JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Trial of Rifaximin in Probable Alzheimer's Disease

Phase 2

Completed

Conditions: Alzheimer's Disease

Interventions: Drug: Rifaximin 550 milligrams (MG)

First Posted Date: 2019-02-27

Last Posted Date: 2021-12-17

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT03856359

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

Phase 2

Completed

Conditions: Vestibulodynia
Temporomandibular Disorder
Migraines
Tension Headache
Fibromyalgia Syndrome
Interstitial Cystitis
Chronic Fatigue Syndrome
Back Pain
Irritable Bowel Syndrome
Endometriosis

Interventions: Drug: 5% lidocaine/5 mg/ml 0.02% estradiol compound cream
Drug: Nortriptyline
Drug: Placebo pill
Drug: Placebo cream

First Posted Date: 2019-02-18

Last Posted Date: 2024-06-07

Lead Sponsor: Duke University

Target Recruit Count: 223

Registration Number: NCT03844412

Locations: 🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
🇺🇸
University of California, Los Angeles, Los Angeles, California, United States

Harnessing Sleep/Circadian Rhythm Data as a Biomarker to Mitigate Health Risks

Completed

Conditions: Adolescent Behavior

First Posted Date: 2019-02-18

Last Posted Date: 2020-04-27

Lead Sponsor: Duke University

Target Recruit Count: 106

Registration Number: NCT03843762

Locations: 🇺🇸
Duke Child and Family Study Center, Durham, North Carolina, United States

Healthy Me: A Program for Older Women

Not Applicable

Active, not recruiting

Conditions: Obesity

Interventions: Behavioral: Take of Pounds Sensibly (TOPS)
Other: Waitlist Control

First Posted Date: 2019-02-18

Last Posted Date: 2024-08-19

Lead Sponsor: Duke University

Target Recruit Count: 115

Registration Number: NCT03843190

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-world Behavior

Not Applicable

Terminated

Conditions: Nicotine Withdrawal
Cigarette Smoking

Interventions: Other: Smoking Abstinence
Other: Ad Lib Smoking

First Posted Date: 2019-02-15

Last Posted Date: 2021-05-20

Lead Sponsor: Duke University

Target Recruit Count: 21

Registration Number: NCT03840694

Locations: 🇺🇸
Duke University School of Medicine, Durham, North Carolina, United States

Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA)

Phase 3

Active, not recruiting

Conditions: Juvenile Idiopathic Arthritis

Interventions: Drug: Abatacept Injection
Other: Usual Care

First Posted Date: 2019-02-15

Last Posted Date: 2024-01-18

Lead Sponsor: Duke University

Target Recruit Count: 121

Registration Number: NCT03841357

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, United States
🇺🇸
Seattle Children's Hospital, Seattle, Washington, United States

and more 16 locations

Case Managers for CVD Risk Reduction in HIV Clinic

Not Applicable

Completed

Conditions: Cardiovascular Disease
HIV

Interventions: Behavioral: Telephone
Other: Educational pamphlets

First Posted Date: 2019-02-15

Last Posted Date: 2023-12-05

Lead Sponsor: Duke University

Target Recruit Count: 50

Registration Number: NCT03839394

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Collecting Outcomes and Managing Pain After Surgery

Not Applicable

Not yet recruiting

Conditions: Surgery

Interventions: Behavioral: COMPAS Participants

First Posted Date: 2019-02-08

Last Posted Date: 2024-06-27

Lead Sponsor: Duke University

Target Recruit Count: 10000

Registration Number: NCT03834818

Locations: 🇺🇸
Duke Orthopaedics, Durham, North Carolina, United States

QL Block With Exparel in Colectomy

Phase 4

Completed

Conditions: Colectomy
Laparotomy

Interventions: Other: Thoracic epidural analgesia
Drug: Exparel

First Posted Date: 2019-02-01

Last Posted Date: 2022-12-20

Lead Sponsor: Duke University

Target Recruit Count: 42

Registration Number: NCT03827291

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

Phase 2

Completed

Conditions: Stroke, Ischemic
Motor Activity
Upper Extremity Paralysis

Interventions: Device: High dose tDCS
Device: Low dose tDCS
Device: Sham
Behavioral: mCIMT

First Posted Date: 2019-02-01

Last Posted Date: 2024-12-27

Lead Sponsor: Duke University

Target Recruit Count: 129

Registration Number: NCT03826030

Locations: 🇺🇸
Burke Rehabilitation Center, White Plains, New York, United States
🇺🇸
University of Alabama at Birmingham Hospital, Birmingham, Alabama, United States
🇺🇸
Keck Hospital of USC, Los Angeles, California, United States

and more 11 locations

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