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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib

Phase 2
Terminated
Conditions
Melanoma
Interventions
First Posted Date
2014-12-11
Last Posted Date
2019-02-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
48
Registration Number
NCT02314143
Locations
🇪🇸

GSK Investigational Site, Madrid, Spain

A 12-Week Efficacy Study of Paracetamol 1000mg Sustained-release Tablets in Patients With Osteoarthritis

Phase 3
Completed
Conditions
Pain
Interventions
First Posted Date
2014-12-09
Last Posted Date
2017-04-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
960
Registration Number
NCT02311881
Locations
🇺🇸

GSK Investigational Site, San Antonio, Texas, United States

A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects

Phase 1
Completed
Conditions
Inflammatory Bowel Diseases
Interventions
Drug: GSK2982772 solution
Drug: GSK2982772 capsule
Drug: Placebo solution
Drug: Placebo capsule
First Posted Date
2014-11-27
Last Posted Date
2017-05-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
79
Registration Number
NCT02302404
Locations
🇬🇧

GSK Investigational Site, Cambridge, United Kingdom

Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Procedure: Spirometry
Other: ACOS clinical questionnaire
First Posted Date
2014-11-27
Last Posted Date
2017-09-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1215
Registration Number
NCT02302417
Locations
🇺🇦

GSK Investigational Site, Kyiv, Ukraine

An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol 100/25 Microgram (mcg) Inhalation Powder, Fluticasone Propionate/Salmeterol 250/50 mcg Inhalation Powder, and Fluticasone Propionate 250 mcg Inhalation Powder in Adults and Adolescents With Persistent Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
First Posted Date
2014-11-26
Last Posted Date
2018-08-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1526
Registration Number
NCT02301975
Locations
🇪🇸

GSK Investigational Site, Valencia, Spain

Safety and Efficacy Study of Losmapimod (GW856553) in Frequently Exacerbating Participants With Chronic Obstructive Pulmonary Disease (COPD)

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
First Posted Date
2014-11-24
Last Posted Date
2018-08-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
184
Registration Number
NCT02299375
Locations
🇪🇸

GSK Investigational Site, Valencia, Spain

A Study to Evaluate the Safety and Ability of the Vaccine to Induce Antibodies Against the Respiratory Syncytial Virus in Healthy Adults

Phase 1
Completed
Conditions
Respiratory Syncytial Virus (RSV)
Interventions
Biological: RSV F subunit 45 μg MF59 adjuvant
Biological: RSV F subunit 90 μg No adjuvant
Biological: RSV F subunit 45 μg Aluminum hydroxide adjuvant
Biological: RSV F subunit 45 μg No adjuvant
Biological: RSV F subunit 135 μg Aluminum hydroxide adjuvant
Drug: Placebo
Biological: RSV F subunit 90 μg Aluminum hydroxide adjuvant
Biological: RSV F subunit 135 μg MF59 adjuvant
Biological: RSV F subunit 90 μg MF59 adjuvant
Biological: RSV F subunit 135 μg No adjuvant
First Posted Date
2014-11-21
Last Posted Date
2018-08-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
288
Registration Number
NCT02298179
Locations
🇧🇪

GSK Investigational Site, Ghent, Belgium

A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae

Phase 2
Completed
Conditions
Gonorrhea
Interventions
Drug: GSK2140944
First Posted Date
2014-11-19
Last Posted Date
2017-05-23
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
106
Registration Number
NCT02294682
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: GSK2269557
Drug: Placebo
First Posted Date
2014-11-19
Last Posted Date
2021-08-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
126
Registration Number
NCT02294734
Locations
🇷🇺

GSK Investigational Site, Yaroslavl, Russian Federation

Single Dose, Pharmacokinetic, Safety, Tolerability and QTc Study of GSK1278863 in Healthy Volunteers

Phase 1
Completed
Conditions
Anaemia
Interventions
Drug: GSK1278863 500 mg
Drug: GSK1278863 75 mg
Drug: Moxifloxacin 400 mg
Drug: Placebo matching GSK1278863
Drug: Placebo matching Moxifloxacin
First Posted Date
2014-11-18
Last Posted Date
2018-07-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
61
Registration Number
NCT02293148
Locations
🇺🇸

GSK Investigational Site, Overland Park, Kansas, United States

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