JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

A Text-based Reduction Intervention for Smokeless Tobacco Cessation

Not Applicable

Completed

Conditions: Smokeless Tobacco Cessation

Interventions: Behavioral: #EnufSnuff.TXT Intervention
Behavioral: Enough Snuff Intervention

First Posted Date: 2020-03-19

Last Posted Date: 2024-07-17

Lead Sponsor: Duke University

Target Recruit Count: 532

Registration Number: NCT04315506

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Perioperative Tissue Penetration of Antimicrobials in Infants

Completed

Conditions: Bowel Dysfunction

Interventions: Procedure: Bowel Surgery with Metronidazole

First Posted Date: 2020-03-09

Last Posted Date: 2022-07-28

Lead Sponsor: Duke University

Target Recruit Count: 23

Registration Number: NCT04299867

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Quality Improvement Project for Advance Care Planning Tool in Hospital Medicine

Completed

Conditions: Advance Care Planning

Interventions: Other: Advance Care Planning Discussion

First Posted Date: 2020-03-05

Last Posted Date: 2022-05-18

Lead Sponsor: Duke University

Target Recruit Count: 743

Registration Number: NCT04296136

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder

Phase 1

Completed

Conditions: Autism Spectrum Disorder

Interventions: Biological: hCT-MSC infusion

First Posted Date: 2020-03-04

Last Posted Date: 2023-01-20

Lead Sponsor: Duke University

Target Recruit Count: 12

Registration Number: NCT04294290

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Emergency Department Acupuncture for Acute Musculoskeletal Pain Management

Not Applicable

Completed

Conditions: Musculoskeletal Pain

Interventions: Procedure: Auricular (Battlefield) Acupuncture
Procedure: Peripheral Acupuncture

First Posted Date: 2020-03-02

Last Posted Date: 2023-07-06

Lead Sponsor: Duke University

Target Recruit Count: 599

Registration Number: NCT04290741

Locations: 🇺🇸
Duke University Hospital Emergency Department, Durham, North Carolina, United States

Nitrite Infusion in Children With Malaria

Phase 1

Withdrawn

Conditions: Falciparum Malaria

Interventions: Drug: Sodium Nitrite

First Posted Date: 2020-02-28

Last Posted Date: 2021-03-16

Lead Sponsor: Duke University

Registration Number: NCT04289558

Locations: 🇹🇿
Hubert Kairuki Memorial University, Dar es Salaam, Tanzania

Skeletal Muscle Health in Children With Type 1 Diabetes

Completed

Conditions: Type 1 Diabetes

First Posted Date: 2020-02-27

Last Posted Date: 2023-12-11

Lead Sponsor: Duke University

Target Recruit Count: 29

Registration Number: NCT04288063

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Arterial Versus Venous Activated Clotting Time (ACT) Measurements During Atrial Fibrillation Ablations

Not Applicable

Completed

Conditions: Atrial Fibrillation

Interventions: Other: Venous ACT

First Posted Date: 2020-02-26

Last Posted Date: 2021-06-28

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT04285840

Locations: 🇺🇸
Duke Health Raleigh, Raleigh, North Carolina, United States

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Recruiting

Conditions: Pulmonary Arterial Hypertension
Urinary Tract Infections in Children
Hemophilia
Menorrhagia
Attention Deficit Hyperactivity Disorder
Multisystem Inflammatory Syndrome in Children (MIS-C)
Coronavirus Infection (COVID-19)
Pain
Hyperphosphatemia
Edema

First Posted Date: 2020-02-20

Last Posted Date: 2024-06-28

Lead Sponsor: Duke University

Target Recruit Count: 5000

Registration Number: NCT04278404

Locations: 🇺🇸
University of South Carolina, Columbia, South Carolina, United States
🇺🇸
University of Texas-Southwestern Medical Center Dallas, Dallas, Texas, United States
🇺🇸
The Womens Hospital of Texas, Houston, Texas, United States

and more 46 locations

System for High-Intensity Evaluation During Radiotherapy

Not Applicable

Completed

Conditions: Chemotherapeutic Toxicity
Radiation Therapy Complication

Interventions: Other: Machine learning algorithm

First Posted Date: 2020-02-20

Last Posted Date: 2021-05-19

Lead Sponsor: Duke University

Target Recruit Count: 311

Registration Number: NCT04277650

Locations: 🇺🇸
Duke Cancer Center, Durham, North Carolina, United States

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