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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075

Early Phase 1

Completed

Conditions: Opioid Use Disorder

Interventions: Drug: buprenorphine/naloxone
Other: Pharmacist-administered buprenorphine/naloxone maintenance care

First Posted Date: 2017-08-15

Last Posted Date: 2021-07-28

Lead Sponsor: Duke University

Target Recruit Count: 71

Registration Number: NCT03248947

Locations: 🇺🇸
Carolina Performance, Raleigh, North Carolina, United States
🇺🇸
Clinic Pharmacy, Durham, North Carolina, United States
🇺🇸
Duke Outpatient Clinic, Durham, North Carolina, United States

and more 3 locations

Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve

Phase 4

Terminated

Conditions: Hypertrophic Cardiomyopathy
Microvascular Ischaemia of Myocardium
Non-ischemic Dilated Cardiomyopathy

Interventions: Drug: Regadenoson
Drug: Adenosine

First Posted Date: 2017-08-15

Last Posted Date: 2020-09-16

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT03249272

Locations: 🇺🇸
Duke Cardiovascular Magnetic Resonance Center, Durham, North Carolina, United States

Patient Performed Examination for Patients With Intra-articular Hip Pain

Not Applicable

Completed

Conditions: Hip Pain Chronic
Hip Disease

Interventions: Other: Clinician-Performed Diagnostic Exam
Other: Patient Self-Administered Diagnostic Exam

First Posted Date: 2017-08-15

Last Posted Date: 2019-12-17

Lead Sponsor: Duke University

Target Recruit Count: 80

Registration Number: NCT03248934

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Active Recreation Through Community-Healthcare Engagement Study

Not Applicable

Completed

Conditions: Childhood Obesity
Quality of Life

Interventions: Behavioral: Integrated community-healthcare childhood obesity treatment

First Posted Date: 2017-08-11

Last Posted Date: 2020-08-14

Lead Sponsor: Duke University

Target Recruit Count: 202

Registration Number: NCT03246763

Locations: 🇺🇸
Wake Med, Raleigh, North Carolina, United States
🇺🇸
First Health, Biscoe, North Carolina, United States
🇺🇸
East Durham Children's Initiative, Durham, North Carolina, United States

and more 4 locations

Prevention of Urinary Stones With Hydration

Not Applicable

Completed

Conditions: Urinary Stones

Interventions: Behavioral: Fluid prescription
Behavioral: Financial incentive
Behavioral: Structured Problem Solving

First Posted Date: 2017-08-09

Last Posted Date: 2024-06-06

Lead Sponsor: Duke University

Target Recruit Count: 1658

Registration Number: NCT03244189

Locations: 🇺🇸
University of Washington, Seattle, Washington, United States
🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

and more 5 locations

Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings

Not Applicable

Completed

Conditions: Post Traumatic Stress Disorder
Depression
Grief

Interventions: Behavioral: Trauma-Focused Cognitive Behavioral Therapy

First Posted Date: 2017-08-09

Last Posted Date: 2025-04-01

Lead Sponsor: Duke University

Target Recruit Count: 956

Registration Number: NCT03243396

Locations: 🇰🇪
ACE Africa, Bungoma, Bungoma County, Kenya

BRS and Outcomes in Cardiothoracic Surgery

Completed

Conditions: Atrial Fibrillation
Cognitive Dysfunction
Pain, Postoperative

First Posted Date: 2017-08-08

Last Posted Date: 2022-07-21

Lead Sponsor: Duke University

Target Recruit Count: 72

Registration Number: NCT03243279

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Impact of Combined Medication and Behavioral Treatment for ASD & ADHD

Phase 2

Terminated

Conditions: Autism Spectrum Disorder
Attention Deficit Hyperactivity Disorder

Interventions: Drug: Amphetamine
Drug: Placebo Oral Tablet
Behavioral: ESDM informed parent coaching

First Posted Date: 2017-08-08

Last Posted Date: 2022-03-22

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT03242772

Locations: 🇺🇸
Duke Center for Autism and Brain Development, Durham, North Carolina, United States

Neurofeedback With Real-Time fMRI for Treatment of PTSD

Not Applicable

Withdrawn

Conditions: PTSD

Interventions: Device: fMRI - GE Medical System

First Posted Date: 2017-08-08

Last Posted Date: 2022-12-21

Lead Sponsor: Duke University

Registration Number: NCT03243149

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Retinal Imaging in Neurodegenerative Disease

Recruiting

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Neuro-Degenerative Disease
Normal Cognition
Post-Traumatic Stress Disorder
Alzheimer's Disease
Parkinson's Disease
Multiple Sclerosis
Huntington Disease
Concussion
Down Syndrome

Interventions: Device: Retinal and Choroidal Imaging

First Posted Date: 2017-07-28

Last Posted Date: 2025-01-27

Lead Sponsor: Duke University

Target Recruit Count: 2000

Registration Number: NCT03233646

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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