JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Effect of Prebiotic Fiber- Enriched (scFOS) Enteral Feeding on the Microbiome in Neurological Injury Trauma Patients (PreFEED Microbiome Trial)

Not Applicable

Completed

Conditions: Brain Injuries, Traumatic
ICU Admission
Enteral Nutrition

Interventions: Other: Osmolite
Other: Nutraflora scFOS

First Posted Date: 2017-05-15

Last Posted Date: 2021-06-04

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT03153397

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Teaching Improved Communication To Adolescents and Clinicians

Not Applicable

Completed

Conditions: Communication Improvement Between Adolescent and Clinician

Interventions: Behavioral: Communication Intervention

First Posted Date: 2017-05-12

Last Posted Date: 2018-12-11

Lead Sponsor: Duke University

Target Recruit Count: 36

Registration Number: NCT03152045

Locations: 🇺🇸
Duke University Medical Center - Cancer Prevention, Detection and Control, Durham, North Carolina, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Changing the Pulse of Athletics: Applying a Standardized Cardiac Athletic Screening for NCAA Athletes

Completed

Conditions: Athletes Heart

Interventions: Diagnostic Test: ECG
Diagnostic Test: bedside cardiac ultrasound

First Posted Date: 2017-05-12

Last Posted Date: 2017-11-17

Lead Sponsor: Duke University

Target Recruit Count: 42

Registration Number: NCT03150940

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study

Phase 4

Recruiting

Conditions: Sarcoma
Hyperbaric Oxygen Therapy

Interventions: Drug: Hyperbaric oxygen

First Posted Date: 2017-05-08

Last Posted Date: 2024-06-05

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT03144206

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Pediatric Obesity Observational Prospective Trial

Completed

Conditions: Pediatric Obesity

First Posted Date: 2017-05-04

Last Posted Date: 2021-06-18

Lead Sponsor: Duke University

Target Recruit Count: 295

Registration Number: NCT03139877

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

A Wearable EducAtional Intervention to REduce Angina

Not Applicable

Withdrawn

Conditions: Angina

Interventions: Other: End-of-Study Feedback
Other: Monthly Feedback on activity and patient-reported angina

First Posted Date: 2017-04-28

Last Posted Date: 2017-08-21

Lead Sponsor: Duke University

Registration Number: NCT03134105

Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers

Terminated

Conditions: Kidney Cancer
Prostate Cancer
Genito Urinary Cancer
Bladder Cancer

Interventions: Procedure: Bone marrow biopsy
Procedure: Tumor biopsy

First Posted Date: 2017-04-28

Last Posted Date: 2024-07-18

Lead Sponsor: Duke University

Target Recruit Count: 3

Registration Number: NCT03134027

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Locally Advanced NSCLC Hyperfractionated RT

Phase 2

Completed

Conditions: Carcinoma, Non Small Cell Lung (NSCLC)

Interventions: Drug: Carboplatin
Drug: Paclitaxel
Radiation: Daily hyperfractionated radiation therapy

First Posted Date: 2017-04-25

Last Posted Date: 2021-05-28

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT03128008

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Effect of Bupropion on Seizure Threshold in Depressed Patients

Phase 4

Completed

Conditions: MDD

Interventions: Drug: Wellbutrin SR 300Mg Extended-Release Tablet

First Posted Date: 2017-04-24

Last Posted Date: 2019-07-10

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT03126682

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Contributing Factors in the Pathobiology of Airway Remodeling in Obesity

Completed

Conditions: Obesity, Morbid
Asthma
Bariatric Surgery Candidate
Obesity

First Posted Date: 2017-04-14

Last Posted Date: 2023-09-22

Lead Sponsor: Duke University

Target Recruit Count: 31

Registration Number: NCT03115632

Locations: 🇺🇸
Duke Asthma Allergy and Airway Center, Durham, North Carolina, United States
🇺🇸
Duke Metabolic and Weight Loss Surgery Center, Durham, North Carolina, United States

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