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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Candidate Vaccine (GSK2321138A) Manufactured Using a New Process in Adults and Children

Phase 3
Completed
Conditions
Influenza
Interventions
Biological: Influsplit Tetra™ vaccine produced by licensed process (LP)
Biological: Influsplit Tetra™ vaccine produced by investigational process (IP)
First Posted Date
2014-08-04
Last Posted Date
2018-06-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
1886
Registration Number
NCT02207413
Locations
🇪🇸

GSK Investigational Site, Sevilla, Spain

An Extension to Study MALARIA-055 PRI (NCT00866619) to Evaluate the Long-term Efficacy, Safety and Immunogenicity of GSK Biologicals' Candidate Malaria Vaccine in Infants and Children in Africa

Phase 3
Completed
Conditions
Malaria
Interventions
Procedure: Blood sampling
Biological: Malaria Vaccine 257049 (MALARIA-055 PRI)
Biological: Meningococcal C Conjugate Vaccine (MALARIA-055 PRI)
Biological: TritanrixHepB/Hib (MALARIA-055 PRI)
Biological: Cell-culture rabies vaccine (MALARIA-055 PRI)
Biological: Polio Sabin Oral Polio Vaccine (GSK) (MALARIA-055 PRI)
First Posted Date
2014-08-04
Last Posted Date
2019-11-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
3084
Registration Number
NCT02207816
Locations
🇹🇿

GSK Investigational Site, Tanga, Tanzania

Evaluation of Pazopanib on Bleeding in Subjects With Hereditary Haemorrhagic Telangiectasia

Phase 2
Terminated
Conditions
Telangiectasia, Hereditary Hemorrhagic
Interventions
Drug: Pazopanib
Drug: Placebo
First Posted Date
2014-07-30
Last Posted Date
2017-07-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
7
Registration Number
NCT02204371
Locations
🇨🇦

GSK Investigational Site, Toronto, Ontario, Canada

A Single Oral Escalating Dose Study of GSK2140944 in Healthy Volunteers

Phase 1
Completed
Conditions
Infections, Respiratory Tract
Interventions
Drug: GSK2140944
Other: Placebo
First Posted Date
2014-07-28
Last Posted Date
2017-06-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
48
Registration Number
NCT02202187
Locations
🇺🇸

GSK Investigational Site, Minneapolis, Minnesota, United States

Pharmacokinetics Study Comparing Topical Diclofenac/Menthol Gels With Voltaren Gel and Oral Diclofenac Sodium

Phase 1
Completed
Conditions
Pain
Interventions
First Posted Date
2014-07-28
Last Posted Date
2017-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
18
Registration Number
NCT02201238
Locations
🇺🇸

GSK Investigational Site, Buffalo, New York, United States

Evaluation of Danirixin (GSK1325756) Inhibition of CD11b Cell Surface Expression

Phase 1
Completed
Conditions
Infections, Respiratory Syncytial Virus
Interventions
Other: CXCL1
Drug: Danirixin
First Posted Date
2014-07-28
Last Posted Date
2017-05-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
40
Registration Number
NCT02201303
Locations
🇺🇸

GSK Investigational Site, Syracuse, New York, United States

A Methodology Study to Evaluate a Sitting Knee Measuring Device in Assessing Growth in Indian Children.

Phase 1
Completed
Conditions
Nutritional Status
Interventions
Dietary Supplement: Nutritional supplement with micronutrient
Dietary Supplement: Nutritional supplement without micronutrient
First Posted Date
2014-07-28
Last Posted Date
2018-01-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
109
Registration Number
NCT02201225
Locations
🇮🇳

GSK Investigational Site, Bangalore, India

A Pilot Study to Determine the Relative Bioavailability of Mosapride 5mg From Two Candidate Formulations of GR107719B Relative to One 5mg Tablet of Reference Mosapride Citrate (GASMOTIN™) in Healthy Adult Human Subjects Under Fasting Conditions

Phase 1
Completed
Conditions
Gastritis
Interventions
Drug: Reference mosapride citrate (GASMOTIN)
Drug: GR107719B (Formulation 1)
Drug: GR107719B (Formulation 2)
First Posted Date
2014-07-28
Last Posted Date
2017-05-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
18
Registration Number
NCT02201316
Locations
🇮🇳

GSK Investigational Site, Hyderabad, India

A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients

Phase 2
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
Drug: GSK2330672
Drug: Placebo
Drug: Sitagliptin
Drug: Metformin
First Posted Date
2014-07-28
Last Posted Date
2017-11-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
70
Registration Number
NCT02202161
Locations
🇺🇸

GSK Investigational Site, San Antonio, Texas, United States

The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ

Not Applicable
Completed
Conditions
Oral Hygiene
Interventions
Drug: Sodium fluoride (250 ppm)
Drug: Sodium fluoride (1150 ppm)
Drug: Sodium fluoride (1426 ppm) + zinc base A
Drug: Sodium fluoride (1426 ppm)
Drug: Fluoride (0 ppm)
Drug: Sodium fluoride (1426 ppm) + zinc base B
First Posted Date
2014-07-21
Last Posted Date
2015-05-01
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
62
Registration Number
NCT02195583
Locations
🇺🇸

GSK Investigational Site, Indianapolis, Indiana, United States

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