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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Mechanistic Study of GSK3196165 Plus Methotrexate (MTX) in Subjects With Active Rheumatoid Arthritis

Phase 2
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Placebo
Drug: Folic (or folinic) acid
First Posted Date
2016-06-14
Last Posted Date
2021-01-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
39
Registration Number
NCT02799472
Locations
🇵🇱

GSK Investigational Site, Wroclaw, Poland

A Study to Evaluate Persistence of Hepatitis B Antibodies, Immunogenicity and Safety of Engerix™-B Kinder Challenge Dose, in Adolescents Vaccinated With Four Doses of Infanrix™ Hexa During Infancy

Phase 4
Completed
Conditions
Hepatitis B
Interventions
Biological: Engerix-B Kinder
First Posted Date
2016-06-14
Last Posted Date
2020-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
302
Registration Number
NCT02798952
Locations
🇩🇪

GSK Investigational Site, Neumuenster, Germany

A Phase I, 2-part (Part 1 Being a Single Dose Escalation and Part 2, a Parallel Group) Study of Toll-like Receptor (TLR4) Agonist (GSK1795091) in Healthy Subjects

Phase 1
Completed
Conditions
Neoplasms
Cancer
Interventions
Drug: Placebo
First Posted Date
2016-06-14
Last Posted Date
2020-11-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
42
Registration Number
NCT02798978
Locations
🇩🇪

GSK Investigational Site, Berlin, Germany

A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects

Phase 1
Completed
Conditions
Irritable Bowel Syndrome
Interventions
Drug: Matched Placebo
First Posted Date
2016-06-14
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
46
Registration Number
NCT02798991
Locations
🇦🇺

GSK Investigational Site, Adelaide, South Australia, Australia

Single and Repeated Dose Escalation Study of GSK2838232

Phase 1
Completed
Conditions
Infection, Human Immunodeficiency Virus
Interventions
Drug: GSK2838232 PIB
Drug: GSK2838232 IR1
Drug: Placebo PIB
Drug: GSK2838232 IR2
First Posted Date
2016-06-10
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
62
Registration Number
NCT02795754
Locations
🇺🇸

GSK Investigational Site, Baltimore, Maryland, United States

A Phase 2a Study to Evaluate the Effects of Sirukumab in Subjects With Severe Poorly Controlled Asthma

Phase 2
Withdrawn
Conditions
Asthma
Interventions
Drug: Placebo
Drug: Rescue medication
First Posted Date
2016-06-09
Last Posted Date
2018-08-31
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT02794519
Locations
🇪🇸

GSK Investigational Site, Santiago De Compostela. La Coruña., Spain

Placebo-controlled Proof of Concept Study of Epelsiban in Women With Adenomyosis

Phase 2
Withdrawn
Conditions
Adenomyosis
Interventions
Drug: Placebo
First Posted Date
2016-06-09
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT02794467
Locations
🇺🇸

GSK Investigational Site, Houston, Texas, United States

Phase IV Study in Asthma Subjects for Dry Powder Inhaler (DPI) Versus (vs) Metered Dose Inhaler (MDI) Correct Use

Phase 4
Completed
Conditions
Asthma
Interventions
Device: ELLIPTA DPI
Device: GSK MDI
Device: AZ MDI
First Posted Date
2016-06-09
Last Posted Date
2019-07-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
324
Registration Number
NCT02794480
Locations
🇺🇸

GSK Investigational Site, Waco, Texas, United States

An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects

Phase 4
Terminated
Conditions
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2016-06-08
Last Posted Date
2020-10-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
4
Registration Number
NCT02793154
Locations
🇺🇸

GSK Investigational Site, Dallas, Texas, United States

Phase III Study of GSK1278863 in Japanese Non-dialysis (ND) and Peritoneal Dialysis (PD) Subjects With Renal Anemia

Phase 3
Completed
Conditions
Anaemia
Interventions
Drug: 1 to 4 mg tablets of GSK1278863
Drug: Epoetin beta pegol
Drug: 6 mg GSK1278863 tablet
First Posted Date
2016-06-07
Last Posted Date
2021-05-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
355
Registration Number
NCT02791763
Locations
🇯🇵

GSK Investigational Site, Toyama, Japan

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