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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention

Phase 2

Completed

Conditions: Edema, Pulmonary
Immersion
Diving

Interventions: Drug: Placebo Oral Tablet
Drug: Sildenafil Citrate

First Posted Date: 2018-09-27

Last Posted Date: 2022-11-22

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT03686813

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Impact of Reduced Cannabis Use on Functional Outcomes

Not Applicable

Completed

Conditions: Cannabis
Cannabis Use

Interventions: Behavioral: Mobile Contingency Management, active

First Posted Date: 2018-09-24

Last Posted Date: 2021-03-05

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT03681353

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma

Not Applicable

Active, not recruiting

Conditions: Diffuse Large B Cell Lymphoma

Interventions: Radiation: Radiation Therapy

First Posted Date: 2018-09-24

Last Posted Date: 2025-03-11

Lead Sponsor: Duke University

Target Recruit Count: 241

Registration Number: NCT03681535

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Dana Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸
Dana-Farber/Brigham and Women's Cancer Center in clinical affiliation with South Shore Hospital, Weymouth, Massachusetts, United States

and more 9 locations

Mobile Health Case Management System for Reducing Pediatric Treatment Abandonment

Not Applicable

Completed

Conditions: Diffuse Large B-cell Lymphoma
Burkitt Lymphoma
Retinoblastoma

Interventions: Other: mNavigator

First Posted Date: 2018-09-19

Last Posted Date: 2023-05-09

Lead Sponsor: Duke University

Target Recruit Count: 75

Registration Number: NCT03677128

Locations: 🇹🇿
Bugando Medical Centre, Mwanza, Lake Zone, Tanzania

A Phase 2 Study of Home Care Following Autologous Hematopoietic Stem Cell Transplantation

Not Applicable

Recruiting

Conditions: Well-being of Caregivers (Caregiver Strain Index)

Interventions: Other: home care

First Posted Date: 2018-09-12

Last Posted Date: 2025-03-17

Lead Sponsor: Duke University

Target Recruit Count: 150

Registration Number: NCT03667599

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Evaluation of the iMBC/ECD Model in Ghana

Not Applicable

Completed

Conditions: Early Childhood Development

Interventions: Behavioral: Integrated Mothers and Babies Course

First Posted Date: 2018-09-11

Last Posted Date: 2020-07-24

Lead Sponsor: Duke University

Target Recruit Count: 378

Registration Number: NCT03665246

Locations: 🇬🇭
Catholic Relief Services, Tamale, Ghana

Communicating About Sexual Concerns and Dysfunction Effectively (CASCADE) Program

Not Applicable

Completed

Conditions: Cancer

Interventions: Behavioral: Communicating About Sexual Concerns and Dysfunction Effectively

First Posted Date: 2018-09-05

Last Posted Date: 2019-09-23

Lead Sponsor: Duke University

Target Recruit Count: 37

Registration Number: NCT03658161

Locations: 🇺🇸
Duke Cancer Institute, Durham, North Carolina, United States

Pain Perception During Vulvar Biopsy

Phase 4

Terminated

Conditions: Any Condition Requiring Vulvar Biopsy

Interventions: Drug: Lidocaine
Drug: EMLA

First Posted Date: 2018-08-31

Last Posted Date: 2020-01-18

Lead Sponsor: Duke University

Target Recruit Count: 37

Registration Number: NCT03654417

Locations: 🇺🇸
Duke Univeristy, Durham, North Carolina, United States

Implementation and Evaluations of Sepsis Watch

Not Applicable

Completed

Conditions: Severe Sepsis
Septic Shock
Sepsis

Interventions: Other: Sepsis Watch

First Posted Date: 2018-08-31

Last Posted Date: 2019-08-01

Lead Sponsor: Duke University

Target Recruit Count: 32003

Registration Number: NCT03655626

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Multi-Drug Resistant Organism Network

Completed

Conditions: Infections Resistant to Multiple Drugs
Bacterial Infections

First Posted Date: 2018-08-24

Last Posted Date: 2023-03-06

Lead Sponsor: Duke University

Target Recruit Count: 6496

Registration Number: NCT03646227

Locations: 🇨🇳
Huashan Hospital, Shanghai, Shanghai, China
🇨🇴
Universidad El Bosque, Bogota, Colombia
🇺🇸
Duke Clinical Research Institute, Durham, North Carolina, United States

and more 1 locations

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