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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

Phase 2

Completed

Conditions: Stroke, Ischemic
Motor Activity
Upper Extremity Paralysis

Interventions: Device: High dose tDCS
Device: Low dose tDCS
Device: Sham
Behavioral: mCIMT

First Posted Date: 2019-02-01

Last Posted Date: 2025-01-17

Lead Sponsor: Duke University

Target Recruit Count: 129

Registration Number: NCT03826030

Locations: 🇺🇸
Burke Rehabilitation Center, White Plains, New York, United States
🇺🇸
University of Alabama at Birmingham Hospital, Birmingham, Alabama, United States
🇺🇸
Keck Hospital of USC, Los Angeles, California, United States

and more 11 locations

A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)

Not Applicable

Active, not recruiting

Conditions: Hematologic Malignancy

Interventions: Behavioral: Interval training
Behavioral: Psychiatric consult
Behavioral: Referral to Social Worker
Behavioral: Nutrition/diet evaluation

First Posted Date: 2019-01-30

Last Posted Date: 2022-12-20

Lead Sponsor: Duke University

Target Recruit Count: 29

Registration Number: NCT03823651

Locations: 🇺🇸
Duke University Adult Bone Marrow Transplant Clinic, Durham, North Carolina, United States

Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1

Not Applicable

Completed

Conditions: Febrile Illness
Malaria

Interventions: Other: Conditional ACT subsidy, Arm 2 levels
Other: Conditional ACT subsidy, Arm 3 levels
Other: Conditional ACT subsidy, Arm 4 levels
Other: Conditional ACT subsidy, Arm 1 levels

First Posted Date: 2019-01-18

Last Posted Date: 2020-11-12

Lead Sponsor: Duke University

Target Recruit Count: 842

Registration Number: NCT03810014

Locations: 🇰🇪
Moi University, Eldoret, Kenya

ED90 of 3% Chloroprocaine for Cervical Cerclage

Phase 4

Completed

Conditions: Cerclage, Cervical

Interventions: Drug: Chloroprocaine Hcl 3% Inj

First Posted Date: 2019-01-15

Last Posted Date: 2021-10-12

Lead Sponsor: Duke University

Target Recruit Count: 47

Registration Number: NCT03805438

Locations: 🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Lung Transplant Plasmapheresis/Belatacept/Carfilzomib for Antibody Mediated Rejection and Desensitization

Phase 2

Withdrawn

Conditions: Lung Transplant Rejection
Antibody-mediated Rejection

Interventions: Drug: Belatacept
Drug: Carfilzomib

First Posted Date: 2019-01-15

Last Posted Date: 2019-05-02

Lead Sponsor: Duke University

Registration Number: NCT03805178

Walking Gait Biomechanics Following Knee Joint Effusion

Not Applicable

Recruiting

Conditions: Knee Osteoarthritis
Knee Injuries

Interventions: Other: Knee Joint Effusion

First Posted Date: 2019-01-15

Last Posted Date: 2025-02-21

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT03805464

Locations: 🇺🇸
Michael W. Krzyzewski Human Performance Laboratory, Durham, North Carolina, United States

Emotion Regulation and Emotion Perception

Not Applicable

Completed

Conditions: Emotions

Interventions: Behavioral: Habituation
Behavioral: Mindful Breathing
Behavioral: Control

First Posted Date: 2019-01-02

Last Posted Date: 2021-02-24

Lead Sponsor: Duke University

Target Recruit Count: 91

Registration Number: NCT03790878

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients

Phase 4

Completed

Conditions: Hyperkalemia
End Stage Renal Disease

Interventions: Drug: Patiromer Oral Powder Product

First Posted Date: 2018-12-19

Last Posted Date: 2025-05-30

Lead Sponsor: Duke University

Target Recruit Count: 36

Registration Number: NCT03781089

Locations: 🇺🇸
DaVita Dialysis Sites, Durham, North Carolina, United States

ED90 for Hyperbaric Bupivacaine in Super Obese Parturients

Phase 4

Completed

Conditions: Obesity, Morbid
Spinal Anesthesia
Cesarean Delivery

Interventions: Drug: Bupivacaine

First Posted Date: 2018-12-19

Last Posted Date: 2023-02-02

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT03781388

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

DeStress for Health: Partnering With Granville and Vance Counties to Reduce Stress and Cancer Risk

Not Applicable

Completed

Conditions: Stress Reduction

Interventions: Behavioral: DeStress for Health Program

First Posted Date: 2018-12-17

Last Posted Date: 2023-03-06

Lead Sponsor: Duke University

Target Recruit Count: 29

Registration Number: NCT03776890

Locations: 🇺🇸
Granville Vance Public Health Department, Oxford, North Carolina, United States

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