JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Retisert and Cataract Surgery in Patients With Severe Uveitis

Not Applicable

Completed

Conditions: Intermediate Uveitis
Posterior Uveitis

Interventions: Device: Retisert (fluocinolone acetonide implant)

First Posted Date: 2007-12-11

Last Posted Date: 2014-09-03

Lead Sponsor: Duke University

Target Recruit Count: 21

Registration Number: NCT00570830

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Feasibility of Cocooning Immunization Strategy With Influenza Vaccine

Not Applicable

Completed

Conditions: Influenza

Interventions: Biological: Trivalent inactivated influenza vaccine

First Posted Date: 2007-12-10

Last Posted Date: 2013-06-24

Lead Sponsor: Duke University

Target Recruit Count: 544

Registration Number: NCT00570037

Locations: 🇺🇸
Durham Regional Hospital, Durham, North Carolina, United States
🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis

Not Applicable

Terminated

Conditions: Aortic Stenosis

Interventions: Other: NT-pro-BNP levels

First Posted Date: 2007-12-05

Last Posted Date: 2012-10-24

Lead Sponsor: Duke University

Target Recruit Count: 110

Registration Number: NCT00567437

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg

Phase 1

Completed

Conditions: Melanoma (Skin)

Interventions: Drug: melphalan
Drug: sorafenib tosylate
Genetic: gene expression analysis
Genetic: protein expression analysis
Genetic: western blotting
Other: pharmacological study

First Posted Date: 2007-11-30

Last Posted Date: 2015-03-06

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT00565968

Locations: 🇺🇸
Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Phase II Study Evaluating The Safety And Response To Neoadjuvant Dasatinib In Early Stage Non-Small Cell Lung Cancer

Phase 2

Terminated

Conditions: Carcinoma, Non-Small-Cell Lung

Interventions: Drug: Dasatinib

First Posted Date: 2007-11-28

Last Posted Date: 2015-02-23

Lead Sponsor: Duke University

Target Recruit Count: 2

Registration Number: NCT00564876

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

KAN-DO: A Family-based Intervention to Prevent Childhood Obesity

Not Applicable

Completed

Conditions: Obesity
Postpartum Period
Prevention & Control

Interventions: Behavioral: KAN-DO

First Posted Date: 2007-11-26

Last Posted Date: 2014-07-11

Lead Sponsor: Duke University

Target Recruit Count: 832

Registration Number: NCT00563264

Locations: 🇺🇸
Duke University Dept. of Community and Family Medicine, Durham, North Carolina, United States
🇺🇸
UNC Greensboro, Greensboro, North Carolina, United States

Phase II Dasatinib Study in Advanced Breast Cancer

Phase 2

Completed

Conditions: Advanced Breast Cancer

Interventions: Drug: Dasatinib

First Posted Date: 2007-10-18

Last Posted Date: 2013-07-17

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT00546104

Locations: 🇺🇸
Palm Beach Cancer Center Institute, West Palm Beach, Florida, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Presbyterian Health Care, Charlotte, North Carolina, United States

Adjuvant Cisplatin With Either Genomic-Guided Vinorelbine or Pemetrexed for Early Stage Non-Small-Cell Lung Cancer

Phase 2

Terminated

Conditions: Carcinoma, Non-Small-Cell Lung

Interventions: Drug: Vinorelbine followed by Cisplatin
Drug: Pemetrexed followed by Cisplatin

First Posted Date: 2007-10-18

Last Posted Date: 2014-07-21

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT00545948

Locations: 🇺🇸
Palm Beach Cancer Institute, West Palm Beach, Florida, United States
🇺🇸
Maria Parham Hospital, Henderson, North Carolina, United States
🇺🇸
Presbyterian HealthCare, Charlotte, North Carolina, United States

and more 10 locations

Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment

Phase 4

Completed

Conditions: Uveitis

Interventions: Drug: 0.59 mg Fluocinolone Acetonide implant

First Posted Date: 2007-10-12

Last Posted Date: 2015-03-31

Lead Sponsor: Duke University

Target Recruit Count: 21

Registration Number: NCT00543296

Locations: 🇺🇸
Duke University Eye Center, Durham, North Carolina, United States

Behavioral Insomnia Therapy With Chronic Fatigue Syndrome

Phase 1

Completed

Conditions: Chronic Fatigue Syndrome
Behavioral Therapy Targeted to Sleep Problems

Interventions: Behavioral: Cognitive Behavioral Therapy
Other: Usual Care for Chronic Fatigue Syndrome (Active Control Group)

First Posted Date: 2007-10-05

Last Posted Date: 2013-03-01

Lead Sponsor: Duke University

Target Recruit Count: 24

Registration Number: NCT00540254

Locations: 🇺🇸
Duke University Medical Center - Insomnia and Sleep Disorders Lab, Durham, North Carolina, United States

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