations: 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸
Duke University, Durham, North Carolina, United States

Increasing Vaccine Uptake Among Adolescents in the Rural South

Not Applicable

Completed

Conditions: Vaccine Hesitancy

Interventions: Other: INVEST

First Posted Date: 2021-08-10

Last Posted Date: 2024-12-04

Lead Sponsor: Duke University

Target Recruit Count: 2

Registration Number: NCT04999267

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States
🇺🇸
University of South Carolina, Columbia, South Carolina, United States

1:1 Comparison of the Pocket Colposcope in Kenya

Not Applicable

Completed

Conditions: HPV Infection
HIV Infections
Cervical Cancer

Interventions: Procedure: Standard of Care Colposcopy
Device: Pocket Colposcope

First Posted Date: 2021-08-10

Last Posted Date: 2025-02-19

Lead Sponsor: Duke University

Target Recruit Count: 434

Registration Number: NCT04998318

Locations: 🇰🇪
Kenya Medical Research Institute, Nairobi, Kenya

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

Not Applicable

Recruiting

Conditions: Retinopathy of Prematurity

Interventions: Device: Investigational ultracompact OCT and OCTA system
Device: retinal photographs

First Posted Date: 2021-08-06

Last Posted Date: 2025-03-17

Lead Sponsor: Duke University

Target Recruit Count: 236

Registration Number: NCT04995341

Locations: 🇺🇸
Duke University Eye Center, Durham, North Carolina, United States
🇺🇸
University of Pennsylvania, Center for Preventive Ophthalmology and Biostatistics, Philadelphia, Pennsylvania, United States

Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women

Not Applicable

Recruiting

Conditions: Smoking Cessation
Communication Research
Pregnancy

Interventions: Behavioral: Clinician Communication Intervention
Other: 5A's lecture

First Posted Date: 2021-08-02

Last Posted Date: 2025-05-25

Lead Sponsor: Duke University

Target Recruit Count: 840

Registration Number: NCT04985903

Locations: 🇺🇸
Durham OB, Durham, North Carolina, United States

MPS II Immunophenotyping

Recruiting

Conditions: MPS II
Hunter Syndrome
Mucopolysaccharidosis II

First Posted Date: 2021-07-26

Last Posted Date: 2024-04-22

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT04976231

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

DBT for Metastatic Lung Cancer

Not Applicable

Completed

Conditions: Lung Cancer Metastatic

Interventions: Behavioral: Dialectical Behavioral Therapy Skills Training

First Posted Date: 2021-07-22

Last Posted Date: 2025-04-27

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT04973436

Locations: 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States

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