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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Clinical Trials

3.8k

Active:153
Completed:3195

Trial Phases

5 Phases

Phase 1:1096
Phase 2:827
Phase 3:937
+2 more phases

Drug Approvals

126

PPB:126

Drug Approvals

OMJJARA TABLETS 100MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 150MG

Approval Date
Dec 13, 2024
PPB

OMJJARA TABLETS 200MG

Approval Date
Dec 13, 2024
PPB

DERMOVATE CREAM 0.05% W/W

Approval Date
Oct 12, 2023
PPB

DERMOVATE OINTMENT 0.05% W/W

Approval Date
Oct 12, 2023
PPB
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Clinical Trials

Distribution across different clinical trial phases (3316 trials with phase data)• Click on a phase to view related trials

Phase 1
1096 (33.1%)
Phase 3
937 (28.3%)
Phase 2
827 (24.9%)
Phase 4
339 (10.2%)
Not Applicable
117 (3.5%)

A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months

Phase 2
Not yet recruiting
Conditions
Malaria
Interventions
Biological: RTS,S/AS01E vaccine
First Posted Date
2025-06-25
Last Posted Date
2025-06-25
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
238
Registration Number
NCT07036159
Locations
🇷🇼

Center for Family Health Research, Kigali, Rwanda

🇷🇼

Rinda Ubuzima Gatenga Medicalized Health Center University of Rwanda, Kigali, Rwanda

A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)

Phase 3
Not yet recruiting
Conditions
Meningitis
Interventions
Biological: rMenB+OMV NZ vaccine
First Posted Date
2025-05-29
Last Posted Date
2025-05-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
312
Registration Number
NCT06995430

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

Phase 1
Recruiting
Conditions
Neoplasms, Prostate
Interventions
Drug: GSK5458514
First Posted Date
2025-05-25
Last Posted Date
2025-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
82
Registration Number
NCT06990880
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GSK3862995B Administered as a Single Dose to Healthy Participants of Chinese, Japanese, and European Ancestry

Phase 1
Not yet recruiting
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: GSK3862995B
Drug: Placebo
First Posted Date
2025-05-20
Last Posted Date
2025-05-20
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
30
Registration Number
NCT06979518

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

Phase 3
Recruiting
Conditions
Asthma
Interventions
First Posted Date
2025-05-18
Last Posted Date
2025-06-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
150
Registration Number
NCT06979323
Locations
🇺🇸

GSK Investigational Site, Plantation, Florida, United States

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News

Nature Study Validates LIXTE's PP2A Inhibitor LB-100 for Enhanced Cancer Immunotherapy

A Nature study led by MD Anderson researchers found that ovarian cancer patients with PPP2R1A mutations had significantly better overall survival when treated with immune checkpoint blockade therapy.

ViiV Healthcare Presents Real-World Data on Long-Acting HIV Treatments at IAS 2025

ViiV Healthcare presented extensive real-world data at IAS 2025 demonstrating the effectiveness, safety, and tolerability of its long-acting injectable HIV treatments, including cabotegravir + rilpivirine LA for treatment and cabotegravir LA for prevention.

Hansa Biopharma Appoints Dr. Richard Philipson as Chief Medical Officer to Lead Next Development Phase

Hansa Biopharma has appointed Dr. Richard Philipson as Chief Medical Officer effective July 14, bringing over 25 years of industry experience to the commercial-stage biopharmaceutical company.

House Republicans Subpoena Former Pfizer Executive Over Alleged COVID-19 Vaccine Trial Delays

House Judiciary Committee subpoenaed former Pfizer executive Dr. Philip Dormitzer over allegations that senior Pfizer executives deliberately slowed COVID-19 vaccine clinical testing before the 2020 election.

bluebird bio Strengthens Leadership Team with Three Key Executive Appointments

bluebird bio, a pioneer in gene therapies for severe genetic diseases, has appointed three new executives to strengthen its leadership team as the company focuses on commercial execution.

Alzheimer's Drug Market Sees 780% Investment Surge Following Leqembi and Kisunla Approvals

Total M&A deal value in Alzheimer's disease jumped from $2 billion in 2022 to $18 billion in 2024, representing a 780% increase following the approval of disease-modifying treatments.

FDA Maintains Record-Breaking Approval Pace Despite Organizational Upheaval, Highlighting Three Breakthrough Therapies

The FDA has approved 84 drugs in 2025 so far, marking the second-highest total for this period despite major organizational changes including 3,500 staff layoffs.

Bharat Biotech and GSK Pledge to Cut Malaria Vaccine Price by More Than Half to Under $5 by 2028

Bharat Biotech and GSK announced they will reduce the price of the world's first malaria vaccine RTS,S by more than half to less than $5 per dose by 2028.

Longeveron Appoints Than Powell as Chief Business Officer to Lead Alzheimer's and HLHS Program Strategy

Longeveron Inc. has appointed Than Powell as Chief Business Officer effective July 7, 2025, to oversee partnering efforts for Alzheimer's disease and international strategy for hypoplastic left heart syndrome programs.

CDC's Reconstituted Vaccine Advisory Panel Votes to Eliminate Thimerosal from All Flu Vaccines

The newly appointed Advisory Committee on Immunization Practices (ACIP) voted 5-1 to recommend thimerosal-free influenza vaccines for all age groups, despite the preservative being present in only 6% of U.S. flu vaccines.

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