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JOHN HOPE FRANKLIN CENTER

JOHN HOPE FRANKLIN CENTER logo
🇺🇸United States
Ownership
Private
Established
1838-01-01
Employees
5K
Market Cap
-
Website
http://www.duke.edu

Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy

Phase 1
Recruiting
Conditions
Hepatic Encephalopathy
Interventions
Drug: PPI deprescribing
First Posted Date
2021-10-07
Last Posted Date
2024-03-06
Lead Sponsor
Duke University
Target Recruit Count
40
Registration Number
NCT05070351
Locations
🇺🇸

Duke University Hospital, Durham, North Carolina, United States

Comparing Effectiveness of CSE Versus DPE for Labor Analgesia

Phase 4
Completed
Conditions
Labor Pain
Interventions
Drug: Ropivacaine 0.1% Injectable Solution
Drug: Bupivacaine 0.25% Injectable Solution
First Posted Date
2021-10-06
Last Posted Date
2024-11-06
Lead Sponsor
Duke University
Target Recruit Count
101
Registration Number
NCT05068661
Locations
🇺🇸

Duke University Hospital, Durham, North Carolina, United States

Learning Health for Pediatric Complex Care Integration (PCCI)

Completed
Conditions
Children and Youth With Special Healthcare Needs
Care Coordination
Interventions
Other: Surveys
First Posted Date
2021-09-24
Last Posted Date
2022-10-13
Lead Sponsor
Duke University
Target Recruit Count
20
Registration Number
NCT05056480
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Recruiting
Conditions
Critically Ill
Children, Adult
Cardiac Disease
Interventions
Drug: The OPTIC study is collecting PK data on children prescribed understudied drugs of interest per standard of care.
First Posted Date
2021-09-24
Last Posted Date
2024-10-09
Lead Sponsor
Duke University
Target Recruit Count
2000
Registration Number
NCT05055830
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Caremap: A Digital Personal Health Record for Complex Care Coordination

Not Applicable
Completed
Conditions
Adults With Multiple Chronic Conditions
Children/Youth With Special Healthcare Needs
Interventions
Other: Caremap app
First Posted Date
2021-09-24
Last Posted Date
2024-11-21
Lead Sponsor
Duke University
Target Recruit Count
17
Registration Number
NCT05056493
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

Test to Stay in School: COVID-19 Testing Following Exposure in School Communities

Not Applicable
Completed
Conditions
Covid19
Interventions
Other: COVID-19 Testing
First Posted Date
2021-09-22
Last Posted Date
2023-11-27
Lead Sponsor
Duke University
Target Recruit Count
4733
Registration Number
NCT05052580
Locations
🇺🇸

Participating NC School Districts, Durham, North Carolina, United States

Effect of Corticosteroid Injections on Blood Glucose

Suspended
Conditions
Diabetes Mellitus
Steroid Diabetes
Knee Osteoarthritis
Hip Osteoarthritis
Shoulder Osteoarthritis
Adhesive Capsulitis
First Posted Date
2021-09-17
Last Posted Date
2024-11-15
Lead Sponsor
Duke University
Target Recruit Count
55
Registration Number
NCT05048264
Locations
🇺🇸

Duke Sports Science Institute, Durham, North Carolina, United States

The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study

Not Applicable
Withdrawn
Conditions
Choroideremia
Interventions
Dietary Supplement: Vitamin A palmitate
First Posted Date
2021-09-16
Last Posted Date
2023-06-29
Lead Sponsor
Duke University
Registration Number
NCT05045703
Locations
🇺🇸

Duke Eye Center, Durham, North Carolina, United States

Low Nicotine Cigarettes, Smoking, and Chronic Pain

Not Applicable
Active, not recruiting
Conditions
Chronic Pain
Smoking, Cigarette
Interventions
Other: SPECTRUM NRC 600/601 investigational cigarettes
Other: SPECTRUM NRC 102/103 investigational cigarettes
First Posted Date
2021-09-02
Last Posted Date
2024-06-27
Lead Sponsor
Duke University
Target Recruit Count
36
Registration Number
NCT05032755
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Efficacy Testing of a Culturally Relevant Stigma Intervention With WLWH in Tanzania

Not Applicable
Completed
Conditions
Self Esteem
Hope
Self Efficacy
Depressive Symptoms
HIV
Stigma, Social
Interventions
Behavioral: Labda Siku Moja stigma reduction intervention
First Posted Date
2021-09-02
Last Posted Date
2024-10-23
Lead Sponsor
Duke University
Target Recruit Count
167
Registration Number
NCT05033002
Locations
🇹🇿

Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania

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