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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy

Phase 2
Active, not recruiting
Conditions
Hepatitis B, Chronic
Interventions
Biological: GSK3528869A
Drug: Control
First Posted Date
2022-03-11
Last Posted Date
2025-04-04
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
174
Registration Number
NCT05276297
Locations
🇬🇧

GSK Investigational Site, Leicester, United Kingdom

Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps

Phase 3
Completed
Conditions
Nasal Polyps
Interventions
Biological: Depemokimab (GSK3511294)
Drug: Placebo
First Posted Date
2022-03-10
Last Posted Date
2025-03-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
276
Registration Number
NCT05274750
Locations
🇬🇧

GSK Investigational Site, Wigan, United Kingdom

A Study to Evaluate Pharmacokinetic, Safety, Tolerability and Relative Bioavailability of Gepotidacin in Healthy Adult Male and Female Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2022-03-09
Last Posted Date
2023-01-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
24
Registration Number
NCT05271799
Locations
🇺🇸

GSK Investigational Site, Las Vegas, Nevada, United States

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)

Phase 3
Recruiting
Conditions
Eosinophilic Granulomatosis With Polyangiitis
Interventions
First Posted Date
2022-03-03
Last Posted Date
2025-05-23
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
160
Registration Number
NCT05263934
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants

Phase 1
Completed
Conditions
COVID-19
SARS-CoV-2
Interventions
Biological: CV2CoV (2 µg)
Biological: CV2CoV (8 µg)
Biological: CV2CoV (20 µg)
Biological: CV2CoV (4 µg)
Biological: CV2CoV (12 µg)
Biological: CV2CoV (16 µg)
First Posted Date
2022-03-02
Last Posted Date
2024-08-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
99
Registration Number
NCT05260437
Locations
🇺🇸

GSK Investigational Site, West Jordan, Utah, United States

🇺🇸

Accel Research Sites, Lakeland, Florida, United States

🇺🇸

MD Clinical - Velocity, Hallandale Beach, Florida, United States

and more 9 locations

An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)

Phase 3
Active, not recruiting
Conditions
Asthma
Interventions
Biological: GSK3511294 (Depemokimab)
First Posted Date
2022-02-17
Last Posted Date
2025-03-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
641
Registration Number
NCT05243680
Locations
🇬🇧

GSK Investigational Site, Nottingham, United Kingdom

A Study of Safety, Reactogenicity and Immune Response of the Repeat Vaccination Against RSV When Given to Female Participants of 18-49 Years of Age During Their Subsequent Uncomplicated Pregnancy

Phase 3
Withdrawn
Conditions
Respiratory Syncytial Virus Infections
Interventions
Biological: RSV MAT
First Posted Date
2022-02-08
Last Posted Date
2022-04-07
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT05229068
Locations
🇺🇸

GSK Investigational Site, Norfolk, Nebraska, United States

A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India

Phase 3
Completed
Conditions
Herpes Zoster
Interventions
Drug: Placebo
First Posted Date
2022-02-02
Last Posted Date
2025-05-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
288
Registration Number
NCT05219253
Locations
🇮🇳

GSK Investigational Site, Pune, India

Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK3858279 in Healthy Caucasian, Chinese and Japanese Participants

Phase 1
Completed
Conditions
Pain
Interventions
Drug: Placebo
First Posted Date
2021-12-30
Last Posted Date
2025-05-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
33
Registration Number
NCT05174013
Locations
🇦🇺

GSK Investigational Site, Melbourne, Victoria, Australia

A Study to Evaluate the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine in Healthy Non-pregnant Females From 9 to 49 Years of Age

Phase 3
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Combination Product: RSV MAT vaccine
Combination Product: dTpa vaccine
First Posted Date
2021-12-27
Last Posted Date
2023-04-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
9
Registration Number
NCT05169905
Locations
🇺🇸

GSK Investigational Site, Beaumont, Texas, United States

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