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JOHN HOPE FRANKLIN CENTER

JOHN HOPE FRANKLIN CENTER logo
🇺🇸United States
Ownership
Private
Established
1838-01-01
Employees
5K
Market Cap
-
Website
http://www.duke.edu

PROSPective Evaluation of Fortified Eggs Related to Improvement in The Biomarker Profile for Your Health

Not Applicable
Completed
Conditions
Hypercholesterolemia
Hyperlipidemia
Vitamin Deficiency
Obesity
Interventions
Behavioral: Intermittent fasting
Dietary Supplement: Fortified eggs
Dietary Supplement: Non-egg supplemented
Behavioral: Usual care diet
First Posted Date
2020-12-17
Last Posted Date
2023-01-23
Lead Sponsor
Duke University
Target Recruit Count
140
Registration Number
NCT04673721
Locations
🇺🇸

Duke University Health System, Durham, North Carolina, United States

Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx

Not Applicable
Recruiting
Conditions
Oropharynx Cancer
Interventions
Radiation: De-escalated radiation dose
Radiation: Standard radiation dose
Other: 18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)-Computed Tomography (CT)
First Posted Date
2020-12-14
Last Posted Date
2024-06-21
Lead Sponsor
Duke University
Target Recruit Count
120
Registration Number
NCT04667585
Locations
🇺🇸

Duke Raleigh Hospital, Raleigh, North Carolina, United States

🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)

Not Applicable
Completed
Conditions
Covid19
Critical Illness
Intensive Care Units
Fitness Trackers
ICU
High Intensity Interval Training
Interventions
Behavioral: REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT)
Other: Comparator
First Posted Date
2020-12-11
Last Posted Date
2024-01-18
Lead Sponsor
Duke University
Target Recruit Count
13
Registration Number
NCT04664101
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

🇺🇸

Vanderbilt University, Nashville, Tennessee, United States

Piloting a Smartphone App to Improve Treatment Adherence Among South African Adolescents Living With HIV

Not Applicable
Completed
Conditions
Adolescent Behavior
HIV Infections
Interventions
Behavioral: Informational Resources
Behavioral: Social Support
Behavioral: Self-Monitoring and habit formation
Behavioral: Goal setting and action planning
First Posted Date
2020-12-10
Last Posted Date
2024-04-18
Lead Sponsor
Duke University
Target Recruit Count
50
Registration Number
NCT04661878
Locations
🇿🇦

University of Cape Town, Cape Town, South Africa

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

Not Applicable
Conditions
Cardiac Arrest
Interventions
Other: Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators
Other: Systematic bystander resuscitation instruction by 911 operators
Other: Comprehensive community training of lay people in CPR and AED use.
Other: Optimized first responder performance including earlier use of AEDs.
First Posted Date
2020-12-09
Last Posted Date
2024-04-23
Lead Sponsor
Duke University
Target Recruit Count
20000
Registration Number
NCT04660526
Locations
🇺🇸

Duke, Durham, North Carolina, United States

Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma

Recruiting
Conditions
Glioblastoma
Interventions
Other: Biorepository
First Posted Date
2020-12-08
Last Posted Date
2024-10-10
Lead Sponsor
Duke University
Target Recruit Count
40
Registration Number
NCT04657146
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

A Pilot Study of a Micro-Organosphere Drug Screen Platform to Lead Care in Advanced Breast Cancer

Terminated
Conditions
Advanced Breast Cancer
Interventions
Procedure: Breast Cancer Tumor Resection
First Posted Date
2020-12-07
Last Posted Date
2024-05-16
Lead Sponsor
Duke University
Target Recruit Count
7
Registration Number
NCT04655573
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer

Phase 2
Withdrawn
Conditions
Non Small Cell Lung Cancer
Brain Metastases
Interventions
Radiation: Stereotactic Radiosurgery
Drug: Immunotherapy
First Posted Date
2020-12-02
Last Posted Date
2023-03-02
Lead Sponsor
Duke University
Registration Number
NCT04650490
Locations
🇺🇸

Duke Cancer Center, Durham, North Carolina, United States

AirFLO2 Treatment for Hypoxia and/or Tachypnea in Patients With COVID-19

Not Applicable
Terminated
Conditions
Corona Virus Infection
Hypoxia
Covid19
Respiratory Rate
Interventions
Device: AirFLO2
First Posted Date
2020-12-02
Last Posted Date
2022-11-25
Lead Sponsor
Duke University
Target Recruit Count
11
Registration Number
NCT04649775
Locations
🇺🇸

Duke University Health System, Durham, North Carolina, United States

Reliability and Reproducibility of the Eye Check Tonometer

Not Applicable
Terminated
Conditions
Glaucoma
Glaucoma, Suspect
Interventions
Device: Traditional Tonometer (Goldmann and Tonopen)
Device: EyeCheck
First Posted Date
2020-11-23
Last Posted Date
2024-10-08
Lead Sponsor
Duke University
Target Recruit Count
22
Registration Number
NCT04639947
Locations
🇺🇸

Duke Eye Center, Durham, North Carolina, United States

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